Conservation of cofitness between ABZR87_RS08360 and ABZR87_RS11225 in Ralstonia sp. UNC404CL21Col

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS08360 NmrA family NAD(P)-binding protein 1.0 ABZR87_RS11225 DHA2 family efflux MFS transporter permease subunit 0.47 5
Paraburkholderia graminis OAS925 0.87 ABIE53_001892 uncharacterized protein YbjT (DUF2867 family) 0.69 ABIE53_002458 DHA2 family multidrug resistance protein low > 113
Azospirillum sp. SherDot2 0.79 MPMX19_03551 NAD(P)H azoreductase 0.30 MPMX19_05353 Fatty acid resistance protein FarB low > 112
Rhizobium sp. OAE497 0.76 ABIE40_RS30270 NmrA family NAD(P)-binding protein 0.29 ABIE40_RS21925 DHA2 family efflux MFS transporter permease subunit low > 107
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS39260 NmrA/HSCARG family protein 0.69 QEN71_RS23085 DHA2 family efflux MFS transporter permease subunit low > 153
Pseudomonas sp. RS175 0.55 PFR28_02525 hypothetical protein 0.46 PFR28_02747 Multidrug export protein EmrB low > 88
Rahnella sp. WP5 0.55 EX31_RS15565 NmrA/HSCARG family protein 0.55 EX31_RS13660 multidrug efflux MFS transporter permease subunit EmrB low > 89
Pseudomonas fluorescens SBW25 0.54 PFLU_RS16490 NAD(P)H-binding protein 0.45 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS16490 NAD(P)H-binding protein 0.45 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Herbaspirillum seropedicae SmR1 0.53 HSERO_RS02175 NmrA family transcriptional regulator 0.64 HSERO_RS13575 DSBA oxidoreductase low > 78
Burkholderia phytofirmans PsJN 0.53 BPHYT_RS20460 NmrA family transcriptional regulator 0.67 BPHYT_RS08085 DSBA oxidoreductase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.53 H281DRAFT_01250 Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains 0.69 H281DRAFT_05107 MFS transporter, DHA2 family, multidrug resistance protein low > 103
Acidovorax sp. GW101-3H11 0.53 Ac3H11_2242 Oxidoreductase 0.61 Ac3H11_2352 Inner membrane component of tripartite multidrug resistance system low > 79
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_19985 NAD(P)-dependent oxidoreductase 0.34 CA264_07170 MFS transporter low > 74
Sinorhizobium meliloti 1021 0.17 SMa2109 hypothetical protein 0.22 SMc03167 multidrug efflux system protein low > 103
Sphingomonas koreensis DSMZ 15582 0.16 Ga0059261_3756 Predicted nucleoside-diphosphate-sugar epimerases 0.27 Ga0059261_4005 drug resistance transporter, EmrB/QacA subfamily low > 68
Serratia liquefaciens MT49 0.15 IAI46_16795 SDR family oxidoreductase 0.53 IAI46_20005 multidrug efflux MFS transporter permease subunit EmrB low > 86
Agrobacterium fabrum C58 0.15 Atu0949 hypothetical protein 0.25 Atu4479 MFS permease low > 89
Enterobacter sp. TBS_079 0.15 MPMX20_00489 Quinone oxidoreductase 2 0.56 MPMX20_03564 Multidrug export protein EmrB low > 85
Pseudomonas fluorescens FW300-N2E2 0.15 Pf6N2E2_921 putative nucleoside-diphosphate-sugar epimerase 0.45 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system low > 103
Escherichia fergusonii Becca 0.14 EFB2_04317 Quinone oxidoreductase 2 0.54 EFB2_01242 Multidrug export protein EmrB low > 86
Escherichia coli Nissle 1917 0.13 ECOLIN_RS24465 NAD(P)H:quinone oxidoreductase 0.54 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB low > 55
Dickeya dianthicola 67-19 0.13 HGI48_RS10790 SDR family oxidoreductase 0.55 HGI48_RS16835 multidrug efflux MFS transporter permease subunit EmrB low > 71
Enterobacter asburiae PDN3 0.13 EX28DRAFT_3398 Predicted nucleoside-diphosphate-sugar epimerases 0.56 EX28DRAFT_2769 drug resistance transporter, EmrB/QacA subfamily low > 76
Pantoea sp. MT58 0.13 IAI47_03460 SDR family oxidoreductase 0.54 IAI47_04495 multidrug efflux MFS transporter permease subunit EmrB low > 76
Caulobacter crescentus NA1000 Δfur 0.13 CCNA_03480 triphenylmethane reductase (TMR)-like protein 0.21 CCNA_03831 major facilitator superfamily transporter low > 67
Caulobacter crescentus NA1000 0.13 CCNA_03480 triphenylmethane reductase (TMR)-like protein 0.21 CCNA_03831 major facilitator superfamily transporter low > 66
Pectobacterium carotovorum WPP14 0.13 HER17_RS21790 SDR family oxidoreductase 0.55 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB low > 75
Dickeya dadantii 3937 0.13 DDA3937_RS10835 SDR family oxidoreductase 0.54 DDA3937_RS16765 multidrug efflux MFS transporter permease subunit EmrB low > 74
Klebsiella michiganensis M5al 0.12 BWI76_RS02720 NAD(P)-dependent oxidoreductase 0.55 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB low > 92
Escherichia coli BL21 0.12 ECD_04083 NAD(P)H:quinone oxidoreductase 0.54 ECD_02541 multidrug efflux system protein low > 61
Pseudomonas syringae pv. syringae B728a 0.12 Psyr_2311 conserved hypothetical protein 0.44 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.12 Psyr_2311 conserved hypothetical protein 0.44 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Escherichia coli ECRC101 0.12 MCAODC_02570 qorB NAD(P)H:quinone oxidoreductase 0.54 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli ECRC99 0.12 KEDOAH_16100 qorB NAD(P)H:quinone oxidoreductase 0.54 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Escherichia coli ECRC100 0.12 OKFHMN_12055 qorB NAD(P)H:quinone oxidoreductase 0.54 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB low > 80
Escherichia coli ECRC98 0.12 JDDGAC_15695 qorB NAD(P)H:quinone oxidoreductase 0.54 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.12 OHPLBJKB_03822 Quinone oxidoreductase 2 0.54 OHPLBJKB_01047 Multidrug export protein EmrB low > 73
Escherichia coli ECOR27 0.12 NOLOHH_04315 qorB NAD(P)H:quinone oxidoreductase 0.54 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli ECRC102 0.12 NIAGMN_09905 qorB NAD(P)H:quinone oxidoreductase 0.54 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Escherichia coli BW25113 0.12 b4211 ytfG NAD(P)H:quinone oxidoreductase (NCBI) 0.54 b2686 emrB multidrug efflux system protein (NCBI) low > 76
Escherichia coli ECRC62 0.11 BNILDI_07205 qorB NAD(P)H:quinone oxidoreductase 0.54 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Ralstonia solanacearum IBSBF1503 0.11 RALBFv3_RS19655 NAD(P)-dependent oxidoreductase 0.94 RALBFv3_RS15695 MFS transporter low > 76
Ralstonia solanacearum UW163 0.11 UW163_RS19520 NAD(P)-dependent oxidoreductase 0.18 UW163_RS07870 MFS transporter — —
Ralstonia solanacearum GMI1000 0.11 RS_RS21165 NAD(P)-dependent oxidoreductase 0.92 RS_RS06475 MFS transporter low > 80
Escherichia coli ECOR38 0.11 HEPCGN_10250 qorB NAD(P)H:quinone oxidoreductase 0.54 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.10 GFF864 NADPH:quinone oxidoreductase 2 0.55 GFF1593 Multidrug resistance protein B low > 78
Pseudomonas fluorescens GW456-L13 0.10 PfGW456L13_2904 Mlr3941 protein 0.46 PfGW456L13_2606 Inner membrane component of tripartite multidrug resistance system low > 87
Rhodopseudomonas palustris CGA009 0.10 TX73_013995 SDR family oxidoreductase 0.44 TX73_019160 DHA2 family efflux MFS transporter permease subunit low > 86
Ralstonia solanacearum PSI07 0.10 RPSI07_RS03555 NAD(P)-dependent oxidoreductase 0.92 RPSI07_RS17660 MFS transporter low > 81

Not shown: 2 genomes with orthologs for ABZR87_RS08360 only; 32 genomes with orthologs for ABZR87_RS11225 only