Conservation of cofitness between b0487 and b4478 in Escherichia coli BW25113

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0487 cueR DNA-binding transcriptional activator of copper-responsive regulon genes (NCBI) 1.0 b4478 dgoD galactonate dehydratase (NCBI) 0.15 20
Escherichia coli ECRC62 1.00 BNILDI_22420 cueR Cu(I)-responsive transcriptional regulator 1.00 BNILDI_04320 dgoD galactonate dehydratase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03187 HTH-type transcriptional regulator CueR 1.00 OHPLBJKB_00011 D-galactonate dehydratase low > 73
Escherichia coli ECOR27 1.00 NOLOHH_01000 cueR Cu(I)-responsive transcriptional regulator 1.00 NOLOHH_07210 dgoD galactonate dehydratase low > 57
Escherichia coli BL21 1.00 ECD_00438 copper-responsive regulon transcriptional regulator 1.00 ECD_03575 D-galactonate dehydratase low > 60
Escherichia coli Nissle 1917 0.99 ECOLIN_RS02880 Cu(I)-responsive transcriptional regulator 1.00 ECOLIN_RS21265 galactonate dehydratase — —
Escherichia fergusonii Becca 0.98 EFB2_03572 HTH-type transcriptional regulator CueR 0.99 EFB2_00011 D-galactonate dehydratase low > 86
Escherichia coli ECOR38 0.96 HEPCGN_06670 cueR Cu(I)-responsive transcriptional regulator 1.00 HEPCGN_13775 dgoD galactonate dehydratase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF4405 HTH-type transcriptional regulator cueR 0.94 GFF1765 Galactonate dehydratase (EC 4.2.1.6) low > 78
Enterobacter sp. TBS_079 0.88 MPMX20_01085 HTH-type transcriptional regulator CueR 0.95 MPMX20_00011 D-galactonate dehydratase low > 85
Enterobacter asburiae PDN3 0.86 EX28DRAFT_2473 Cu(I)-responsive transcriptional regulator 0.95 EX28DRAFT_3979 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily low > 76
Klebsiella michiganensis M5al 0.86 BWI76_RS06910 transcriptional regulator 0.94 BWI76_RS27935 galactonate dehydratase low > 92
Rahnella sp. WP5 0.77 EX31_RS22580 Cu(I)-responsive transcriptional regulator 0.87 EX31_RS10320 galactonate dehydratase low > 89
Pantoea sp. MT58 0.75 IAI47_14395 Cu(I)-responsive transcriptional regulator 0.88 IAI47_00045 galactonate dehydratase low > 76
Dickeya dianthicola 67-19 0.73 HGI48_RS05895 Cu(I)-responsive transcriptional regulator 0.85 HGI48_RS06940 galactonate dehydratase low > 71
Dickeya dianthicola ME23 0.73 DZA65_RS06230 Cu(I)-responsive transcriptional regulator 0.85 DZA65_RS07285 galactonate dehydratase low > 75
Pectobacterium carotovorum WPP14 0.70 HER17_RS15620 Cu(I)-responsive transcriptional regulator 0.27 HER17_RS07505 mandelate racemase/muconate lactonizing enzyme family protein low > 75
Ralstonia sp. UNC404CL21Col 0.46 ABZR87_RS04230 Cu(I)-responsive transcriptional regulator 0.84 ABZR87_RS01445 galactonate dehydratase low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.45 Psyr_0653 transcriptional regulator, MerR family 0.62 Psyr_1989 galactonate dehydratase low > 86
Pseudomonas syringae pv. syringae B728a 0.45 Psyr_0653 transcriptional regulator, MerR family 0.62 Psyr_1989 galactonate dehydratase low > 86
Ralstonia solanacearum PSI07 0.45 RPSI07_RS08315 Cu(I)-responsive transcriptional regulator 0.82 RPSI07_RS11425 galactonate dehydratase low > 81
Ralstonia solanacearum UW163 0.45 UW163_RS04655 Cu(I)-responsive transcriptional regulator 0.09 UW163_RS14100 muconate cycloisomerase — —
Ralstonia solanacearum GMI1000 0.45 RS_RS16770 Cu(I)-responsive transcriptional regulator 0.82 RS_RS13765 D-galactonate dehydratase low > 80
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS08955 Cu(I)-responsive transcriptional regulator 0.09 RALBFv3_RS00765 muconate cycloisomerase low > 76
Paraburkholderia sabiae LMG 24235 0.45 QEN71_RS23915 Cu(I)-responsive transcriptional regulator 0.64 QEN71_RS02295 galactonate dehydratase low > 153
Sinorhizobium meliloti 1021 0.44 SM_b21579 MerR family transcriptional regulator 0.66 SM_b20510 galactonate dehydratase low > 103
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS06865 MerR family transcriptional regulator 0.65 BPHYT_RS16405 galactonate dehydratase [EC: 4.2.1.6] (from data) low > 109
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_04982 transcriptional regulator, MerR family 0.65 H281DRAFT_04215 galactonate dehydratase low > 103
Azospirillum brasilense Sp245 0.43 AZOBR_RS19845 MerR family transcriptional regulator 0.22 AZOBR_RS04900 dehydratase low > 97
Azospirillum sp. SherDot2 0.42 MPMX19_04396 HTH-type transcriptional regulator HmrR 0.26 MPMX19_03902 D-galactonate dehydratase low > 112
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_25 Cu(I)-responsive transcriptional regulator 0.62 PfGW456L13_2128 Galactonate dehydratase (EC 4.2.1.6) low > 87
Pseudomonas sp. RS175 0.42 PFR28_05243 HTH-type transcriptional regulator HmrR 0.62 PFR28_02985 D-galactonate dehydratase low > 88
Bosea sp. OAE506 0.41 ABIE41_RS15580 Cu(I)-responsive transcriptional regulator 0.20 ABIE41_RS08260 mandelate racemase/muconate lactonizing enzyme family protein low > 77
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_3488 Cu(I)-responsive transcriptional regulator 0.62 Pf6N2E2_5977 Galactonate dehydratase (EC 4.2.1.6) low > 103
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_08070 transcriptional regulator 0.62 AO356_20290 galactonate dehydratase low > 104
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_1263 Cu(I)-responsive transcriptional regulator 0.62 Pf1N1B4_398 Galactonate dehydratase (EC 4.2.1.6) low > 87
Pseudomonas simiae WCS417 0.41 PS417_03155 transcriptional regulator 0.62 PS417_00165 galactonate dehydratase low > 88
Herbaspirillum seropedicae SmR1 0.41 HSERO_RS08015 MerR family transcriptional regulator 0.60 HSERO_RS05150 galactonate dehydratase low > 78
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS03235 Cu(I)-responsive transcriptional regulator 0.62 PFLU_RS00160 galactonate dehydratase low > 109
Pseudomonas fluorescens SBW25 0.40 PFLU_RS03235 Cu(I)-responsive transcriptional regulator 0.62 PFLU_RS00160 galactonate dehydratase low > 109
Phaeobacter inhibens DSM 17395 0.40 PGA1_c02530 HTH-type transcriptional regulator 0.19 PGA1_c04540 putative d-galactonate dehydratase low > 62
Acinetobacter radioresistens SK82 0.40 MPMX26_01947 HTH-type transcriptional regulator HmrR 0.09 MPMX26_01691 Muconate cycloisomerase 1 — —
Rhizobium sp. OAE497 0.37 ABIE40_RS20305 Cu(I)-responsive transcriptional regulator 0.67 ABIE40_RS17095 galactonate dehydratase low > 107
Agrobacterium fabrum C58 0.37 Atu0938 transcriptional regulator, MerR family 0.23 Atu4196 hypothetical protein low > 89
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS01745 heavy metal-responsive transcriptional regulator 0.62 ABZR86_RS01215 galactonate dehydratase low > 74
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_05540 heavy metal-responsive transcriptional regulator 0.61 OKGIIK_12510 dgoD galactonate dehydratase low > 52

Not shown: 27 genomes with orthologs for b0487 only; 8 genomes with orthologs for b4478 only