Conservation of cofitness between BWI76_RS04665 and BWI76_RS01655 in Klebsiella michiganensis M5al

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 1.0 BWI76_RS01655 homoserine O-succinyltransferase 0.95 9
Enterobacter sp. TBS_079 0.93 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.94 MPMX20_00230 Homoserine O-succinyltransferase 0.93 7
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.95 GFF1350 Homoserine O-succinyltransferase (EC 2.3.1.46) low > 78
Enterobacter asburiae PDN3 0.92 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.93 EX28DRAFT_4331 homoserine O-succinyltransferase (EC 2.3.1.46) 0.82 11
Escherichia coli ECRC62 0.88 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 0.94 BNILDI_06100 metA homoserine O-succinyltransferase 0.94 23
Escherichia coli BW25113 0.88 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.95 b4013 metA homoserine O-succinyltransferase (NCBI) 0.86 53
Escherichia coli ECOR27 0.88 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 0.94 NOLOHH_05420 metA homoserine O-succinyltransferase 0.93 6
Escherichia coli BL21 0.88 ECD_00073 3-isopropylmalate dehydratase small subunit 0.94 ECD_03885 homoserine O-transsuccinylase 0.74 49
Escherichia coli HS(pFamp)R (ATCC 700891) 0.88 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 0.94 OHPLBJKB_04037 Homoserine O-succinyltransferase low > 73
Escherichia coli ECOR38 0.88 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.94 HEPCGN_11915 metA homoserine O-succinyltransferase 0.90 30
Escherichia coli Nissle 1917 0.88 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 0.94 ECOLIN_RS25515 homoserine O-succinyltransferase — —
Escherichia fergusonii Becca 0.88 EFB2_03974 3-isopropylmalate dehydratase small subunit 0.94 EFB2_04597 Homoserine O-succinyltransferase low > 86
Escherichia coli ECRC99 0.87 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 0.94 KEDOAH_14885 metA homoserine O-succinyltransferase — —
Escherichia coli ECRC102 0.87 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 0.94 NIAGMN_11025 metA homoserine O-succinyltransferase — —
Escherichia coli ECRC98 0.87 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 0.94 JDDGAC_16900 metA homoserine O-succinyltransferase 0.99 1
Escherichia coli ECRC100 0.87 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 0.94 OKFHMN_13275 metA homoserine O-succinyltransferase 0.86 66
Escherichia coli ECRC101 0.87 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 0.94 MCAODC_03775 metA homoserine O-succinyltransferase 0.96 10
Rahnella sp. WP5 0.84 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.82 EX31_RS11735 homoserine O-succinyltransferase 0.97 2
Serratia liquefaciens MT49 0.84 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.83 IAI46_23200 homoserine O-succinyltransferase low > 86
Dickeya dianthicola ME23 0.84 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.83 DZA65_RS20275 homoserine O-succinyltransferase 0.87 8
Dickeya dadantii 3937 0.84 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.83 DDA3937_RS19065 homoserine O-succinyltransferase 0.72 25
Pectobacterium carotovorum WPP14 0.84 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.85 HER17_RS02285 homoserine O-succinyltransferase 0.97 11
Dickeya dianthicola 67-19 0.83 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.83 HGI48_RS19155 homoserine O-succinyltransferase 0.72 41
Pantoea sp. MT58 0.83 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.84 IAI47_18015 homoserine O-succinyltransferase 0.96 14
Erwinia tracheiphila SCR3 0.74 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.85 LU632_RS22410 metA homoserine O-succinyltransferase 0.78 15
Vibrio cholerae E7946 ATCC 55056 0.73 CSW01_12610 3-isopropylmalate dehydratase small subunit 0.66 CSW01_08100 homoserine O-succinyltransferase low > 62
Shewanella loihica PV-4 0.63 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.56 Shew_2551 homoserine O-succinyltransferase (RefSeq) 0.90 46
Alteromonas macleodii MIT1002 0.62 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.56 MIT1002_01112 Homoserine O-succinyltransferase 0.95 24
Shewanella amazonensis SB2B 0.60 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.56 Sama_1374 homoserine O-succinyltransferase (RefSeq) 0.98 5
Shewanella oneidensis MR-1 0.60 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.55 SO1676 metA homoserine O-succinyltransferase (NCBI ptt file) 0.96 19
Shewanella sp. ANA-3 0.59 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.55 Shewana3_2772 homoserine O-succinyltransferase (RefSeq) 0.96 6
Paraburkholderia sabiae LMG 24235 0.58 QEN71_RS17615 3-isopropylmalate dehydratase small subunit 0.35 QEN71_RS42530 homoserine O-succinyltransferase low > 153
Dinoroseobacter shibae DFL-12 0.51 Dshi_0083 3-isopropylmalate dehydratase, small subunit (RefSeq) 0.39 Dshi_1593 Homoserine O-succinyltransferase (RefSeq) — —
Azospirillum brasilense Sp245 0.50 AZOBR_RS14135 isopropylmalate isomerase 0.38 AZOBR_RS14010 homoserine O-succinyltransferase low > 97
Agrobacterium fabrum C58 0.49 Atu2790 3-isopropylmalate dehydratase, small subunit 0.44 Atu2718 homoserine O-succinyltransferase 0.94 5
Phaeobacter inhibens DSM 17395 0.49 PGA1_c29790 3-isopropylmalate dehydratase small subunit 0.42 PGA1_c14560 homoserine O-succinyltransferase MetA 0.74 42
Sinorhizobium meliloti 1021 0.49 SMc03795 isopropylmalate isomerase small subunit 0.42 SMc03797 homoserine O-succinyltransferase 0.94 9
Rhizobium sp. OAE497 0.48 ABIE40_RS19040 3-isopropylmalate dehydratase small subunit 0.43 ABIE40_RS18590 homoserine O-succinyltransferase 0.98 3
Bifidobacterium breve UCC2003 0.43 BBR_RS19625 3-isopropylmalate dehydratase small subunit 0.41 BBR_RS11990 homoserine O-succinyltransferase low > 34
Bacteroides stercoris CC31F 0.43 HMPREF1181_RS14140 3-isopropylmalate dehydratase small subunit 0.48 HMPREF1181_RS00105 homoserine O-succinyltransferase low > 56
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS10205 3-isopropylmalate dehydratase small subunit 0.48 ABI39_RS10360 homoserine O-succinyltransferase low > 72
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit 0.49 HMPREF1058_RS14680 homoserine O-succinyltransferase low > 67
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit 0.48 HMPREF1078_RS10000 homoserine O-succinyltransferase low > 61
Bacteroides ovatus ATCC 8483 0.39 BACOVA_04602 3-isopropylmalate dehydratase, small subunit 0.50 BACOVA_03007 homoserine O-succinyltransferase low > 94
Bacteroides thetaiotaomicron VPI-5482 0.39 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) 0.50 BT2413 homoserine O-succinyltransferase (NCBI ptt file) low > 81
Synechococcus elongatus PCC 7942 0.27 Synpcc7942_2548 leuD isopropylmalate isomerase small subunit 0.43 Synpcc7942_0371 metA homoserine O-succinyltransferase — —

Not shown: 53 genomes with orthologs for BWI76_RS04665 only; 0 genomes with orthologs for BWI76_RS01655 only