| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Azospirillum sp. SherDot2 | 1.0 | MPMX19_04609 | | Putative short-chain type dehydrogenase/reductase | 1.0 | MPMX19_02575 | | dITP/XTP pyrophosphatase | 0.58 | 1 |
| Rhodopseudomonas palustris CGA009 | 0.56 | TX73_011280 | | SDR family NAD(P)-dependent oxidoreductase | 0.51 | TX73_001705 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 86 |
| Burkholderia phytofirmans PsJN | 0.55 | BPHYT_RS25395 | | 3-oxoacyl-ACP reductase | 0.33 | BPHYT_RS15330 | | nucleoside-triphosphate diphosphatase | low | > 109 |
| Paraburkholderia sabiae LMG 24235 | 0.54 | QEN71_RS08260 | | SDR family NAD(P)-dependent oxidoreductase | 0.31 | QEN71_RS03640 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 153 |
| Variovorax sp. SCN45 | 0.54 | GFF7067 | | Oxidoreductase, short-chain dehydrogenase/reductase family | 0.22 | GFF2382 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66) | low | > 127 |
| Sphingomonas koreensis DSMZ 15582 | 0.53 | Ga0059261_3648 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | 0.62 | Ga0059261_2742 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | low | > 68 |
| Acidovorax sp. GW101-3H11 | 0.53 | Ac3H11_3127 | | Oxidoreductase, short chain dehydrogenase/reductase family | 0.22 | Ac3H11_3671 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | low | > 79 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.52 | A4249_RS11160 | | SDR family NAD(P)-dependent oxidoreductase | 0.50 | A4249_RS12440 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | — | — |
| Acinetobacter baumannii LAC-4 | 0.51 | RR41_RS13470 | | SDR family NAD(P)-dependent oxidoreductase | 0.28 | RR41_RS16630 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 55 |
| Variovorax sp. OAS795 | 0.51 | ABID97_RS20955 | | SDR family NAD(P)-dependent oxidoreductase | 0.23 | ABID97_RS23635 | | non-canonical purine NTP pyrophosphatase | low | > 91 |
| Caulobacter crescentus NA1000 Δfur | 0.48 | CCNA_02178 | | short-chain alcohol dehydrogenase | 0.51 | CCNA_00145 | | xanthosine triphosphate pyrophosphatase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.48 | CCNA_02178 | | short-chain alcohol dehydrogenase | 0.51 | CCNA_00145 | | xanthosine triphosphate pyrophosphatase | low | > 66 |
| Pseudomonas stutzeri RCH2 | 0.40 | Psest_3241 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | 0.30 | Psest_0277 | | non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family | low | > 67 |
| Pseudomonas syringae pv. syringae B728a | 0.40 | Psyr_1025 | | Short-chain dehydrogenase/reductase SDR | 0.30 | Psyr_0472 | | Ham1-like protein | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.40 | Psyr_1025 | | Short-chain dehydrogenase/reductase SDR | 0.30 | Psyr_0472 | | Ham1-like protein | low | > 86 |
| Mycobacterium tuberculosis H37Rv | 0.40 | Rv0148 | | Probable short-chain type dehydrogenase/reductase | 0.25 | Rv1341 | | Conserved protein | — | — |
| Pseudomonas segetis P6 | 0.40 | MPMX49_03663 | | Putative short-chain type dehydrogenase/reductase | 0.30 | MPMX49_00604 | | dITP/XTP pyrophosphatase | low | > 75 |
| Pseudomonas sp. SVBP6 | 0.40 | COO64_RS03620 | | SDR family oxidoreductase | 0.30 | COO64_RS12970 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 93 |
| Pseudomonas fluorescens FW300-N2E3 | 0.39 | AO353_15525 | | serine/threonine protein kinase | 0.30 | AO353_08195 | | non-canonical purine NTP pyrophosphatase | low | > 101 |
| Pseudomonas sp. BP01 | 0.39 | JOY50_RS15565 | | SDR family oxidoreductase | 0.31 | JOY50_RS20880 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 84 |
| Pseudomonas aeruginosa PA14 | 0.39 | IKLFDK_17595 | | serine/threonine protein kinase | 0.29 | IKLFDK_23490 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 100 |
| Pseudomonas lactucae CFBP13502 | 0.39 | GEMAOFIL_04834 | | Putative short-chain type dehydrogenase/reductase | 0.30 | GEMAOFIL_05488 | | dITP/XTP pyrophosphatase | low | > 93 |
| Pseudomonas fluorescens GW456-L13 | 0.39 | PfGW456L13_4969 | | Oxidoreductase, short chain dehydrogenase/reductase family | 0.30 | PfGW456L13_1004 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | low | > 87 |
| Pseudomonas simiae WCS417 | 0.39 | PS417_23435 | | serine/threonine protein kinase | 0.31 | PS417_26755 | | nucleoside-triphosphate diphosphatase | low | > 88 |
| Pseudomonas fluorescens SBW25 | 0.39 | PFLU_RS25265 | | SDR family oxidoreductase | 0.30 | PFLU_RS28400 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.39 | PFLU_RS25265 | | SDR family oxidoreductase | 0.30 | PFLU_RS28400 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 109 |
| Pseudomonas fluorescens FW300-N1B4 | 0.39 | Pf1N1B4_1031 | | Oxidoreductase, short chain dehydrogenase/reductase family | 0.30 | Pf1N1B4_2335 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | low | > 87 |
| Pseudomonas sp. DMC3 | 0.39 | GFF1869 | | Putative short-chain type dehydrogenase/reductase | 0.30 | GFF215 | | dITP/XTP pyrophosphatase | low | > 89 |
| Pseudomonas sp. RS175 | 0.38 | PFR28_00215 | | Putative short-chain type dehydrogenase/reductase | 0.31 | PFR28_04248 | | dITP/XTP pyrophosphatase | low | > 88 |
| Pseudomonas sp. S08-1 | 0.38 | OH686_18720 | | Oxidoreductase, short-chain dehydrogenase/reductase family | 0.31 | OH686_11015 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | low | > 80 |
| Pseudomonas fluorescens FW300-N2E2 | 0.38 | Pf6N2E2_5282 | | Oxidoreductase, short chain dehydrogenase/reductase family | 0.31 | Pf6N2E2_4594 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.38 | AO356_16785 | | serine/threonine protein kinase | 0.31 | AO356_13395 | | non-canonical purine NTP pyrophosphatase | low | > 104 |
| Sphingobium sp. HT1-2 | 0.33 | GFF4598 | | Short-chain dehydrogenase/reductase SDR | 0.61 | GFF2618 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66) | low | > 95 |
| Shewanella sp. ANA-3 | 0.32 | Shewana3_1687 | | short-chain dehydrogenase/reductase SDR (RefSeq) | 0.27 | Shewana3_1189 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) | low | > 73 |
| Castellaniella sp019104865 MT123 | 0.30 | ABCV34_RS00700 | | SDR family NAD(P)-dependent oxidoreductase | 0.27 | ABCV34_RS03520 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | low | > 48 |
| Shewanella loihica PV-4 | 0.29 | Shew_2557 | | short-chain dehydrogenase/reductase SDR (RefSeq) | 0.28 | Shew_1132 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) | — | — |
| Xanthobacter sp. DMC5 | 0.28 | GFF4816 | | 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase | 0.50 | GFF1892 | | dITP/XTP pyrophosphatase | — | — |
| Shewanella amazonensis SB2B | 0.27 | Sama_1367 | | short chain dehydrogenase/reductase family oxidoreductase (RefSeq) | 0.31 | Sama_2482 | | Ham1-like protein (RefSeq) | low | > 62 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.25 | GFF971 | | Short-chain dehydrogenase/reductase SDR | 0.24 | GFF3255 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | low | > 90 |
| Pantoea agglomerans CFBP13505 P0401 | 0.21 | PagCFBP13505_RS01435 | | SDR family NAD(P)-dependent oxidoreductase | 0.25 | PagCFBP13505_RS16110 | | XTP/dITP diphosphatase | low | > 74 |
Not shown: 0 genomes with orthologs for MPMX19_04609 only; 78 genomes with orthologs for MPMX19_02575 only