Conservation of cofitness between Shewana3_1847 and Shewana3_3759 in Shewanella sp. ANA-3

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Shewanella sp. ANA-3 1.0 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 1.0 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.93 12
Shewanella oneidensis MR-1 0.86 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.95 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.94 16
Shewanella loihica PV-4 0.73 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.88 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.96 8
Shewanella amazonensis SB2B 0.66 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.85 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) 0.93 32
Enterobacter sp. TBS_079 0.57 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.72 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 0.94 7
Pantoea sp. MT58 0.56 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 IAI47_16010 3-isopropylmalate dehydratase large subunit 0.97 14
Alteromonas macleodii MIT1002 0.56 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase 0.67 MIT1002_00947 3-isopropylmalate dehydratase large subunit 0.97 5
Escherichia coli BW25113 0.56 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.72 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.94 9
Escherichia coli BL21 0.56 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase 0.72 ECD_00074 3-isopropylmalate dehydratase large subunit low > 60
Escherichia coli ECOR38 0.56 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 85
Klebsiella michiganensis M5al 0.55 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.72 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 0.88 8
Enterobacter asburiae PDN3 0.55 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.72 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit 0.82 28
Dickeya dianthicola 67-19 0.55 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 HGI48_RS18065 3-isopropylmalate dehydratase large subunit low > 71
Dickeya dadantii 3937 0.55 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.71 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit low > 74
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.70 CSW01_12605 3-isopropylmalate dehydratase large subunit low > 62
Dickeya dianthicola ME23 0.55 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.70 51
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE 0.72 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit low > 73
Escherichia coli ECRC62 0.54 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.52 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.71 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 78
Escherichia coli Nissle 1917 0.51 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit — —
Escherichia fergusonii Becca 0.51 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE 0.72 EFB2_03973 3-isopropylmalate dehydratase large subunit low > 86
Escherichia coli ECRC102 0.51 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Escherichia coli ECRC99 0.51 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Escherichia coli ECRC101 0.51 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Escherichia coli ECRC101 0.51 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Escherichia coli ECRC98 0.51 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Escherichia coli ECOR27 0.51 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 57
Rahnella sp. WP5 0.51 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 EX31_RS03690 3-isopropylmalate dehydratase large subunit 0.96 1
Serratia liquefaciens MT49 0.50 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 IAI46_03345 3-isopropylmalate dehydratase large subunit low > 86
Erwinia tracheiphila SCR3 0.49 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.66 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit 0.75 43
Rhodanobacter denitrificans MT42 0.49 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.52 LRK55_RS09975 3-isopropylmalate dehydratase large subunit low > 63
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.51 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit low > 52
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.52 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit 0.93 29
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.52 LRK54_RS10335 3-isopropylmalate dehydratase large subunit 0.80 6
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.60 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.79 10
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS13560 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.49 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit 0.96 8
Bacteroides ovatus ATCC 8483 0.47 BACOVA_00218 phosphoribosyl-ATP diphosphatase 0.51 BACOVA_04603 3-isopropylmalate dehydratase, large subunit 0.95 16
Pectobacterium carotovorum WPP14 0.47 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.70 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.95 13
Bacteroides thetaiotaomicron VPI-5482 0.47 BT1377 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) 0.50 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) 0.84 31
Lysobacter sp. OAE881 0.47 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.53 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit 0.91 48
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS11065 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.50 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit 0.91 22
Phocaeicola vulgatus CL09T03C04 0.45 HMPREF1058_RS06180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.49 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit 0.77 40
Phocaeicola dorei CL03T12C01 0.45 ABI39_RS19935 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.49 ABI39_RS10200 3-isopropylmalate dehydratase large subunit 0.76 11
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2517 phosphoribosyl-ATP pyrophosphohydrolase 0.53 Echvi_2059 3-isopropylmalate dehydratase, large subunit 0.65 50
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS03605 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.56 CA265_RS15830 3-isopropylmalate dehydratase large subunit 0.92 27
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.55 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.54 CA264_09435 3-isopropylmalate dehydratase large subunit low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.52 A4249_RS10005 3-isopropylmalate dehydratase large subunit 0.99 17
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_1995 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 0.51 Synpcc7942_1898 leuC isopropylmalate isomerase large subunit — —
Acinetobacter radioresistens SK82 0.27 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE 0.56 MPMX26_00345 3-isopropylmalate dehydratase large subunit 0.90 21

Not shown: 0 genomes with orthologs for Shewana3_1847 only; 53 genomes with orthologs for Shewana3_3759 only