Conservation of cofitness between BWI76_RS10890 and BWI76_RS13260 in Klebsiella michiganensis M5al

40 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS10890 glyoxylate/hydroxypyruvate reductase A 1.0 BWI76_RS13260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.21 11
Enterobacter sp. TBS_079 0.80 MPMX20_01715 Glyoxylate/hydroxypyruvate reductase A 0.96 MPMX20_02209 S-(hydroxymethyl)glutathione dehydrogenase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.79 GFF3313 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.92 GFF2617 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 78
Enterobacter asburiae PDN3 0.79 EX28DRAFT_1896 Phosphoglycerate dehydrogenase and related dehydrogenases 0.95 EX28DRAFT_1257 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Escherichia fergusonii Becca 0.77 EFB2_02940 Glyoxylate/hydroxypyruvate reductase A 0.80 EFB2_03694 S-(hydroxymethyl)glutathione dehydrogenase 0.31 51
Escherichia coli ECOR27 0.77 NOLOHH_21410 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 NOLOHH_01650 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 75
Escherichia coli BW25113 0.77 b1033 ycdW putative dehydrogenase (VIMSS) 0.80 b0356 frmA alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.77 OHPLBJKB_02633 Glyoxylate/hydroxypyruvate reductase A 0.80 OHPLBJKB_03314 S-(hydroxymethyl)glutathione dehydrogenase low > 73
Escherichia coli ECRC62 0.77 BNILDI_19570 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 BNILDI_23065 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 75
Escherichia coli BL21 0.77 ECD_01030 glyoxylate/hydroxypyruvate reductase A 0.80 ECD_00310 alcohol dehydrogenase class III; glutathione-dependent formaldehyde dehydrogenase low > 61
Escherichia coli ECRC102 0.76 NIAGMN_23950 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 NIAGMN_06795 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECRC98 0.76 JDDGAC_07540 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 JDDGAC_12395 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 86
Escherichia coli ECRC101 0.76 MCAODC_23240 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 MCAODC_27970 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 87
Escherichia coli ECRC100 0.76 OKFHMN_03880 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 OKFHMN_08740 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 80
Escherichia coli ECRC99 0.76 KEDOAH_23875 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 KEDOAH_19230 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECOR38 0.76 HEPCGN_23610 ghrA glyoxylate/hydroxypyruvate reductase GhrA 0.80 HEPCGN_07365 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 87
Escherichia coli Nissle 1917 0.76 ECOLIN_RS06000 glyoxylate/hydroxypyruvate reductase GhrA 0.80 ECOLIN_RS02210 S-(hydroxymethyl)glutathione dehydrogenase — —
Pantoea sp. MT58 0.60 IAI47_11750 glyoxylate/hydroxypyruvate reductase GhrA 0.80 IAI47_06705 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Serratia liquefaciens MT49 0.56 IAI46_09955 glyoxylate/hydroxypyruvate reductase GhrA 0.80 IAI46_07885 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.35 81
Rahnella sp. WP5 0.52 EX31_RS17370 glyoxylate/hydroxypyruvate reductase GhrA 0.80 EX31_RS18715 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 89
Burkholderia phytofirmans PsJN 0.48 BPHYT_RS02135 glyoxylate reductase 0.82 BPHYT_RS00510 S-(hydroxymethyl)glutathione dehydrogenase low > 109
Paraburkholderia graminis OAS925 0.48 ABIE53_000574 glyoxylate/hydroxypyruvate reductase A 0.66 ABIE53_003402 S-(hydroxymethyl)glutathione dehydrogenase/alcohol dehydrogenase low > 113
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS01065 glyoxylate/hydroxypyruvate reductase A 0.65 QEN71_RS02555 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_02100 glyoxylate/hydroxypyruvate reductase A 0.66 H281DRAFT_04166 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase low > 103
Ralstonia solanacearum PSI07 0.45 RPSI07_RS22875 glyoxylate/hydroxypyruvate reductase A 0.67 RPSI07_RS20965 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 81
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS00950 glyoxylate reductase 0.67 RR42_RS25775 alcohol dehydrogenase — —
Ralstonia solanacearum GMI1000 0.43 RS_RS01285 glyoxylate/hydroxypyruvate reductase A 0.67 RS_RS03030 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS06255 glyoxylate/hydroxypyruvate reductase A 0.67 ABZR87_RS08285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.33 24
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS10440 glyoxylate/hydroxypyruvate reductase A 0.68 RALBFv3_RS12345 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Ralstonia solanacearum UW163 0.42 UW163_RS03140 glyoxylate/hydroxypyruvate reductase A 0.68 UW163_RS01260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase — —
Acidovorax sp. GW101-3H11 0.41 Ac3H11_3017 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.83 Ac3H11_3163 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.40 GFF1710 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.66 GFF3318 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 90
Variovorax sp. OAS795 0.40 ABID97_RS25105 glyoxylate/hydroxypyruvate reductase A 0.66 ABID97_RS10235 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 91
Variovorax sp. SCN45 0.39 GFF2017 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.66 GFF2941 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 127
Azospirillum sp. SherDot2 0.36 MPMX19_00078 Glyoxylate/hydroxypyruvate reductase A 0.71 MPMX19_05326 S-(hydroxymethyl)glutathione dehydrogenase low > 112
Azospirillum brasilense Sp245 0.36 AZOBR_RS03790 D-2-hydroxyacid dehydrogenase 0.75 AZOBR_RS16515 S-(hydroxymethyl)glutathione dehydrogenase low > 97
Castellaniella sp019104865 MT123 0.35 ABCV34_RS06730 glyoxylate/hydroxypyruvate reductase A 0.78 ABCV34_RS09045 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Marinobacter adhaerens HP15 0.33 HP15_3938 D-isomer specific 2-hydroxyacid dehydrogenase family protein 0.78 HP15_4017 formaldehyde dehydrogenase (glutathione-dependent) low > 73
Rhodospirillum rubrum S1H 0.32 Rru_A2002 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (NCBI) 0.76 Rru_A3405 Formaldehyde dehydrogenase (glutathione) (NCBI) low > 58
Lysobacter sp. OAE881 0.30 ABIE51_RS10035 glyoxylate/hydroxypyruvate reductase A 0.84 ABIE51_RS18925 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 62
Phaeobacter inhibens DSM 17395 0.25 PGA1_c26570 putative glyoxylate/hydroxypyruvate reductase A 0.63 PGA1_c02510 S-(hydroxymethyl)glutathione dehydrogenase FrmA 0.25 14

Not shown: 0 genomes with orthologs for BWI76_RS10890 only; 45 genomes with orthologs for BWI76_RS13260 only