Conservation of cofitness between Rv3433c and Rv3010c in Mycobacterium tuberculosis H37Rv

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Mycobacterium tuberculosis H37Rv 1.0 Rv3433c Conserved protein 1.0 Rv3010c Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.38 15
Rhodanobacter denitrificans FW104-10B01 0.18 LRK54_RS15135 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.11 LRK54_RS06620 6-phosphofructokinase low > 59
Rhodanobacter denitrificans MT42 0.18 LRK55_RS14850 NAD(P)H-hydrate dehydratase 0.11 LRK55_RS06365 6-phosphofructokinase low > 63
Alteromonas macleodii MIT1002 0.18 MIT1002_03793 Nicotinamide nucleotide repair protein 0.27 MIT1002_01991 6-phosphofructokinase isozyme 1 low > 70
Bacteroides stercoris CC31F 0.17 HMPREF1181_RS06260 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.39 HMPREF1181_RS02415 6-phosphofructokinase low > 56
Parabacteroides merdae CL09T00C40 0.17 HMPREF1078_RS15325 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.39 HMPREF1078_RS07070 ATP-dependent 6-phosphofructokinase low > 61
Bacteroides ovatus ATCC 8483 0.17 BACOVA_05215 YjeF domain protein 0.39 BACOVA_01958 phosphofructokinase low > 94
Rahnella sp. WP5 0.17 EX31_RS08845 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.28 EX31_RS14310 6-phosphofructokinase low > 89
Phocaeicola vulgatus CL09T03C04 0.16 HMPREF1058_RS00705 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.41 HMPREF1058_RS10725 6-phosphofructokinase low > 67
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS08310 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.40 ABI39_RS06375 6-phosphofructokinase low > 72
Rhodanobacter sp. FW510-T8 0.16 OKGIIK_03905 Bifunctional NAD(P)H-hydrate repair enzyme 0.11 OKGIIK_17005 pfkA 6-phosphofructokinase low > 52
Bacteroides thetaiotaomicron VPI-5482 0.16 BT4383 putative sugar kinase (NCBI ptt file) 0.40 BT3356 6-phosphofructokinase (NCBI ptt file) 0.22 22
Pedobacter sp. GW460-11-11-14-LB5 0.16 CA265_RS24885 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.30 CA265_RS02195 6-phosphofructokinase — —
Pectobacterium carotovorum WPP14 0.16 HER17_RS02560 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 HER17_RS00725 6-phosphofructokinase low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.16 GFF820 NAD(P)HX epimerase / NAD(P)HX dehydratase 0.31 GFF2283 6-phosphofructokinase (EC 2.7.1.11) low > 78
Dyella japonica UNC79MFTsu3.2 0.15 ABZR86_RS00840 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.15 ABZR86_RS17355 6-phosphofructokinase low > 74
Klebsiella michiganensis M5al 0.15 BWI76_RS02510 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.30 BWI76_RS00735 ATP-dependent 6-phosphofructokinase — —
Magnetospirillum magneticum AMB-1 0.15 AMB_RS14075 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.33 AMB_RS11635 ATP-dependent 6-phosphofructokinase low > 64
Azospirillum sp. SherDot2 0.15 MPMX19_01552 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.30 MPMX19_01414 ATP-dependent 6-phosphofructokinase 2 low > 112
Serratia liquefaciens MT49 0.15 IAI46_01600 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 IAI46_24645 6-phosphofructokinase low > 86
Escherichia fergusonii Becca 0.15 EFB2_04368 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.31 EFB2_04702 ATP-dependent 6-phosphofructokinase isozyme 1 low > 86
Escherichia coli Nissle 1917 0.15 ECOLIN_RS24205 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 ECOLIN_RS22555 6-phosphofructokinase low > 52
Escherichia coli BW25113 0.15 b4167 yjeF predicted carbohydrate kinase (NCBI) 0.31 b3916 pfkA 6-phosphofructokinase (NCBI) low > 76
Kangiella aquimarina DSM 16071 0.15 B158DRAFT_1947 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.14 B158DRAFT_2034 6-phosphofructokinase — —
Escherichia coli ECRC98 0.15 JDDGAC_15920 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 JDDGAC_17455 pfkA 6-phosphofructokinase — —
Escherichia coli ECRC62 0.15 BNILDI_06945 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 BNILDI_05565 pfkA 6-phosphofructokinase — —
Dechlorosoma suillum PS 0.15 Dsui_2898 yjeF-like protein, hydroxyethylthiazole kinase-related protein 0.15 Dsui_3261 6-phosphofructokinase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.15 OHPLBJKB_03875 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.31 OHPLBJKB_04135 ATP-dependent 6-phosphofructokinase isozyme 1 low > 73
Escherichia coli ECOR27 0.15 NOLOHH_04545 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 NOLOHH_05965 pfkA 6-phosphofructokinase — —
Escherichia coli ECRC101 0.15 OKFHMN_12280 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 OKFHMN_13830 pfkA 6-phosphofructokinase — —
Escherichia coli ECRC102 0.15 NIAGMN_10130 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 NIAGMN_11585 pfkA 6-phosphofructokinase — —
Escherichia coli ECRC101 0.15 MCAODC_02795 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 MCAODC_04330 pfkA 6-phosphofructokinase — —
Xanthomonas campestris pv. campestris strain 8004 0.15 Xcc-8004.2253.1 NAD(P)HX epimerase / NAD(P)HX dehydratase 0.11 Xcc-8004.1104.1 hypothetical protein low > 74
Escherichia coli ECRC99 0.15 KEDOAH_15875 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 KEDOAH_14330 pfkA 6-phosphofructokinase — —
Escherichia coli ECOR38 0.14 HEPCGN_10510 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 HEPCGN_12475 pfkA 6-phosphofructokinase low > 85
Escherichia coli BL21 0.14 ECD_04034 bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehydratase and N-terminal domain NAD(P)H-hydrate epimerase 0.31 ECD_03801 6-phosphofructokinase I low > 60
Enterobacter asburiae PDN3 0.14 EX28DRAFT_3364 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.30 EX28DRAFT_4390 6-phosphofructokinase (EC 2.7.1.11) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.14 ABZR88_RS18865 NAD(P)H-hydrate dehydratase 0.30 ABZR88_RS12460 6-phosphofructokinase low > 71
Enterobacter sp. TBS_079 0.14 MPMX20_00448 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.30 MPMX20_04552 ATP-dependent 6-phosphofructokinase isozyme 1 low > 85
Vibrio cholerae E7946 ATCC 55056 0.14 CSW01_14940 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 CSW01_13575 ATP-dependent 6-phosphofructokinase — —
Erwinia tracheiphila SCR3 0.14 LU632_RS02030 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.30 LU632_RS21840 pfkA 6-phosphofructokinase — —
Azospirillum brasilense Sp245 0.13 AZOBR_RS07115 hypothetical protein 0.30 AZOBR_RS06155 6-phosphofructokinase low > 97
Synechococcus elongatus PCC 7942 0.13 Synpcc7942_1273 hypothetical protein 0.30 Synpcc7942_0592 pfkA 6-phosphofructokinase low > 38
Marinobacter adhaerens HP15 0.13 HP15_2504 carbohydrate kinase, YjeF related protein 0.14 HP15_615 6-phosphofructokinase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.12 Echvi_0073 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.32 Echvi_2380 6-phosphofructokinase low > 79
Pontibacter actiniarum KMM 6156, DSM 19842 0.12 CA264_16280 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.31 CA264_12055 6-phosphofructokinase low > 74
Rhodospirillum rubrum S1H 0.09 Rru_A1547 hypothetical protein (NCBI) 0.30 Rru_A1047 6-phosphofructokinase (NCBI) low > 58

Not shown: 42 genomes with orthologs for Rv3433c only; 5 genomes with orthologs for Rv3010c only