Conservation of cofitness between HER17_RS04700 and HER17_RS12240 in Pectobacterium carotovorum WPP14

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS04700 glutamate 5-kinase 1.0 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 10
Rahnella sp. WP5 0.90 EX31_RS20980 glutamate 5-kinase 0.88 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.93 46
Serratia liquefaciens MT49 0.90 IAI46_04430 glutamate 5-kinase 0.87 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 86
Enterobacter sp. TBS_079 0.89 MPMX20_00927 Glutamate 5-kinase 0.82 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.94 5
Klebsiella michiganensis M5al 0.89 BWI76_RS05840 glutamate 5-kinase 0.82 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.87 26
Pantoea sp. MT58 0.89 IAI47_15120 glutamate 5-kinase 0.82 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 11
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2651 glutamate 5-kinase 0.82 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.89 10
Dickeya dianthicola 67-19 0.89 HGI48_RS16605 glutamate 5-kinase 0.91 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF4114 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.83 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 78
Escherichia coli ECRC100 0.88 OKFHMN_09675 proB Glutamate 5-kinase 0.83 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.93 46
Escherichia coli Nissle 1917 0.88 ECOLIN_RS01825 glutamate 5-kinase 0.83 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Dickeya dianthicola ME23 0.88 DZA65_RS17695 glutamate 5-kinase 0.91 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Escherichia coli ECRC62 0.88 BNILDI_00245 proB Glutamate 5-kinase 0.83 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.83 74
Escherichia coli HS(pFamp)R (ATCC 700891) 0.88 OHPLBJKB_03398 Glutamate 5-kinase 0.83 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 73
Escherichia coli ECOR27 0.88 NOLOHH_02050 proB Glutamate 5-kinase 0.83 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.95 24
Escherichia coli BL21 0.88 ECD_00239 gamma-glutamate kinase 0.83 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase 0.85 31
Erwinia tracheiphila SCR3 0.88 LU632_RS01185 proB glutamate 5-kinase 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Escherichia coli ECRC102 0.88 NIAGMN_07535 proB Glutamate 5-kinase 0.83 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli BW25113 0.88 b0242 proB gamma-glutamyl kinase (NCBI) 0.83 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.95 8
Escherichia fergusonii Becca 0.88 EFB2_03778 Glutamate 5-kinase 0.83 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli ECOR38 0.88 HEPCGN_07780 proB Glutamate 5-kinase 0.83 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 47
Escherichia coli ECRC98 0.88 JDDGAC_13300 proB Glutamate 5-kinase 0.83 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.86 26
Escherichia coli ECRC101 0.88 MCAODC_00195 proB Glutamate 5-kinase 0.83 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 19
Escherichia coli ECRC99 0.88 KEDOAH_18480 proB Glutamate 5-kinase 0.83 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Dickeya dadantii 3937 0.88 DDA3937_RS16535 glutamate 5-kinase 0.92 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.74 28
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_11575 glutamate 5-kinase 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Shewanella loihica PV-4 0.62 Shew_2848 gamma-glutamyl kinase (RefSeq) 0.65 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.99 6
Shewanella amazonensis SB2B 0.62 Sama_2516 gamma-glutamyl kinase (RefSeq) 0.64 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.93 36
Shewanella sp. ANA-3 0.59 Shewana3_0954 gamma-glutamyl kinase (RefSeq) 0.64 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.97 4
Shewanella oneidensis MR-1 0.59 SO1121 proB glutamate 5-kinase (NCBI ptt file) 0.64 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.98 15
Alteromonas macleodii MIT1002 0.33 MIT1002_04056 Glutamate 5-kinase 0.64 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB low > 70
Rhodanobacter denitrificans MT42 0.30 LRK55_RS02130 glutamate 5-kinase 0.50 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 63
Rhodanobacter denitrificans FW104-10B01 0.30 LRK54_RS02375 glutamate 5-kinase 0.49 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.56 50
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.2326.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.50 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.63 24
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_09420 proB glutamate 5-kinase 0.49 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 52
Echinicola vietnamensis KMM 6221, DSM 17526 0.28 Echvi_4033 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.46 Echvi_2457 histidinol-phosphatase 0.70 41
Lysobacter sp. OAE881 0.28 ABIE51_RS13370 glutamate 5-kinase 0.51 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 62
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS08685 glutamate 5-kinase 0.51 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.27 ABZR88_RS22170 glutamate 5-kinase 0.44 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.76 21
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS20855 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.44 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.90 37
Parabacteroides merdae CL09T00C40 0.27 HMPREF1078_RS10650 glutamate 5-kinase 0.48 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.98 9
Bacteroides ovatus ATCC 8483 0.26 BACOVA_03537 glutamate 5-kinase 0.48 BACOVA_01232 histidinol-phosphatase 0.93 35
Pontibacter actiniarum KMM 6156, DSM 19842 0.26 CA264_07725 glutamate 5-kinase 0.47 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase low > 74
Bacteroides thetaiotaomicron VPI-5482 0.25 BT3719 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.48 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.87 23
Bacteroides stercoris CC31F 0.25 HMPREF1181_RS03325 glutamate 5-kinase 0.48 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 11
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS08650 glutamate 5-kinase 0.46 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 9
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS02880 glutamate 5-kinase 0.45 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.86 17

Not shown: 53 genomes with orthologs for HER17_RS04700 only; 0 genomes with orthologs for HER17_RS12240 only