| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Sphingobium sp. HT1-2 | GFF3809 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | cofit | 100 | 100 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_4162 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 54 | 93 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_00625 | | serine hydrolase | insig. | 32 | 69 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0678 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 30 | 71 |
| | Lysobacter sp. OAE881 | ABIE51_RS13660 | | serine hydrolase domain-containing protein | insig. | 31 | 67 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09335 | | serine hydrolase | insig. | 28 | 70 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_12395 | | Serine hydrolase | insig. | 29 | 71 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1849.1 | | Beta-lactamase (EC 3.5.2.6) | insig. | 30 | 76 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS17060 | | beta-lactamase family protein | insig. | 29 | 68 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS11465 | | serine hydrolase | insig. | 29 | 67 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS23910 | | serine hydrolase | insig. | 26 | 75 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS11195 | | serine hydrolase domain-containing protein | insig. | 29 | 67 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4014 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 28 | 67 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12150 | | serine hydrolase domain-containing protein | insig. | 29 | 64 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1175 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 30 | 70 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08185 | | hypothetical protein | insig. | 27 | 75 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1344 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 29 | 74 |
| | Variovorax sp. SCN45 | GFF459 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily / DUF3471 domain | insig. | 26 | 67 |
| | Lysobacter sp. OAE881 | ABIE51_RS11230 | | serine hydrolase | insig. | 27 | 75 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS01200 | | serine hydrolase | insig. | 30 | 66 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS02905 | | serine hydrolase | insig. | 27 | 55 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS01435 | | serine hydrolase | insig. | 30 | 66 |
| | Variovorax sp. OAS795 | ABID97_RS13020 | | serine hydrolase | insig. | 28 | 70 |
| | Sphingobium sp. HT1-2 | GFF2759 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 32 | 48 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS00270 | | serine hydrolase | cofit | 29 | 68 |
| | Variovorax sp. SCN45 | GFF2397 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 29 | 64 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_06670 | | hypothetical protein | insig. | 27 | 70 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS23115 | | serine hydrolase | insig. | 27 | 64 |
| | Rhodopseudomonas palustris CGA009 | TX73_008260 | | serine hydrolase | insig. | 29 | 49 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_05105 | ampC | serine hydrolase | insig. | 30 | 76 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS14480 | | serine hydrolase domain-containing protein | insig. | 29 | 53 |
| | Mycobacterium tuberculosis H37Rv | Rv1730c | | Possible penicillin-binding protein | insig. | 28 | 64 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2342 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 28 | 49 |
| | Caulobacter crescentus NA1000 | CCNA_02190 | | penicillin-binding protein | sig. | 27 | 64 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02190 | | penicillin-binding protein | cofit | 27 | 64 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1656 | | D-alanyl-D-alanine dipeptidase | insig. | 29 | 64 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS08605 | | serine hydrolase | insig. | 30 | 67 |
| | Lysobacter sp. OAE881 | ABIE51_RS15060 | | serine hydrolase | insig. | 29 | 73 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06895 | | serine hydrolase | insig. | 25 | 62 |
| | Pseudomonas simiae WCS417 | PS417_14945 | | beta-lactamase | strong | 28 | 64 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12140 | | serine hydrolase domain-containing protein | insig. | 29 | 67 |
| | Shewanella amazonensis SB2B | Sama_1351 | | beta-lactamase class C-like protein (RefSeq) | insig. | 27 | 65 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS11025 | | serine hydrolase | insig. | 29 | 64 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1439 | | Beta-lactamase | insig. | 27 | 58 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1439 | | Beta-lactamase | insig. | 27 | 58 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0658 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 30 | 54 |
| | Caulobacter crescentus NA1000 | CCNA_03294 | | beta-lactamase family protein | cofit | 28 | 43 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03294 | | beta-lactamase family protein | cofit | 28 | 43 |
| | Marinobacter adhaerens HP15 | HP15_986 | | beta-lactamase | cofit | 26 | 44 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3004 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 27 | 73 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0836 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 30 | 52 |
| | Escherichia coli ECOR27 | NOLOHH_13805 | pbp4b | penicillin binding protein PBP4B | insig. | 33 | 38 |
| | Escherichia coli ECRC62 | BNILDI_12670 | pbp4b | penicillin binding protein PBP4B | cofit | 33 | 38 |
| | Lysobacter sp. OAE881 | ABIE51_RS13670 | | serine hydrolase | insig. | 27 | 74 |
| | Rhodopseudomonas palustris CGA009 | TX73_002380 | | serine hydrolase | strong | 32 | 48 |
| | Escherichia coli ECRC100 | OKFHMN_22125 | pbp4b | penicillin binding protein PBP4B | cofit | 31 | 46 |
| | Escherichia coli ECRC101 | MCAODC_12655 | pbp4b | penicillin binding protein PBP4B | insig. | 31 | 46 |
| | Escherichia coli ECRC102 | NIAGMN_19895 | pbp4b | penicillin binding protein PBP4B | insig. | 31 | 46 |
| | Escherichia coli ECRC98 | JDDGAC_26075 | pbp4b | penicillin binding protein PBP4B | insig. | 31 | 46 |
| | Escherichia coli ECRC99 | KEDOAH_06095 | pbp4b | penicillin binding protein PBP4B | no data | 31 | 46 |
| | Pseudomonas sp. SVBP6 | COO64_RS00130 | | serine hydrolase | insig. | 29 | 55 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS19890 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 28 | 67 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1573.1 | | Beta-lactamase (EC 3.5.2.6) | strong | 26 | 71 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01293 | | hypothetical protein | insig. | 32 | 38 |
| | Escherichia coli ECOR38 | HEPCGN_21300 | pbp4b | penicillin binding protein PBP4B | insig. | 33 | 38 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1705 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 29 | 60 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1650 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 27 | 65 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS10325 | | serine hydrolase | insig. | 26 | 90 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS25255 | | 1,4-butanediol diacrylate esterase | insig. | 29 | 45 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2755 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 26 | 73 |
| | Escherichia coli BW25113 | b2430 | b2430 | putative beta-lactamase (VIMSS) | insig. | 33 | 38 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20415 | | serine hydrolase | insig. | 26 | 64 |
| | Mycobacterium tuberculosis H37Rv | Rv1922 | | Probable conserved lipoprotein | insig. | 27 | 46 |
| | Pantoea sp. MT58 | IAI47_05345 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 27 | 67 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12850 | | serine hydrolase domain-containing protein | insig. | 26 | 68 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1807 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 27 | 66 |
| | Caulobacter crescentus NA1000 | CCNA_01570 | | penicillin-binding protein | insig. | 27 | 64 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01570 | | penicillin-binding protein | cofit | 27 | 64 |
| | Escherichia coli ECOR38 | HEPCGN_07305 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1698 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 34 | 35 |
| | Escherichia coli ECOR27 | NOLOHH_01590 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Escherichia coli ECRC100 | OKFHMN_08665 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Escherichia coli ECRC101 | MCAODC_27890 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Escherichia coli ECRC102 | NIAGMN_06720 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | cofit | 25 | 71 |
| | Escherichia coli ECRC62 | BNILDI_23000 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Escherichia coli ECRC98 | JDDGAC_12320 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Escherichia coli ECRC99 | KEDOAH_19305 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | no data | 25 | 71 |
| | Caulobacter crescentus NA1000 | CCNA_01639 | | beta-lactamase family protein | insig. | 28 | 46 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01639 | | beta-lactamase family protein | insig. | 28 | 46 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4271 | | Penicillin-binding protein AmpH | insig. | 26 | 71 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03299 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Escherichia coli BW25113 | b0376 | ampH | beta-lactamase/D-alanine carboxypeptidase (NCBI) | sig. | 25 | 71 |
| | Escherichia fergusonii Becca | EFB2_03681 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS02290 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 25 | 71 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS10980 | | beta-lactamase | insig. | 29 | 44 |
| | Shewanella sp. ANA-3 | Shewana3_1990 | ampC | beta-lactamase (RefSeq) | insig. | 29 | 52 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08675 | | hypothetical protein | sig. | 27 | 47 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_13340 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | cofit | 25 | 67 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_18155 | | serine hydrolase | insig. | 26 | 68 |
| | Erwinia tracheiphila SCR3 | LU632_RS21660 | ampH | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 25 | 67 |