Conservation of cofitness between CSW01_12325 and CSW01_12340 in Vibrio cholerae E7946 ATCC 55056

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12325 dehydrogenase 1.0 CSW01_12340 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 0.43 19
Serratia liquefaciens MT49 0.49 IAI46_21935 DUF1249 family protein 0.70 IAI46_22055 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pantoea agglomerans CFBP13505 P0401 0.49 PagCFBP13505_RS11965 DUF1249 family protein 0.67 PagCFBP13505_RS11925 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pantoea sp. MT58 0.49 IAI47_03145 DUF1249 family protein 0.67 IAI47_03105 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Enterobacter sp. TBS_079 0.49 MPMX20_03880 hypothetical protein 0.69 MPMX20_03889 Bifunctional protein HldE — —
Erwinia amylovora T8 0.49 OLJFJH_07685 DUF1249 domain-containing protein 0.65 OLJFJH_07645 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3071 Uncharacterized protein conserved in bacteria 0.68 EX28DRAFT_3080 rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II — —
Rahnella sp. WP5 0.48 EX31_RS25980 DUF1249 family protein 0.69 EX31_RS08140 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE low > 89
Pectobacterium carotovorum WPP14 0.48 HER17_RS19815 DUF1249 family protein 0.70 HER17_RS04040 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Klebsiella michiganensis M5al 0.48 BWI76_RS24390 hypothetical protein 0.68 BWI76_RS24455 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase — —
Klebsiella pneumoniae MKP103 0.48 KDGMDA_05215 DUF1249 domain-containing protein 0.68 KDGMDA_05265 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.47 GFF3147 FIG074102: hypothetical protein 0.69 GFF3166 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase low > 78
Escherichia coli BL21 0.47 ECD_02905 DUF1249 protein YqiB 0.69 ECD_02922 heptose 7-phosphate kinase and heptose 1-phosphate adenyltransferase — —
Escherichia coli ECRC62 0.47 BNILDI_00895 yqiB DUF1249 domain-containing protein 0.69 BNILDI_00995 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Escherichia coli BW25113 0.47 b3033 yqiB predicted dehydrogenase (NCBI) 0.69 b3052 rfaE fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) low > 76
Escherichia coli ECOR27 0.47 NOLOHH_10620 yqiB DUF1249 domain-containing protein 0.69 NOLOHH_10520 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Escherichia coli ECRC100 0.47 OKFHMN_18815 yqiB DUF1249 domain-containing protein 0.69 OKFHMN_18735 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Escherichia coli ECOR38 0.47 HEPCGN_17690 yqiB DUF1249 domain-containing protein 0.69 HEPCGN_17590 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Escherichia coli Nissle 1917 0.47 ECOLIN_RS17505 DUF1249 family protein 0.69 ECOLIN_RS17615 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE low > 55
Escherichia coli ECRC102 0.47 NIAGMN_16580 yqiB DUF1249 domain-containing protein 0.69 NIAGMN_16500 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.47 OHPLBJKB_00670 hypothetical protein 0.69 OHPLBJKB_00652 Bifunctional protein HldE — —
Escherichia coli ECRC99 0.47 KEDOAH_09330 yqiB DUF1249 domain-containing protein 0.69 KEDOAH_09410 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Escherichia coli ECRC101 0.47 MCAODC_09330 yqiB DUF1249 domain-containing protein 0.69 MCAODC_09250 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Escherichia fergusonii Becca 0.47 EFB2_00775 hypothetical protein 0.69 EFB2_00759 Bifunctional protein HldE — —
Escherichia coli ECRC98 0.47 JDDGAC_22450 yqiB DUF1249 domain-containing protein 0.69 JDDGAC_22370 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Dickeya dianthicola 67-19 0.47 HGI48_RS01645 DUF1249 family protein 0.68 HGI48_RS17150 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Dickeya dianthicola ME23 0.46 DZA65_RS01720 DUF1249 family protein 0.68 DZA65_RS18235 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Dickeya dadantii 3937 0.45 DDA3937_RS01750 DUF1249 family protein 0.68 DDA3937_RS17100 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas sp. DMC3 0.37 GFF3187 hypothetical protein 0.57 GFF3175 Bifunctional protein HldE — —
Pseudomonas segetis P6 0.36 ACVTMO_RS20735 DUF1249 domain-containing protein 0.59 ACVTMO_RS20805 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_13030 cytoplasmic protein 0.57 AO353_12970 heptose 1-phosphate adenyltransferase — —
Pseudomonas aeruginosa PUPa3 0.36 DQ20_RS51415 DUF1249 domain-containing protein 0.58 DQ20_RS51275 hldE;go_function=nucleotidyltransferase bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas aeruginosa MRSN321 0.36 DY961_RS10645 DUF1249 domain-containing protein 0.58 DY961_RS10785 hldE;go_function=nucleotidyltransferase bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_181 FIG074102: hypothetical protein 0.57 PfGW456L13_195 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase — —
Pseudomonas aeruginosa PA14 0.35 IKLFDK_28690 DUF1249 domain-containing protein 0.58 IKLFDK_28555 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_3640 FIG074102: hypothetical protein 0.57 Pf6N2E2_3653 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase — —
Pseudomonas sp. RS175 0.35 PFR28_05095 hypothetical protein 0.57 PFR28_05083 Bifunctional protein HldE — —
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_1443 FIG074102: hypothetical protein 0.57 Pf1N1B4_1455 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase — —
Pseudomonas fluorescens FW300-N2C3 0.35 AO356_08790 cytoplasmic protein 0.57 AO356_08850 heptose 1-phosphate adenyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.34 PFLU_RS02450 DUF1249 domain-containing protein 0.58 PFLU_RS02385 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas fluorescens SBW25 0.34 PFLU_RS02450 DUF1249 domain-containing protein 0.58 PFLU_RS02385 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas lactucae CFBP13502 0.34 GEMAOFIL_00712 hypothetical protein 0.58 GEMAOFIL_00699 Bifunctional protein HldE — —
Pseudomonas orientalis W4I3 0.34 QF045_RS05435 DUF1249 domain-containing protein 0.58 QF045_RS05375 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas sp. S08-1 0.34 OH686_15830 Uncharacterized protein YqiB 0.58 OH686_09595 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase / D-glycero-beta-D-manno-heptose-7-phosphate kinase — —
Pseudomonas simiae WCS417 0.34 PS417_02375 hypothetical protein 0.58 PS417_02310 heptose 1-phosphate adenyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.34 Psyr_0548 Protein of unknown function DUF1249 0.57 Psyr_0537 D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.34 Psyr_0548 Protein of unknown function DUF1249 0.57 Psyr_0537 D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase — —
Pseudomonas stutzeri RCH2 0.33 Psest_0480 Uncharacterized protein conserved in bacteria 0.59 Psest_0470 rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II — —
Pseudomonas sp. BP01 0.33 JOY50_RS17110 DUF1249 domain-containing protein 0.58 JOY50_RS10025 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas sp. SVBP6 0.33 COO64_RS17775 DUF1249 domain-containing protein 0.57 COO64_RS17715 hldE bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE — —
Pseudomonas putida KT2440 0.33 PP_4918 conserved protein of unknown function 0.56 PP_4934 heptose 7-phosphate kinase/heptose 1-phosphate adenylyltransferase — —
Kangiella aquimarina DSM 16071 0.27 B158DRAFT_0976 Uncharacterized protein conserved in bacteria 0.55 B158DRAFT_1987 D-alpha,beta-D-heptose 7-phosphate 1-kinase (EC 2.7.1.167)/D-beta-D-heptose 1-phosphate adenylyltransferase (EC 2.7.7.70) low > 40
Shewanella sp. ANA-3 0.26 Shewana3_0727 hypothetical protein (RefSeq) 0.65 Shewana3_0849 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.25 SO3902 conserved hypothetical protein (NCBI ptt file) 0.64 SO3745 rfaE ADP-heptose synthase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.24 Sama_3046 hypothetical protein (RefSeq) 0.61 Sama_0731 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) — —
Shewanella loihica PV-4 0.24 Shew_0546 hypothetical protein (RefSeq) 0.63 Shew_0659 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) low > 60

Not shown: 2 genomes with orthologs for CSW01_12325 only; 12 genomes with orthologs for CSW01_12340 only