Conservation of cofitness between ECD_00936 and ECD_04022 in Escherichia coli BL21

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00936 aminopeptidase N 1.0 ECD_04022 penicillin-binding protein; beta-lactamase, intrinsically weak 0.50 23
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02734 Aminopeptidase N 0.99 OHPLBJKB_03890 Beta-lactamase low > 73
Escherichia coli BW25113 1.00 b0932 pepN aminopeptidase N (NCBI) 0.97 b4150 ampC beta-lactamase/D-alanine carboxypeptidase (NCBI) low > 76
Escherichia coli ECOR27 1.00 NOLOHH_21920 pepN aminopeptidase N 0.99 NOLOHH_04625 blaEC BlaEC family class C beta-lactamase low > 75
Escherichia coli ECRC62 1.00 BNILDI_20175 pepN aminopeptidase N 0.98 BNILDI_06865 blaEC BlaEC family class C beta-lactamase low > 75
Escherichia coli ECRC100 0.99 OKFHMN_05365 pepN aminopeptidase N 0.99 OKFHMN_12365 blaEC BlaEC family class C beta-lactamase low > 80
Escherichia coli ECRC99 0.99 KEDOAH_22370 pepN aminopeptidase N 0.99 KEDOAH_15800 blaEC BlaEC family class C beta-lactamase — —
Escherichia coli ECRC101 0.99 MCAODC_24755 pepN aminopeptidase N 0.99 MCAODC_02875 blaEC BlaEC family class C beta-lactamase low > 87
Escherichia coli ECRC98 0.99 JDDGAC_08975 pepN aminopeptidase N 0.99 JDDGAC_16000 blaEC BlaEC family class C beta-lactamase low > 86
Escherichia coli ECRC102 0.99 NIAGMN_03085 pepN aminopeptidase N 0.99 NIAGMN_10210 blaEC BlaEC family class C beta-lactamase — —
Escherichia fergusonii Becca 0.99 EFB2_03132 Aminopeptidase N 0.95 EFB2_04383 Beta-lactamase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04935 aminopeptidase N 0.96 ECOLIN_RS24110 cephalosporin-hydrolyzing class C beta-lactamase EC-5 low > 55
Escherichia coli ECOR38 0.99 HEPCGN_23160 pepN aminopeptidase N 0.96 HEPCGN_10590 blaEC BlaEC family class C beta-lactamase low > 87
Enterobacter asburiae PDN3 0.91 EX28DRAFT_2004 aminopeptidase N, Escherichia coli type 0.74 EX28DRAFT_3350 Beta-lactamase class C and other penicillin binding proteins low > 76
Enterobacter sp. TBS_079 0.89 MPMX20_01590 Aminopeptidase N 0.74 MPMX20_00432 Beta-lactamase low > 85
Pantoea sp. MT58 0.80 IAI47_12745 aminopeptidase N 0.55 IAI47_09850 beta-lactamase low > 76
Serratia liquefaciens MT49 0.79 IAI46_08775 aminopeptidase N 0.36 IAI46_11615 beta-lactamase low > 86
Dickeya dianthicola 67-19 0.76 HGI48_RS12955 aminopeptidase N 0.09 HGI48_RS20655 serine hydrolase low > 71
Dickeya dianthicola ME23 0.76 DZA65_RS13420 aminopeptidase N 0.09 DZA65_RS21670 serine hydrolase low > 75
Shewanella sp. ANA-3 0.55 Shewana3_1779 pepN aminopeptidase N (RefSeq) 0.39 Shewana3_1990 ampC beta-lactamase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.54 SO2600 pepN aminopeptidase N (NCBI ptt file) 0.38 SO2388 beta-lactamase (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.54 Shew_1803 aminopeptidase N (RefSeq) 0.11 Shew_1968 beta-lactamase (RefSeq) low > 60
Pseudomonas fluorescens SBW25 0.49 PFLU_RS13095 aminopeptidase N 0.42 PFLU_RS16915 class C beta-lactamase low > 109
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS13095 aminopeptidase N 0.42 PFLU_RS16915 class C beta-lactamase low > 109
Pseudomonas putida KT2440 0.48 PP_2017 aminopeptidase N 0.35 PP_2876 Beta-lactamase low > 96
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_24560 aminopeptidase 0.44 AO356_01295 class C beta-lactamase low > 104
Pseudomonas fluorescens FW300-N2E3 0.48 AO353_23630 aminopeptidase 0.37 AO353_00425 class C beta-lactamase low > 101
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_604 Membrane alanine aminopeptidase N (EC 3.4.11.2) 0.44 Pf6N2E2_2130 Beta-lactamase (EC 3.5.2.6) low > 103
Pseudomonas sp. RS175 0.48 PFR28_01574 Aminopeptidase N 0.42 PFR28_01309 Beta-lactamase low > 88
Pseudomonas simiae WCS417 0.48 PS417_12395 aminopeptidase N 0.43 PS417_14895 beta-lactamase/D-alanine carboxypeptidase low > 88
Pseudomonas sp. S08-1 0.48 OH686_04270 aminopeptidase N 0.43 OH686_03730 Class C beta-lactamase low > 80
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_3325 Membrane alanine aminopeptidase N (EC 3.4.11.2) 0.43 PfGW456L13_2479 Beta-lactamase (EC 3.5.2.6) low > 87
Pseudomonas syringae pv. syringae B728a 0.47 Psyr_1690 Peptidase M1, membrane alanine aminopeptidase 0.38 Psyr_3364 Beta-lactamase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.47 Psyr_1690 Peptidase M1, membrane alanine aminopeptidase 0.38 Psyr_3364 Beta-lactamase low > 86
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_4614 Membrane alanine aminopeptidase N (EC 3.4.11.2) 0.44 Pf1N1B4_73 Beta-lactamase (EC 3.5.2.6) low > 87
Alteromonas macleodii MIT1002 0.46 MIT1002_02028 Aminopeptidase N 0.11 MIT1002_03904 Beta-lactamase precursor low > 70
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS15210 aminopeptidase N 0.40 BPHYT_RS25150 class C beta-lactamase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_03988 alanyl aminopeptidase. Metallo peptidase. MEROPS family M01 0.39 H281DRAFT_02462 beta-lactamase class C low > 103
Paraburkholderia graminis OAS925 0.42 ABIE53_003216 aminopeptidase N 0.40 ABIE53_006152 beta-lactamase class C low > 113
Sinorhizobium meliloti 1021 0.41 SMc02370 aminopeptidase N 0.43 SM_b21600 beta-lactamase low > 103
Agrobacterium fabrum C58 0.41 Atu0984 aminopeptidase N 0.38 Atu3077 beta-lactamase low > 89
Rhizobium sp. OAE497 0.41 ABIE40_RS05720 aminopeptidase N 0.38 ABIE40_RS05500 class C beta-lactamase low > 107
Rhodanobacter sp. FW510-T8 0.38 OKGIIK_13715 Aminopeptidase N 0.12 OKGIIK_12395 Serine hydrolase low > 52
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS10200 aminopeptidase N 0.12 LRK54_RS11465 serine hydrolase low > 59
Rhodanobacter denitrificans MT42 0.38 LRK55_RS09840 aminopeptidase N 0.12 LRK55_RS11195 serine hydrolase domain-containing protein low > 63
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS15770 aminopeptidase N 0.34 ABZR86_RS05110 class C beta-lactamase low > 74

Not shown: 33 genomes with orthologs for ECD_00936 only; 1 genomes with orthologs for ECD_04022 only