Conservation of cofitness between b2307 and b3828 in Escherichia coli BW25113

48 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2307 hisM histidine/lysine/arginine/ornithine transporter subunit (NCBI) 1.0 b3828 metR DNA-binding transcriptional activator, homocysteine-binding (NCBI) 0.19 7
Escherichia coli Nissle 1917 1.00 ECOLIN_RS13380 ABC transporter permease 1.00 ECOLIN_RS30005 HTH-type transcriptional regulator MetR
Escherichia coli BL21 1.00 ECD_02232 histidine ABC transporter permease 1.00 ECD_03707 methionine biosynthesis regulon transcriptional regulator low > 60
Escherichia fergusonii Becca 1.00 EFB2_01551 Histidine transport system permease protein HisM 1.00 EFB2_04809 HTH-type transcriptional regulator MetR low > 86
Escherichia coli ECRC99 0.99 KEDOAH_05455 hisM Histidine transport system permease protein HisM 1.00 KEDOAH_13820 metR HTH-type transcriptional regulator MetR
Escherichia coli ECRC98 0.99 JDDGAC_26700 hisM Histidine transport system permease protein HisM 1.00 JDDGAC_17955 metR HTH-type transcriptional regulator MetR
Escherichia coli ECOR27 0.99 NOLOHH_14360 hisM Histidine transport system permease protein HisM 1.00 NOLOHH_06460 metR HTH-type transcriptional regulator MetR low > 57
Escherichia coli ECOR38 0.99 HEPCGN_21935 hisM Histidine transport system permease protein HisM 1.00 HEPCGN_13030 metR HTH-type transcriptional regulator MetR low > 85
Escherichia coli ECRC62 0.99 BNILDI_13280 hisM Histidine transport system permease protein HisM 1.00 BNILDI_05070 metR HTH-type transcriptional regulator MetR
Escherichia coli ECRC101 0.99 MCAODC_13780 hisM Histidine transport system permease protein HisM 1.00 MCAODC_04835 metR HTH-type transcriptional regulator MetR
Escherichia coli ECRC102 0.99 NIAGMN_20510 hisM Histidine transport system permease protein HisM 1.00 NIAGMN_12085 metR HTH-type transcriptional regulator MetR
Escherichia coli ECRC101 0.99 OKFHMN_22740 hisM Histidine transport system permease protein HisM 1.00 OKFHMN_14330 metR HTH-type transcriptional regulator MetR
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01398 Histidine transport system permease protein HisM 1.00 OHPLBJKB_04223 HTH-type transcriptional regulator MetR low > 73
Klebsiella michiganensis M5al 0.95 BWI76_RS20325 histidine/lysine/arginine/ornithine ABC transporter permease HisM 0.88 BWI76_RS01275 LysR family transcriptional regulator low > 92
Enterobacter asburiae PDN3 0.95 EX28DRAFT_0297 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 0.94 EX28DRAFT_4493 Transcriptional regulator low > 76
Enterobacter sp. TBS_079 0.94 MPMX20_03242 Histidine transport system permease protein HisM 0.94 MPMX20_04452 HTH-type transcriptional regulator MetR low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF1916 Histidine ABC transporter, permease protein HisM (TC 3.A.1.3.1) 0.92 GFF253 Transcriptional activator MetR low > 78
Pantoea sp. MT58 0.91 IAI47_06295 ABC transporter permease 0.80 IAI47_18315 HTH-type transcriptional regulator MetR low > 76
Serratia liquefaciens MT49 0.85 IAI46_17790 ABC transporter permease 0.83 IAI46_01030 HTH-type transcriptional regulator MetR low > 86
Rahnella sp. WP5 0.84 EX31_RS19550 ABC transporter permease 0.88 EX31_RS25370 HTH-type transcriptional regulator MetR low > 89
Pectobacterium carotovorum WPP14 0.82 HER17_RS07040 ABC transporter permease 0.84 HER17_RS20690 HTH-type transcriptional regulator MetR low > 75
Dickeya dadantii 3937 0.81 DDA3937_RS14415 ABC transporter permease 0.87 DDA3937_RS20385 HTH-type transcriptional regulator MetR low > 74
Dickeya dianthicola 67-19 0.80 HGI48_RS14385 ABC transporter permease 0.87 HGI48_RS00815 HTH-type transcriptional regulator MetR low > 71
Dickeya dianthicola ME23 0.80 DZA65_RS15315 ABC transporter permease 0.87 DZA65_RS00870 HTH-type transcriptional regulator MetR low > 75
Paraburkholderia sabiae LMG 24235 0.70 QEN71_RS24875 ABC transporter permease 0.31 QEN71_RS19730 LysR family transcriptional regulator low > 153
Burkholderia phytofirmans PsJN 0.70 BPHYT_RS05500 histidine/lysine/arginine/ornithine ABC transporter permease HisM 0.36 BPHYT_RS26650 LysR family transcriptional regulator
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS29655 amino acid ABC transporter permease 0.34 RR42_RS30655 LysR family transcriptional regulator low > 128
Pseudomonas syringae pv. syringae B728a 0.64 Psyr_3876 amino acid ABC transporter membrane protein 2, PAAT family 0.43 Psyr_3917 transcriptional regulator, LysR family low > 86
Pseudomonas fluorescens FW300-N1B4 0.64 Pf1N1B4_3177 Histidine ABC transporter, permease protein HisM (TC 3.A.1.3.1) 0.42 Pf1N1B4_784 Transcriptional activator MetR low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.64 Psyr_3876 amino acid ABC transporter membrane protein 2, PAAT family 0.43 Psyr_3917 transcriptional regulator, LysR family low > 86
Pseudomonas fluorescens FW300-N2E3 0.64 AO353_25650 amino acid ABC transporter permease 0.42 AO353_16210 XRE family transcriptional regulator low > 101
Pseudomonas simiae WCS417 0.63 PS417_06405 amino acid ABC transporter permease 0.42 PS417_05455 XRE family transcriptional regulator low > 88
Pseudomonas fluorescens SBW25 0.62 PFLU_RS06470 ABC transporter permease 0.42 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.62 PFLU_RS06470 ABC transporter permease 0.42 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_385 Histidine ABC transporter, permease protein HisM (TC 3.A.1.3.1) 0.42 PfGW456L13_4778 Transcriptional activator MetR low > 87
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_05505 ABC transporter for L-Lysine, permease component 2 (from data) 0.43 AO356_17735 XRE family transcriptional regulator low > 104
Pseudomonas sp. RS175 0.62 PFR28_00505 Histidine transport system permease protein HisM 0.43 PFR28_03478 HTH-type transcriptional regulator MetR low > 88
Pseudomonas fluorescens FW300-N2E2 0.61 Pf6N2E2_2960 ABC transporter for L-Lysine, permease component 2 (from data) 0.42 Pf6N2E2_5471 Transcriptional activator MetR low > 103
Castellaniella sp019104865 MT123 0.61 ABCV34_RS02175 histidine ABC transporter permease HisM 0.38 ABCV34_RS04450 LysR substrate-binding domain-containing protein low > 48
Pseudomonas sp. S08-1 0.42 OH686_21265 Arginine/ornithine ABC transporter, permease protein AotM 0.43 OH686_20465 Transcriptional activator MetR low > 80
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_09320 amino acid ABC transporter permease 0.55 CSW01_08580 HTH-type transcriptional regulator MetR low > 62
Marinobacter adhaerens HP15 0.38 HP15_3033 amino acid ABC transporter, inner membrane subunit 0.33 HP15_458 transcriptional regulator, LysR family protein low > 73
Pseudomonas putida KT2440 0.38 PP_4484 histidine / lysine / arginine / ornithine ABC transporter - permease subunit 0.42 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding low > 96
Azospirillum sp. SherDot2 0.33 MPMX19_03639 Octopine transport system permease protein OccM 0.29 MPMX19_00645 HTH-type transcriptional regulator MetR low > 112
Azospirillum brasilense Sp245 0.33 AZOBR_RS00675 ABC transporter permease 0.29 AZOBR_RS24270 LysR family transcriptional regulator low > 97
Pseudomonas stutzeri RCH2 0.32 Psest_0136 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 0.43 Psest_1450 Transcriptional regulator
Agrobacterium fabrum C58 0.31 Atu6025 ABC transporter, membrane spanning protein (nopaline) 0.29 Atu3827 LysR family transcriptional regulator low > 89
Dinoroseobacter shibae DFL-12 0.25 Dshi_2224 polar amino acid ABC transporter, inner membrane subunit (RefSeq) 0.37 Dshi_2079 transcriptional regulator, LysR family (RefSeq) low > 64
Phaeobacter inhibens DSM 17395 0.24 PGA1_c11550 putative histidine transport system permease protein 0.37 PGA1_c11710 transcriptional regulator, LysR family low > 62

Not shown: 5 genomes with orthologs for b2307 only; 18 genomes with orthologs for b3828 only