Conservation of cofitness between BWI76_RS25160 and BWI76_RS18935 in Klebsiella michiganensis M5al

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS25160 transcription elongation factor GreA 1.0 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.24 18
Enterobacter asburiae PDN3 0.98 EX28DRAFT_3232 transcription elongation factor GreA 0.86 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 76
Enterobacter sp. TBS_079 0.98 MPMX20_04085 Transcription elongation factor GreA 0.86 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF2922 Transcription elongation factor GreA 0.87 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 78
Escherichia coli ECOR38 0.97 HEPCGN_16920 greA transcription elongation factor GreA 0.88 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 87
Escherichia coli ECRC62 0.97 BNILDI_01690 greA transcription elongation factor GreA 0.88 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Escherichia coli BW25113 0.97 b3181 greA transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) 0.89 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) low > 76
Escherichia coli ECRC99 0.97 KEDOAH_10105 greA transcription elongation factor GreA 0.88 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECOR27 0.97 NOLOHH_09845 greA transcription elongation factor GreA 0.88 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Escherichia coli ECRC100 0.97 OKFHMN_18045 greA transcription elongation factor GreA 0.88 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 80
Escherichia coli Nissle 1917 0.97 ECOLIN_RS18320 transcription elongation factor GreA 0.88 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC102 0.97 NIAGMN_15805 greA transcription elongation factor GreA 0.88 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia fergusonii Becca 0.97 EFB2_00642 Transcription elongation factor GreA 0.88 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli BL21 0.97 ECD_03046 transcript cleavage factor 0.88 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase low > 61
Escherichia coli ECRC98 0.97 JDDGAC_21670 greA transcription elongation factor GreA 0.88 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_00519 Transcription elongation factor GreA 0.88 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 73
Escherichia coli ECRC101 0.97 MCAODC_08565 greA transcription elongation factor GreA 0.88 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 87
Pectobacterium carotovorum WPP14 0.92 HER17_RS18330 transcription elongation factor GreA 0.83 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Dickeya dadantii 3937 0.89 DDA3937_RS03015 transcription elongation factor GreA 0.82 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Serratia liquefaciens MT49 0.89 IAI46_01880 transcription elongation factor GreA 0.84 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 86
Rahnella sp. WP5 0.89 EX31_RS08595 transcription elongation factor GreA 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 89
Dickeya dianthicola 67-19 0.89 HGI48_RS03185 transcription elongation factor GreA 0.81 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Dickeya dianthicola ME23 0.89 DZA65_RS03180 transcription elongation factor GreA 0.82 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Pantoea sp. MT58 0.86 IAI47_17080 transcription elongation factor GreA 0.81 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 76
Erwinia tracheiphila SCR3 0.78 LU632_RS21165 greA transcription elongation factor GreA 0.81 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Alteromonas macleodii MIT1002 0.77 MIT1002_01468 Transcript cleavage factor GreA 0.65 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB low > 70
Shewanella sp. ANA-3 0.73 Shewana3_1017 transcription elongation factor GreA (RefSeq) 0.62 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.73 SO1191 greA transcription elongation factor GreA (NCBI ptt file) 0.62 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.72 Sama_0951 GreA/GreB family elongation factor (RefSeq) 0.63 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) low > 62
Shewanella loihica PV-4 0.71 Shew_2837 transcription elongation factor GreA (RefSeq) 0.65 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) low > 60
Xanthomonas campestris pv. campestris strain 8004 0.62 Xcc-8004.2911.1 Transcription elongation factor GreA 0.52 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 74
Vibrio cholerae E7946 ATCC 55056 0.61 CSW01_03330 transcription elongation factor GreA 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Lysobacter sp. OAE881 0.61 ABIE51_RS11610 transcription elongation factor GreA 0.53 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 62
Rhodanobacter sp. FW510-T8 0.50 OKGIIK_07290 greA transcription elongation factor GreA 0.49 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 52
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS05595 transcription elongation factor GreA 0.50 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Rhodanobacter denitrificans MT42 0.48 LRK55_RS17860 transcription elongation factor GreA 0.50 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 63
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS18005 transcription elongation factor GreA 0.49 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 59
Phocaeicola dorei CL03T12C01 0.40 ABI39_RS04145 transcription elongation factor GreA 0.44 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 72
Phocaeicola vulgatus CL09T03C04 0.40 HMPREF1058_RS12565 transcription elongation factor GreA 0.44 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Parabacteroides merdae CL09T00C40 0.39 HMPREF1078_RS17725 transcription elongation factor GreA 0.46 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.86 37
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS00130 transcription elongation factor GreA 0.44 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Bacteroides ovatus ATCC 8483 0.38 BACOVA_01643 prokaryotic transcription elongation factor, GreA/GreB domain protein 0.46 BACOVA_01232 histidinol-phosphatase low > 94
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS23190 transcription elongation factor GreA 0.42 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase low > 88
Bacteroides thetaiotaomicron VPI-5482 0.37 BT2565 transcription elongation factor greA (NCBI ptt file) 0.47 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) — —
Bacteroides stercoris CC31F 0.37 HMPREF1181_RS00805 transcription elongation factor GreA 0.46 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.36 Echvi_0180 transcription elongation factor GreA 0.46 Echvi_2457 histidinol-phosphatase low > 79
Pontibacter actiniarum KMM 6156, DSM 19842 0.34 CA264_03870 transcription elongation factor GreA 0.46 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase low > 74

Not shown: 51 genomes with orthologs for BWI76_RS25160 only; 0 genomes with orthologs for BWI76_RS18935 only