Conservation of cofitness between BWI76_RS20390 and BWI76_RS01535 in Klebsiella michiganensis M5al

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 1.0 BWI76_RS01535 thiazole synthase 0.50 14
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.92 GFF4202 Thiazole biosynthesis protein ThiG low > 78
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.90 EX28DRAFT_4532 Uncharacterized enzyme of thiazole biosynthesis low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.90 MPMX20_00213 Thiazole synthase low > 85
Escherichia coli BL21 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.91 ECD_03867 thiamine biosynthesis ThiGH complex subunit low > 61
Escherichia fergusonii Becca 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.91 EFB2_04621 Thiazole synthase low > 86
Escherichia coli Nissle 1917 0.83 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.90 ECOLIN_RS23020 thiazole synthase low > 55
Escherichia coli BW25113 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.91 b3991 thiG thiamin biosynthesis, thiazole moiety (VIMSS) 0.68 11
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.91 OHPLBJKB_04060 Thiazole synthase low > 73
Escherichia coli ECRC62 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 BNILDI_05985 thiG thiazole synthase low > 75
Escherichia coli ECOR27 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 NOLOHH_05540 thiG thiazole synthase low > 75
Escherichia coli ECRC100 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 OKFHMN_13395 thiG thiazole synthase low > 80
Escherichia coli ECRC99 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 KEDOAH_14765 thiG thiazole synthase — —
Escherichia coli ECRC98 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 JDDGAC_17020 thiG thiazole synthase low > 86
Escherichia coli ECRC101 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 MCAODC_03895 thiG thiazole synthase 0.88 15
Escherichia coli ECRC102 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 NIAGMN_11145 thiG thiazole synthase — —
Escherichia coli ECOR38 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.91 HEPCGN_12030 thiG thiazole synthase 0.82 38
Dickeya dadantii 3937 0.75 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB 0.78 DDA3937_RS01155 thiazole synthase low > 74
Dickeya dianthicola ME23 0.74 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB 0.77 DZA65_RS01195 thiazole synthase 0.44 46
Pantoea sp. MT58 0.73 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.36 IAI47_20700 thiazole synthase low > 76
Erwinia tracheiphila SCR3 0.73 LU632_RS07815 DUF3410 domain-containing protein 0.77 LU632_RS00950 thiazole synthase — —
Serratia liquefaciens MT49 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.76 IAI46_01300 thiazole synthase low > 86
Rahnella sp. WP5 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.78 EX31_RS16795 thiazole synthase low > 89
Dickeya dianthicola 67-19 0.70 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB 0.77 HGI48_RS01150 thiazole synthase low > 71
Pectobacterium carotovorum WPP14 0.70 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB 0.79 HER17_RS20400 thiazole synthase low > 75
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_10525 DUF3410 domain-containing protein 0.69 CSW01_00355 thiazole synthase — —
Shewanella sp. ANA-3 0.43 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.65 Shewana3_1940 thiG thiazole synthase (RefSeq) — —
Shewanella oneidensis MR-1 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.65 SO2441 thiG thiG protein (NCBI ptt file) — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.40 Psyr_4740 thiazole-phosphate synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.40 Psyr_4740 thiazole-phosphate synthase — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.40 PfGW456L13_1000 Thiazole biosynthesis protein ThiG — —
Shewanella amazonensis SB2B 0.42 Sama_2153 erythronate-4-phosphate dehydrogenase (RefSeq) 0.68 Sama_1856 thiG thiazole synthase (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_00545 erythronate-4-phosphate dehydrogenase 0.40 AO353_08215 thiazole synthase — —
Shewanella loihica PV-4 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.62 Shew_2092 thiazole biosynthesis family protein (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.39 Pf1N1B4_2331 Thiazole biosynthesis protein ThiG — —
Pseudomonas simiae WCS417 0.41 PS417_07535 erythronate-4-phosphate dehydrogenase 0.40 PS417_26775 thiazole synthase — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_02365 erythronate-4-phosphate dehydrogenase 0.39 AO356_13375 thiazole synthase — —
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.39 Pf6N2E2_4590 Thiazole biosynthesis protein ThiG — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.39 PFLU_RS28420 thiazole synthase — —
Pseudomonas fluorescens SBW25 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.39 PFLU_RS28420 thiazole synthase — —
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_1308 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) 0.43 B158DRAFT_0291 thiazole-phosphate synthase — —
Pseudomonas sp. RS175 0.39 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.39 PFR28_04252 Thiazole synthase — —
Marinobacter adhaerens HP15 0.38 HP15_2098 erythronate-4-phosphate dehydrogenase 0.43 HP15_3274 thiazole synthase — —
Pseudomonas putida KT2440 0.38 PP_2117 Erythronate-4-phosphate dehydrogenase 0.38 PP_5104 thiazole synthase — —
Pseudomonas sp. S08-1 0.37 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.40 OH686_14285 Thiazole synthase — —
Pseudomonas stutzeri RCH2 0.37 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.41 Psest_0267 Uncharacterized enzyme of thiazole biosynthesis — —
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS02440 4-phosphoerythronate dehydrogenase PdxB 0.64 HMPREF1181_RS14680 thiazole synthase — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS10820 4-phosphoerythronate dehydrogenase PdxB 0.63 HMPREF1058_RS03285 thiazole synthase 0.81 33
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS06250 4-phosphoerythronate dehydrogenase PdxB 0.63 ABI39_RS17755 thiazole synthase 0.67 40
Bacteroides ovatus ATCC 8483 0.33 BACOVA_01953 4-phosphoerythronate dehydrogenase 0.65 BACOVA_02359 thiazole biosynthesis protein ThiG low > 94
Bacteroides thetaiotaomicron VPI-5482 0.32 BT3361 erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.65 BT0651 thiamine biosynthesis protein ThiG (NCBI ptt file) low > 81
Alteromonas macleodii MIT1002 0.32 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.66 MIT1002_00093 Thiazole synthase — —
Acinetobacter radioresistens SK82 0.31 MPMX26_02238 Erythronate-4-phosphate dehydrogenase 0.38 MPMX26_01107 Thiazole synthase low > 36

Not shown: 1 genomes with orthologs for BWI76_RS20390 only; 42 genomes with orthologs for BWI76_RS01535 only