| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_00595 | | heme biosynthesis protein HemY | 1.0 | CSW01_01875 | | hypothetical protein | 0.74 | 16 |
| Rahnella sp. WP5 | 0.28 | EX31_RS15130 | | protoheme IX biogenesis protein HemY | 0.66 | EX31_RS04470 | | transcriptional regulator | low | > 89 |
| Escherichia coli ECOR38 | 0.27 | HEPCGN_13185 | hemY | protoheme IX biogenesis protein HemY | 0.64 | HEPCGN_16130 | yheO | Uncharacterized protein YheO | low | > 87 |
| Escherichia coli ECRC101 | 0.27 | MCAODC_04970 | hemY | protoheme IX biogenesis protein HemY | 0.64 | MCAODC_07830 | yheO | Uncharacterized protein YheO | low | > 87 |
| Escherichia coli BW25113 | 0.27 | b3802 | hemY | predicted protoheme IX synthesis protein (NCBI) | 0.64 | b3346 | yheO | orf, hypothetical protein (VIMSS) | low | > 76 |
| Escherichia coli ECRC100 | 0.27 | OKFHMN_14465 | hemY | protoheme IX biogenesis protein HemY | 0.64 | OKFHMN_17300 | yheO | Uncharacterized protein YheO | low | > 80 |
| Escherichia coli BL21 | 0.27 | ECD_03677 | | putative protoheme IX synthesis protein | 0.64 | ECD_03197 | | putative PAS domain-containing DNA-binding transcriptional regulator | low | > 61 |
| Escherichia coli ECRC99 | 0.27 | KEDOAH_13685 | hemY | protoheme IX biogenesis protein HemY | 0.64 | KEDOAH_10840 | yheO | Uncharacterized protein YheO | — | — |
| Escherichia coli ECRC102 | 0.27 | NIAGMN_12220 | hemY | protoheme IX biogenesis protein HemY | 0.64 | NIAGMN_15070 | yheO | Uncharacterized protein YheO | — | — |
| Escherichia fergusonii Becca | 0.27 | EFB2_04836 | | Protein HemY | 0.64 | EFB2_00477 | | Transcriptional regulator DauR | low | > 86 |
| Escherichia coli ECOR27 | 0.27 | NOLOHH_06610 | hemY | protoheme IX biogenesis protein HemY | 0.64 | NOLOHH_09100 | yheO | Uncharacterized protein YheO | low | > 75 |
| Escherichia coli ECRC98 | 0.27 | JDDGAC_18090 | hemY | protoheme IX biogenesis protein HemY | 0.64 | JDDGAC_20930 | yheO | Uncharacterized protein YheO | low | > 86 |
| Escherichia coli ECRC62 | 0.27 | BNILDI_04925 | hemY | protoheme IX biogenesis protein HemY | 0.64 | BNILDI_02420 | yheO | Uncharacterized protein YheO | low | > 75 |
| Escherichia coli Nissle 1917 | 0.27 | ECOLIN_RS21820 | | protoheme IX biogenesis protein HemY | 0.64 | ECOLIN_RS19165 | | transcriptional regulator | low | > 55 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.27 | OHPLBJKB_04251 | | Protein HemY | 0.64 | OHPLBJKB_00357 | | Transcriptional regulator DauR | low | > 73 |
| Enterobacter asburiae PDN3 | 0.26 | EX28DRAFT_4471 | | heme biosynthesis-associated TPR protein | 0.64 | EX28DRAFT_4184 | | Uncharacterized protein conserved in bacteria | low | > 76 |
| Klebsiella michiganensis M5al | 0.26 | BWI76_RS01165 | | protoheme IX biogenesis protein HemY | 0.64 | BWI76_RS25905 | | hypothetical protein | low | > 92 |
| Serratia liquefaciens MT49 | 0.26 | IAI46_00680 | | protoheme IX biogenesis protein HemY | 0.66 | IAI46_23490 | | transcriptional regulator | low | > 86 |
| Pantoea sp. MT58 | 0.26 | IAI47_18440 | | protoheme IX biogenesis protein HemY | 0.65 | IAI47_02055 | | transcriptional regulator | low | > 76 |
| Enterobacter sp. TBS_079 | 0.26 | MPMX20_04473 | | Protein HemY | 0.64 | MPMX20_04239 | | Transcriptional regulator DauR | low | > 85 |
| Dickeya dadantii 3937 | 0.25 | DDA3937_RS19935 | | protoheme IX biogenesis protein HemY | 0.66 | DDA3937_RS19340 | | transcriptional regulator | low | > 74 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.24 | GFF226 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.64 | GFF3726 | | YheO-like PAS domain | low | > 78 |
| Erwinia tracheiphila SCR3 | 0.24 | LU632_RS24175 | hemY | protoheme IX biogenesis protein HemY | 0.66 | LU632_RS22710 | | transcriptional regulator | low | > 74 |
| Erwinia amylovora T8 | 0.24 | OLJFJH_06375 | | protoheme IX biogenesis protein HemY | 0.66 | OLJFJH_03930 | | Uncharacterized protein YheO | low | > 58 |
| Pectobacterium carotovorum WPP14 | 0.24 | HER17_RS01300 | | protoheme IX biogenesis protein HemY | 0.65 | HER17_RS02010 | | transcriptional regulator | low | > 75 |
| Dickeya dianthicola 67-19 | 0.24 | HGI48_RS20090 | | protoheme IX biogenesis protein HemY | 0.66 | HGI48_RS19440 | | transcriptional regulator | 0.43 | 40 |
| Dickeya dianthicola ME23 | 0.24 | DZA65_RS21135 | | protoheme IX biogenesis protein HemY | 0.66 | DZA65_RS20560 | | transcriptional regulator | low | > 75 |
| Pseudomonas sp. SVBP6 | 0.16 | COO64_RS01180 | | heme biosynthesis protein HemY | 0.15 | COO64_RS25095 | | transcriptional regulator | low | > 93 |
| Pseudomonas fluorescens FW300-N2C3 | 0.15 | AO356_12800 | | heme biosynthesis protein HemY | 0.14 | AO356_17355 | | hypothetical protein | low | > 104 |
| Pseudomonas fluorescens SBW25-INTG | 0.15 | PFLU_RS29195 | | heme biosynthesis protein HemY | 0.15 | PFLU_RS13585 | | DNA-binding protein | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.15 | PFLU_RS29195 | | heme biosynthesis protein HemY | 0.15 | PFLU_RS13585 | | DNA-binding protein | low | > 109 |
| Pseudomonas simiae WCS417 | 0.15 | PS417_27515 | | heme biosynthesis protein HemY | 0.15 | PS417_12915 | | DNA-binding protein | low | > 88 |
| Pseudomonas fluorescens FW300-N2E3 | 0.15 | AO353_08975 | | heme biosynthesis protein HemY | 0.16 | AO353_04640 | | hypothetical protein | low | > 101 |
| Pseudomonas fluorescens FW300-N2E2 | 0.15 | Pf6N2E2_4433 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.14 | Pf6N2E2_5396 | | YheO-like PAS domain | low | > 103 |
| Pseudomonas sp. DMC3 | 0.15 | GFF355 | | Protein HemY | 0.15 | GFF1929 | | Transcriptional regulator DauR | low | > 89 |
| Pseudomonas sp. BP01 | 0.15 | JOY50_RS18735 | | heme biosynthesis protein HemY | 0.16 | JOY50_RS24520 | | transcriptional regulator | low | > 84 |
| Pseudomonas putida KT2440 | 0.15 | PP_0189 | | putative heme biosynthesis protein | 0.16 | PP_2931 | | conserved protein of unknown function | low | > 96 |
| Pseudomonas fluorescens GW456-L13 | 0.14 | PfGW456L13_859 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.16 | PfGW456L13_1693 | | YheO-like PAS domain | low | > 87 |
| Pseudomonas sp. RS175 | 0.14 | PFR28_04363 | | Protein HemY | 0.13 | PFR28_03547 | | Transcriptional regulator DauR | low | > 88 |
| Pseudomonas aeruginosa PA14 | 0.13 | IKLFDK_27170 | | heme biosynthesis protein HemY | 0.15 | IKLFDK_19905 | | Transcriptional regulator DauR | low | > 101 |
| Pseudomonas fluorescens FW300-N1B4 | 0.13 | Pf1N1B4_2188 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.15 | Pf1N1B4_923 | | YheO-like PAS domain | — | — |
| Shewanella oneidensis MR-1 | 0.12 | SO4316 | | hemY protein, putative (NCBI ptt file) | 0.35 | SO1402 | | conserved hypothetical protein (NCBI ptt file) | low | > 76 |
| Pseudomonas sp. S08-1 | 0.11 | OH686_13915 | | Uncharacterized protein EC-HemY in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.14 | OH686_07030 | | YheO-like PAS domain | low | > 80 |
| Shewanella sp. ANA-3 | 0.11 | Shewana3_0383 | | HemY domain-containing protein (RefSeq) | 0.35 | Shewana3_2973 | | YheO domain-containing protein (RefSeq) | low | > 73 |
| Paraburkholderia sabiae LMG 24235 | 0.08 | QEN71_RS24940 | | heme biosynthesis protein HemY | 0.15 | QEN71_RS18565 | | PAS domain-containing protein | low | > 153 |
| Herbaspirillum seropedicae SmR1 | 0.08 | HSERO_RS14650 | | porphyrin biosynthesis protein | 0.14 | HSERO_RS01425 | | DNA-binding protein | — | — |
| Paraburkholderia graminis OAS925 | 0.08 | ABIE53_001317 | | HemY protein | 0.12 | ABIE53_005722 | | putative transcriptional regulator YheO | low | > 113 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.08 | H281DRAFT_00200 | | HemY protein | 0.12 | H281DRAFT_05884 | | Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains | — | — |
| Burkholderia phytofirmans PsJN | 0.08 | BPHYT_RS05240 | | heme biosynthesis protein HemY | 0.13 | BPHYT_RS28105 | | hypothetical protein | — | — |
Not shown: 9 genomes with orthologs for CSW01_00595 only; 12 genomes with orthologs for CSW01_01875 only