Conservation of cofitness between HER17_RS12035 and HER17_RS17885 in Pectobacterium carotovorum WPP14

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS12035 MBL fold metallo-hydrolase 1.0 HER17_RS17885 bifunctional protein-disulfide isomerase/oxidoreductase DsbC 0.58 15
Serratia liquefaciens MT49 0.81 IAI46_08745 MBL fold metallo-hydrolase 0.78 IAI46_20725 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 86
Dickeya dadantii 3937 0.78 DDA3937_RS12920 MBL fold metallo-hydrolase 0.79 DDA3937_RS03305 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 74
Dickeya dianthicola 67-19 0.78 HGI48_RS12995 MBL fold metallo-hydrolase 0.78 HGI48_RS03445 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 71
Dickeya dianthicola ME23 0.78 DZA65_RS13455 MBL fold metallo-hydrolase 0.78 DZA65_RS03490 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 75
Enterobacter sp. TBS_079 0.77 MPMX20_01585 Hydroxyacylglutathione hydrolase GloC 0.71 MPMX20_03752 Thiol:disulfide interchange protein DsbC low > 85
Enterobacter asburiae PDN3 0.77 EX28DRAFT_2009 Zn-dependent hydrolases, including glyoxylases 0.72 EX28DRAFT_2944 Protein-disulfide isomerase low > 76
Escherichia coli ECOR27 0.77 NOLOHH_21950 gloC hydroxyacylglutathione hydrolase GloC 0.68 NOLOHH_11500 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 75
Escherichia coli ECRC62 0.77 BNILDI_20205 gloC hydroxyacylglutathione hydrolase GloC 0.68 BNILDI_10030 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.77 OHPLBJKB_02740 Hydroxyacylglutathione hydrolase GloC 0.68 OHPLBJKB_00822 Thiol:disulfide interchange protein DsbC low > 73
Escherichia coli BW25113 0.76 b0927 ycbL predicted metal-binding enzyme (NCBI) 0.68 b2893 dsbC protein disulfide isomerase II (NCBI) low > 76
Escherichia coli ECOR38 0.76 HEPCGN_23135 gloC hydroxyacylglutathione hydrolase GloC 0.67 HEPCGN_18865 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 87
Escherichia coli BL21 0.76 ECD_00931 putative metal-binding enzyme 0.68 ECD_02725 protein disulfide isomerase II low > 61
Escherichia coli ECRC98 0.76 JDDGAC_09000 gloC hydroxyacylglutathione hydrolase GloC 0.68 JDDGAC_23215 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 86
Escherichia coli ECRC99 0.76 KEDOAH_22345 gloC hydroxyacylglutathione hydrolase GloC 0.68 KEDOAH_08565 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC — —
Escherichia coli Nissle 1917 0.76 ECOLIN_RS04905 hydroxyacylglutathione hydrolase GloC 0.67 ECOLIN_RS16120 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 55
Escherichia fergusonii Becca 0.76 EFB2_03137 Hydroxyacylglutathione hydrolase GloC 0.67 EFB2_01008 Thiol:disulfide interchange protein DsbC low > 86
Escherichia coli ECRC100 0.76 OKFHMN_05390 gloC hydroxyacylglutathione hydrolase GloC 0.68 OKFHMN_19575 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 80
Escherichia coli ECRC102 0.76 NIAGMN_03110 gloC hydroxyacylglutathione hydrolase GloC 0.68 NIAGMN_17340 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC — —
Escherichia coli ECRC101 0.76 MCAODC_24780 gloC hydroxyacylglutathione hydrolase GloC 0.68 MCAODC_10095 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 87
Klebsiella michiganensis M5al 0.76 BWI76_RS09865 MBL fold hydrolase 0.68 BWI76_RS23810 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF3684 Hypothetical metal-binding enzyme, YcbL homolog 0.69 GFF2990 Thiol:disulfide interchange protein DsbC low > 78
Rahnella sp. WP5 0.73 EX31_RS18150 MBL fold metallo-hydrolase 0.69 EX31_RS13475 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 89
Pantoea sp. MT58 0.72 IAI47_12770 MBL fold metallo-hydrolase 0.61 IAI47_03825 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 76
Erwinia tracheiphila SCR3 0.66 LU632_RS09895 MBL fold metallo-hydrolase 0.68 LU632_RS05980 dsbC bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 74
Shewanella amazonensis SB2B 0.62 Sama_2142 metallo-beta-lactamase family protein (RefSeq) 0.46 Sama_2738 thiol:disulfide interchange protein DsbC (RefSeq) low > 62
Shewanella oneidensis MR-1 0.61 SO3054 metallo-beta-lactamase family protein (NCBI ptt file) 0.45 SO0951 dsbC thiol:disulfide interchange protein DsbC (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.61 Shewana3_1493 beta-lactamase domain-containing protein (RefSeq) 0.45 Shewana3_3330 thiol:disulfide interchange protein DsbC (RefSeq) low > 73
Dechlorosoma suillum PS 0.60 Dsui_3107 Zn-dependent hydrolase, glyoxylase 0.15 Dsui_1091 protein-disulfide isomerase low > 51
Shewanella loihica PV-4 0.60 Shew_2269 beta-lactamase domain-containing protein (RefSeq) 0.44 Shew_0771 thiol:disulfide interchange protein DsbC (RefSeq) low > 60
Vibrio cholerae E7946 ATCC 55056 0.59 CSW01_06415 MBL fold metallo-hydrolase 0.35 CSW01_12245 bifunctional protein-disulfide isomerase/oxidoreductase DsbC low > 62
Paraburkholderia sabiae LMG 24235 0.58 QEN71_RS00645 MBL fold metallo-hydrolase 0.16 QEN71_RS27590 DsbC family protein low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.57 GFF1871 Hypothetical metal-binding enzyme, YcbL homolog 0.16 GFF624 Thiol:disulfide interchange protein DsbC low > 90
Alteromonas macleodii MIT1002 0.57 MIT1002_03450 Beta-lactamase hydrolase-like protein 0.38 MIT1002_00787 Thiol:disulfide interchange protein DsbC precursor low > 70
Paraburkholderia graminis OAS925 0.57 ABIE53_000468 hydroxyacylglutathione hydrolase 0.17 ABIE53_003648 thiol:disulfide interchange protein DsbC low > 113
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS01930 hypothetical protein 0.16 BPHYT_RS17430 thiol:disulfide interchange protein low > 109
Cupriavidus basilensis FW507-4G11 0.55 RR42_RS19750 MBL fold metallo-hydrolase 0.16 RR42_RS23895 hypothetical protein low > 128
Acidovorax sp. GW101-3H11 0.46 Ac3H11_3348 Hypothetical metal-binding enzyme, YcbL homolog 0.17 Ac3H11_4004 Thiol:disulfide interchange protein DsbC — —
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_1623 Hypothetical metal-binding enzyme, YcbL homolog 0.34 PfGW456L13_1722 Thiol:disulfide interchange protein DsbC low > 87
Pseudomonas fluorescens FW300-N1B4 0.32 Pf1N1B4_2963 Hypothetical metal-binding enzyme, YcbL homolog 0.34 Pf1N1B4_3012 Thiol:disulfide interchange protein DsbC low > 87
Pseudomonas fluorescens FW300-N2E3 0.32 AO353_15160 MBL fold metallo-hydrolase 0.33 AO353_04360 protein-disulfide isomerase low > 101
Pseudomonas stutzeri RCH2 0.32 Psest_3219 Zn-dependent hydrolases, including glyoxylases 0.34 Psest_3128 Protein-disulfide isomerase low > 67
Pseudomonas putida KT2440 0.32 PP_0772 Metallo-beta-lactamase family protein 0.35 PP_1469 Thiol:disulfide interchange protein DsbC low > 96
Pseudomonas fluorescens SBW25 0.31 PFLU_RS04625 MBL fold metallo-hydrolase 0.35 PFLU_RS24555 thioredoxin fold domain-containing protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.31 PFLU_RS04625 MBL fold metallo-hydrolase 0.35 PFLU_RS24555 thioredoxin fold domain-containing protein low > 109
Pseudomonas simiae WCS417 0.31 PS417_04560 beta-lactamase 0.35 PS417_22890 protein-disulfide isomerase — —
Pseudomonas sp. S08-1 0.29 OH686_06295 MBL-fold metallo-hydrolase superfamily 0.33 OH686_17755 Thiol:disulfide interchange protein DsbC — —

Not shown: 37 genomes with orthologs for HER17_RS12035 only; 13 genomes with orthologs for HER17_RS17885 only