Conservation of cofitness between EX28DRAFT_3670 and EX28DRAFT_0537 in Enterobacter asburiae PDN3

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Enterobacter asburiae PDN3 1.0 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) 1.0 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.89 11
Enterobacter sp. TBS_079 0.99 MPMX20_00769 2-isopropylmalate synthase 0.97 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.91 21
Klebsiella michiganensis M5al 0.96 BWI76_RS04680 2-isopropylmalate synthase 0.86 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.89 29
Klebsiella pneumoniae MKP103 0.96 KDGMDA_12910 2-isopropylmalate synthase 0.86 KDGMDA_26105 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 95
Escherichia coli BW25113 0.94 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.92 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.96 9
Escherichia coli BL21 0.94 ECD_00076 2-isopropylmalate synthase 0.92 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase 0.92 20
Escherichia coli Nissle 1917 0.94 ECOLIN_RS00400 2-isopropylmalate synthase 0.91 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECOR27 0.94 NOLOHH_03060 2-isopropylmalate synthase 0.92 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.93 45
Escherichia coli HS(pFamp)R (ATCC 700891) 0.94 OHPLBJKB_03583 2-isopropylmalate synthase 0.92 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 74
Escherichia coli ECOR38 0.94 HEPCGN_08695 2-isopropylmalate synthase 0.92 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.97 12
Escherichia coli ECRC62 0.94 BNILDI_08550 2-isopropylmalate synthase 0.91 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 65
Escherichia fergusonii Becca 0.94 EFB2_03971 2-isopropylmalate synthase 0.91 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli ECRC99 0.94 KEDOAH_17440 2-isopropylmalate synthase 0.92 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC102 0.94 NIAGMN_08565 2-isopropylmalate synthase 0.92 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 36
Escherichia coli ECRC101 0.94 MCAODC_01230 2-isopropylmalate synthase 0.92 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.84 28
Escherichia coli ECRC100 0.94 OKFHMN_10715 2-isopropylmalate synthase 0.92 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.94 50
Escherichia coli ECRC98 0.94 JDDGAC_14310 2-isopropylmalate synthase 0.92 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.75 48
Erwinia tracheiphila HP pepo 2.2 0.86 IJEDHG_05995 leuA 2-isopropylmalate synthase 0.83 IJEDHG_19080 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.80 16
Erwinia tracheiphila SCR3 0.86 LU632_RS02880 leuA 2-isopropylmalate synthase 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.72 31
Pectobacterium carotovorum WPP14 0.86 HER17_RS03085 2-isopropylmalate synthase 0.82 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 31
Dickeya dadantii 3937 0.86 DDA3937_RS18115 2-isopropylmalate synthase 0.83 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.78 18
Dickeya dianthicola ME23 0.85 DZA65_RS19200 2-isopropylmalate synthase 0.83 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.81 30
Dickeya dianthicola 67-19 0.85 HGI48_RS18055 2-isopropylmalate synthase 0.83 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Serratia liquefaciens MT49 0.85 IAI46_03355 2-isopropylmalate synthase 0.82 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 87
Pantoea agglomerans CFBP13505 P0401 0.84 PagCFBP13505_RS13000 2-isopropylmalate synthase 0.83 PagCFBP13505_RS01200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Pantoea sp. MT58 0.84 IAI47_16000 2-isopropylmalate synthase 0.83 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.97 14
Erwinia amylovora T8 0.84 OLJFJH_01285 2-isopropylmalate synthase 0.84 OLJFJH_12170 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.88 26
Rahnella sp. WP5 0.81 EX31_RS03680 2-isopropylmalate synthase 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 5
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_12595 2-isopropylmalate synthase 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Shewanella amazonensis SB2B 0.67 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.62 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.93 29
Shewanella oneidensis MR-1 0.66 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.62 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.97 17
Shewanella sp. ANA-3 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.62 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.96 6
Shewanella loihica PV-4 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.65 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.99 1
Alteromonas macleodii MIT1002 0.61 MIT1002_00949 2-isopropylmalate synthase 0.67 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.94 35
Parabacteroides merdae CL09T00C40 0.43 HMPREF1078_RS16665 2-isopropylmalate synthase 0.46 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 16
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14545 2-isopropylmalate synthase 0.46 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 16
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10195 2-isopropylmalate synthase 0.45 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.77 28
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14150 2-isopropylmalate synthase 0.47 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 25
Bacteroides ovatus ATCC 8483 0.41 BACOVA_04604 2-isopropylmalate synthase 0.46 BACOVA_01232 histidinol-phosphatase 0.95 9
Bacteroides thetaiotaomicron VPI-5482 0.41 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.46 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.90 25
Dyella japonica UNC79MFTsu3.2 0.41 ABZR86_RS15970 2-isopropylmalate synthase 0.53 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.94 49
Rhodanobacter denitrificans MT42 0.39 LRK55_RS09985 2-isopropylmalate synthase 0.53 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.69 15
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS10345 2-isopropylmalate synthase 0.53 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.56 52
Lysobacter sp. OAE881 0.39 ABIE51_RS17570 2-isopropylmalate synthase 0.54 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.79 53
Rhodanobacter sp000427505 FW510-R12 0.39 LRK53_RS03120 2-isopropylmalate synthase 0.52 LRK53_RS08470 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 59
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_13575 leuA 2-isopropylmalate synthase 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 26
Xanthomonas campestris pv. campestris strain 8004 0.38 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.53 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.84 12

Not shown: 34 genomes with orthologs for EX28DRAFT_3670 only; 6 genomes with orthologs for EX28DRAFT_0537 only