Conservation of cofitness between Shewana3_1847 and Shewana3_3760 in Shewanella sp. ANA-3

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Shewanella sp. ANA-3 1.0 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 1.0 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.92 18
Shewanella oneidensis MR-1 0.86 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.99 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.94 8
Shewanella loihica PV-4 0.73 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.88 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.97 1
Shewanella amazonensis SB2B 0.66 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.89 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.93 31
Enterobacter sp. TBS_079 0.57 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.70 MPMX20_00768 3-isopropylmalate dehydrogenase 0.94 4
Alteromonas macleodii MIT1002 0.56 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase 0.66 MIT1002_00948 3-isopropylmalate dehydrogenase 0.97 2
Pantoea sp. MT58 0.56 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.66 IAI47_16005 3-isopropylmalate dehydrogenase 0.97 9
Escherichia coli BW25113 0.56 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.70 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.94 12
Escherichia coli BL21 0.56 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase 0.70 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent low > 60
Escherichia coli ECOR38 0.56 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase low > 85
Klebsiella michiganensis M5al 0.55 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.69 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.88 9
Enterobacter asburiae PDN3 0.55 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.70 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.81 31
Dickeya dianthicola 67-19 0.55 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 HGI48_RS18060 3-isopropylmalate dehydrogenase low > 71
Dickeya dadantii 3937 0.55 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.71 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Dickeya dianthicola ME23 0.55 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.72 45
Escherichia coli ECRC62 0.54 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 BNILDI_08545 leuA 2-isopropylmalate synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE 0.70 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.52 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.70 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Escherichia fergusonii Becca 0.51 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE 0.70 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Escherichia coli Nissle 1917 0.51 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 ECOLIN_RS00395 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC101 0.51 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC98 0.51 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC101 0.51 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC102 0.51 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC99 0.51 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Rahnella sp. WP5 0.51 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.71 EX31_RS03685 3-isopropylmalate dehydrogenase 0.96 3
Escherichia coli ECOR27 0.51 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 NOLOHH_03065 leuA 2-isopropylmalate synthase low > 57
Serratia liquefaciens MT49 0.50 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.71 IAI46_03350 3-isopropylmalate dehydrogenase low > 86
Erwinia tracheiphila SCR3 0.49 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.68 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.75 46
Rhodanobacter denitrificans MT42 0.49 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.42 LRK55_RS09965 3-isopropylmalate dehydrogenase low > 63
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.39 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.90 53
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.41 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase low > 52
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.42 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.79 11
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.47 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.80 8
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS13560 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.38 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.95 25
Bacteroides ovatus ATCC 8483 0.47 BACOVA_00218 phosphoribosyl-ATP diphosphatase 0.40 BACOVA_04600 3-isopropylmalate dehydrogenase 0.94 21
Pectobacterium carotovorum WPP14 0.47 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 HER17_RS03080 3-isopropylmalate dehydrogenase 0.93 35
Lysobacter sp. OAE881 0.47 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.42 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.96 18
Bacteroides thetaiotaomicron VPI-5482 0.47 BT1377 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) 0.39 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.83 37
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS11065 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.39 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.89 29
Phocaeicola dorei CL03T12C01 0.45 ABI39_RS19935 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.39 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.72 22
Phocaeicola vulgatus CL09T03C04 0.45 HMPREF1058_RS06180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.39 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.71 57
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2517 phosphoribosyl-ATP pyrophosphohydrolase 0.40 Echvi_2062 3-isopropylmalate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS03605 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.39 CA265_RS15850 3-isopropylmalate dehydrogenase 0.92 25
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.40 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.42 CA264_09445 3-isopropylmalate dehydrogenase low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.43 A4249_RS09995 3-isopropylmalate dehydrogenase 0.99 9
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_1995 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 0.45 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase — —
Acinetobacter radioresistens SK82 0.27 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE 0.48 MPMX26_00348 3-isopropylmalate dehydrogenase 0.90 20

Not shown: 0 genomes with orthologs for Shewana3_1847 only; 50 genomes with orthologs for Shewana3_3760 only