Conservation of cofitness between b2026 and b3771 in Escherichia coli BW25113

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 1.0 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.95 3
Escherichia coli BL21 1.00 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase 1.00 ECD_03649 dihydroxyacid dehydratase low > 60
Escherichia coli ECRC101 0.99 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECOR38 0.99 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Escherichia coli ECRC101 0.99 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC98 0.99 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.99 ECOLIN_RS21665 dihydroxy-acid dehydratase — —
Escherichia coli ECRC102 0.99 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 0.99 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC62 0.98 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Escherichia fergusonii Becca 0.98 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE 0.99 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.96 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE 1.00 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia coli ECOR27 0.92 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 1.00 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Enterobacter sp. TBS_079 0.91 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.97 MPMX20_04499 Dihydroxy-acid dehydratase 0.93 12
Enterobacter asburiae PDN3 0.91 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.96 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.79 33
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.97 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Klebsiella michiganensis M5al 0.87 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.96 BWI76_RS00975 dihydroxy-acid dehydratase 0.89 4
Dickeya dadantii 3937 0.81 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.92 DDA3937_RS20155 dihydroxy-acid dehydratase 0.89 21
Pantoea sp. MT58 0.81 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.89 IAI47_01035 dihydroxy-acid dehydratase 0.97 8
Dickeya dianthicola 67-19 0.80 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.91 HGI48_RS20295 dihydroxy-acid dehydratase low > 71
Dickeya dianthicola ME23 0.80 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.91 DZA65_RS21335 dihydroxy-acid dehydratase 0.77 36
Erwinia tracheiphila SCR3 0.76 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.86 LU632_RS24400 ilvD dihydroxy-acid dehydratase low > 74
Serratia liquefaciens MT49 0.76 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.90 IAI46_24345 dihydroxy-acid dehydratase low > 86
Rahnella sp. WP5 0.76 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.87 EX31_RS15005 dihydroxy-acid dehydratase 0.95 12
Pectobacterium carotovorum WPP14 0.70 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.91 HER17_RS01075 dihydroxy-acid dehydratase 0.95 17
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.85 CSW01_00140 dihydroxy-acid dehydratase low > 62
Alteromonas macleodii MIT1002 0.63 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase 0.79 MIT1002_04041 Dihydroxy-acid dehydratase 0.94 29
Shewanella oneidensis MR-1 0.62 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.80 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.95 7
Shewanella amazonensis SB2B 0.61 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.79 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.96 8
Shewanella sp. ANA-3 0.60 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.80 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.94 5
Shewanella loihica PV-4 0.57 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.78 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.95 23
Rhodanobacter denitrificans MT42 0.56 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.26 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Rhodanobacter sp. FW510-T8 0.55 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.27 OKGIIK_13600 ilvD dihydroxy-acid dehydratase low > 52
Rhodanobacter denitrificans FW104-10B01 0.55 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.74 22
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.28 ABZR86_RS15945 dihydroxy-acid dehydratase 0.91 45
Mucilaginibacter yixingensis YX-36 DSM 26809 0.54 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase — —
Xanthomonas campestris pv. campestris strain 8004 0.54 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.72 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.52 CA265_RS03605 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.92 23
Echinicola vietnamensis KMM 6221, DSM 17526 0.52 Echvi_2517 phosphoribosyl-ATP pyrophosphohydrolase 0.29 Echvi_2055 dihydroxy-acid dehydratase 0.88 12
Bacteroides ovatus ATCC 8483 0.51 BACOVA_00218 phosphoribosyl-ATP diphosphatase 0.62 BACOVA_03302 dihydroxy-acid dehydratase 0.94 22
Bacteroides thetaiotaomicron VPI-5482 0.51 BT1377 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) 0.63 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.92 12
Bacteroides stercoris CC31F 0.50 HMPREF1181_RS11065 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.64 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.85 36
Parabacteroides merdae CL09T00C40 0.50 HMPREF1078_RS13560 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.65 HMPREF1078_RS16695 dihydroxy-acid dehydratase low > 61
Phocaeicola dorei CL03T12C01 0.49 ABI39_RS19935 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.64 ABI39_RS12715 dihydroxy-acid dehydratase 0.77 10
Phocaeicola vulgatus CL09T03C04 0.49 HMPREF1058_RS06180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.64 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.92 18
Pontibacter actiniarum KMM 6156, DSM 19842 0.48 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.28 CA264_06935 dihydroxy-acid dehydratase low > 74
Lysobacter sp. OAE881 0.47 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.95 29
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.25 A4249_RS10030 dihydroxy-acid dehydratase 0.99 14
Synechococcus elongatus PCC 7942 0.35 Synpcc7942_1995 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 0.75 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Acinetobacter radioresistens SK82 0.31 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE 0.29 MPMX26_03019 Dihydroxy-acid dehydratase low > 36

Not shown: 0 genomes with orthologs for b2026 only; 52 genomes with orthologs for b3771 only