Conservation of cofitness between Shewana3_1847 and Shewana3_1850 in Shewanella sp. ANA-3

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Shewanella sp. ANA-3 1.0 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 1.0 Shewana3_1850 hisH imidazole glycerol phosphate synthase subunit HisH (RefSeq) 0.92 16
Shewanella oneidensis MR-1 0.86 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.95 SO2070 hisH amidotransferase HisH (NCBI ptt file) 0.94 17
Shewanella loihica PV-4 0.73 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.66 Shew_2201 hisH imidazole glycerol phosphate synthase subunit HisH (RefSeq) 0.96 15
Shewanella amazonensis SB2B 0.66 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.57 Sama_1945 hisH imidazole glycerol phosphate synthase subunit HisH (RefSeq) 0.96 6
Enterobacter sp. TBS_079 0.57 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.46 MPMX20_03005 Imidazole glycerol phosphate synthase subunit HisH 0.92 17
Pantoea sp. MT58 0.56 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.47 IAI47_07075 imidazole glycerol phosphate synthase subunit HisH 0.97 19
Alteromonas macleodii MIT1002 0.56 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase 0.50 MIT1002_02636 Imidazole glycerol phosphate synthase subunit HisH 0.95 19
Escherichia coli BW25113 0.56 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.45 b2023 hisH imidazole glycerol phosphate synthase subunit HisH (NCBI) 0.91 28
Escherichia coli BL21 0.56 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase 0.45 ECD_01925 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit low > 60
Escherichia coli ECOR38 0.56 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 HEPCGN_03205 hisH imidazole glycerol phosphate synthase subunit HisH low > 85
Klebsiella michiganensis M5al 0.55 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.46 BWI76_RS18940 imidazole glycerol phosphate synthase subunit HisH 0.89 5
Enterobacter asburiae PDN3 0.55 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.45 EX28DRAFT_0536 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 0.83 26
Dickeya dianthicola 67-19 0.55 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.48 HGI48_RS09730 imidazole glycerol phosphate synthase subunit HisH low > 71
Dickeya dadantii 3937 0.55 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.49 DDA3937_RS09720 imidazole glycerol phosphate synthase subunit HisH 0.96 6
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.50 CSW01_05765 imidazole glycerol phosphate synthase subunit HisH low > 62
Dickeya dianthicola ME23 0.55 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.48 DZA65_RS10040 imidazole glycerol phosphate synthase subunit HisH — —
Escherichia coli ECRC62 0.54 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 BNILDI_14725 hisH imidazole glycerol phosphate synthase subunit HisH — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE 0.45 OHPLBJKB_01677 Imidazole glycerol phosphate synthase subunit HisH low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.52 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.45 GFF3909 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) low > 78
Escherichia fergusonii Becca 0.51 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE 0.45 EFB2_01833 Imidazole glycerol phosphate synthase subunit HisH low > 86
Escherichia coli Nissle 1917 0.51 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 ECOLIN_RS11960 imidazole glycerol phosphate synthase subunit HisH — —
Escherichia coli ECRC99 0.51 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 KEDOAH_03650 hisH imidazole glycerol phosphate synthase subunit HisH — —
Escherichia coli ECRC101 0.51 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 OKFHMN_24500 hisH imidazole glycerol phosphate synthase subunit HisH — —
Escherichia coli ECRC102 0.51 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.44 NIAGMN_22445 hisH imidazole glycerol phosphate synthase subunit HisH — —
Escherichia coli ECRC98 0.51 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 JDDGAC_28610 hisH imidazole glycerol phosphate synthase subunit HisH — —
Escherichia coli ECRC101 0.51 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 MCAODC_20440 hisH imidazole glycerol phosphate synthase subunit HisH — —
Rahnella sp. WP5 0.51 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.46 EX31_RS11455 imidazole glycerol phosphate synthase subunit HisH 0.93 38
Escherichia coli ECOR27 0.51 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.45 NOLOHH_15815 hisH imidazole glycerol phosphate synthase subunit HisH low > 57
Serratia liquefaciens MT49 0.50 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.47 IAI46_08195 imidazole glycerol phosphate synthase subunit HisH 0.91 5
Erwinia tracheiphila SCR3 0.49 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.47 LU632_RS08930 hisH imidazole glycerol phosphate synthase subunit HisH 0.92 6
Rhodanobacter denitrificans MT42 0.49 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.42 LRK55_RS01370 imidazole glycerol phosphate synthase subunit HisH 0.70 13
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.43 OKGIIK_04965 hisH imidazole glycerol phosphate synthase subunit HisH low > 52
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.44 ABZR86_RS06715 imidazole glycerol phosphate synthase subunit HisH 0.93 20
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.42 LRK54_RS01590 imidazole glycerol phosphate synthase subunit HisH 0.63 46
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.39 Xcc-8004.2945.1 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) 0.79 11
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS13560 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.37 HMPREF1078_RS13575 imidazole glycerol phosphate synthase subunit HisH 0.96 1
Bacteroides ovatus ATCC 8483 0.47 BACOVA_00218 phosphoribosyl-ATP diphosphatase 0.36 BACOVA_00221 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 0.83 61
Pectobacterium carotovorum WPP14 0.47 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.46 HER17_RS12245 imidazole glycerol phosphate synthase subunit HisH 0.91 48
Bacteroides thetaiotaomicron VPI-5482 0.47 BT1377 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) 0.37 BT1380 imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) 0.71 52
Lysobacter sp. OAE881 0.47 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.38 ABIE51_RS13310 imidazole glycerol phosphate synthase subunit HisH low > 62
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS11065 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.35 HMPREF1181_RS11080 imidazole glycerol phosphate synthase subunit HisH 0.81 48
Phocaeicola dorei CL03T12C01 0.45 ABI39_RS19935 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.37 ABI39_RS19920 imidazole glycerol phosphate synthase subunit HisH 0.69 34
Phocaeicola vulgatus CL09T03C04 0.45 HMPREF1058_RS06180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.37 HMPREF1058_RS06165 imidazole glycerol phosphate synthase subunit HisH 0.76 45
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2517 phosphoribosyl-ATP pyrophosphohydrolase 0.37 Echvi_2514 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 0.89 9
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS03605 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.35 CA265_RS03620 imidazole glycerol phosphate synthase subunit HisH 0.95 5
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.34 ABZR88_RS06865 imidazole glycerol phosphate synthase subunit HisH — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.35 CA264_05100 imidazole glycerol phosphate synthase subunit HisH low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.37 A4249_RS10705 imidazole glycerol phosphate synthase subunit HisH 0.99 32
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_1995 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 0.30 Synpcc7942_1481 hisH imidazole glycerol phosphate synthase subunit HisH — —
Acinetobacter radioresistens SK82 0.27 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE 0.32 MPMX26_02846 Imidazole glycerol phosphate synthase subunit HisH 0.98 8

Not shown: 0 genomes with orthologs for Shewana3_1847 only; 53 genomes with orthologs for Shewana3_1850 only