Conservation of cofitness between BWI76_RS21480 and BWI76_RS01615 in Klebsiella michiganensis M5al

48 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS21480 phospho-2-dehydro-3-deoxyheptonate aldolase 1.0 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.71 4
Enterobacter asburiae PDN3 0.94 EX28DRAFT_2702 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (EC 2.5.1.54) 0.96 EX28DRAFT_4545 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) — —
Enterobacter sp. TBS_079 0.93 MPMX20_03469 Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 0.96 MPMX20_00226 Bifunctional purine biosynthesis protein PurH 0.73 25
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_01107 Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 0.94 OHPLBJKB_04043 Bifunctional purine biosynthesis protein PurH low > 73
Escherichia coli BL21 0.92 ECD_02490 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible 0.94 ECD_03883 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase low > 61
Escherichia coli Nissle 1917 0.92 ECOLIN_RS14705 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 ECOLIN_RS23100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.50 41
Escherichia coli ECOR38 0.92 HEPCGN_20335 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 HEPCGN_11950 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 87
Escherichia coli ECRC62 0.92 BNILDI_11695 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 BNILDI_06065 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Escherichia coli ECRC100 0.92 OKFHMN_21215 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 OKFHMN_13310 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 80
Escherichia coli ECOR27 0.92 NOLOHH_12890 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 NOLOHH_05455 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Escherichia coli ECRC102 0.92 NIAGMN_18985 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 NIAGMN_11060 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECRC99 0.92 KEDOAH_07005 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 KEDOAH_14850 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECRC101 0.92 MCAODC_11745 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 MCAODC_03810 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.63 62
Escherichia coli BW25113 0.92 b2601 aroF 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible (NCBI) 0.94 b4006 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) 0.74 48
Escherichia coli ECRC98 0.92 JDDGAC_24880 aroF 3-deoxy-7-phosphoheptulonate synthase AroF 0.94 JDDGAC_16935 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF4176 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) 0.97 GFF4186 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 78
Escherichia fergusonii Becca 0.92 EFB2_01291 Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 0.94 EFB2_04604 Bifunctional purine biosynthesis protein PurH low > 86
Pantoea sp. MT58 0.85 IAI47_04400 3-deoxy-7-phosphoheptulonate synthase 0.90 IAI47_18040 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 76
Erwinia tracheiphila SCR3 0.82 LU632_RS15450 3-deoxy-7-phosphoheptulonate synthase 0.89 LU632_RS01020 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 74
Serratia liquefaciens MT49 0.81 IAI46_03955 3-deoxy-7-phosphoheptulonate synthase 0.89 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 86
Rahnella sp. WP5 0.81 EX31_RS07595 3-deoxy-7-phosphoheptulonate synthase 0.88 EX31_RS16860 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 89
Dickeya dianthicola ME23 0.80 DZA65_RS17355 3-deoxy-7-phosphoheptulonate synthase 0.90 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Dickeya dianthicola 67-19 0.80 HGI48_RS16260 3-deoxy-7-phosphoheptulonate synthase 0.90 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Dickeya dadantii 3937 0.80 DDA3937_RS16140 3-deoxy-7-phosphoheptulonate synthase 0.91 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pectobacterium carotovorum WPP14 0.80 HER17_RS05375 3-deoxy-7-phosphoheptulonate synthase 0.90 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Vibrio cholerae E7946 ATCC 55056 0.71 CSW01_03635 3-deoxy-7-phosphoheptulonate synthase 0.80 CSW01_01420 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase low > 62
Shewanella loihica PV-4 0.65 Shew_1067 phospho-2-dehydro-3-deoxyheptonate aldolase (RefSeq) 0.77 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 60
Shewanella sp. ANA-3 0.64 Shewana3_3013 phospho-2-dehydro-3-deoxyheptonate aldolase (RefSeq) 0.74 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.63 SO1361 aroF phospho-2-dehydro-3-deoxyheptonate aldolase, tyr-sensitive (NCBI ptt file) 0.73 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) 0.72 42
Shewanella amazonensis SB2B 0.63 Sama_0893 phospho-2-dehydro-3-deoxyheptonate aldolase (RefSeq) 0.76 Sama_0395 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.62 MIT1002_01314 Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 0.75 MIT1002_03959 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas stutzeri RCH2 0.60 Psest_2331 phospho-2-dehydro-3-deoxyheptonate aldolase 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. S08-1 0.58 OH686_01760 3-deoxy-7-phosphoheptulonate synthase 0.69 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas simiae WCS417 0.58 PS417_08430 phospho-2-dehydro-3-deoxyheptonate aldolase 0.68 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens SBW25 0.58 PFLU_RS08380 3-deoxy-7-phosphoheptulonate synthase 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH low > 109
Pseudomonas fluorescens SBW25-INTG 0.58 PFLU_RS08380 3-deoxy-7-phosphoheptulonate synthase 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas syringae pv. syringae B728a 0.58 Psyr_2073 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.58 Psyr_2073 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas putida KT2440 0.58 PP_2324 tyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase 0.68 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas fluorescens FW300-N1B4 0.58 Pf1N1B4_289 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) 0.68 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 87
Pseudomonas sp. RS175 0.58 PFR28_00962 Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 0.68 PFR28_05214 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas fluorescens FW300-N2E2 0.58 Pf6N2E2_2470 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) 0.68 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas fluorescens FW300-N2C3 0.58 AO356_03200 phospho-2-dehydro-3-deoxyheptonate aldolase 0.68 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.58 AO353_19030 phospho-2-dehydro-3-deoxyheptonate aldolase 0.68 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Marinobacter adhaerens HP15 0.58 HP15_1814 phospho-2-dehydro-3-heoxyheptonate aldolase 0.71 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas fluorescens GW456-L13 0.58 PfGW456L13_2224 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) 0.68 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Dechlorosoma suillum PS 0.53 Dsui_2381 phospho-2-dehydro-3-deoxyheptonate aldolase 0.54 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Acinetobacter radioresistens SK82 0.53 MPMX26_01673 Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 0.70 MPMX26_01141 Bifunctional purine biosynthesis protein PurH low > 36
Kangiella aquimarina DSM 16071 0.53 B158DRAFT_1384 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (EC 2.5.1.54) 0.70 B158DRAFT_0166 IMP cyclohydrolase (EC 3.5.4.10)/phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —

Not shown: 0 genomes with orthologs for BWI76_RS21480 only; 51 genomes with orthologs for BWI76_RS01615 only