Conservation of cofitness between BNILDI_14450 and BNILDI_06855 in Escherichia coli ECRC62

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC62 1.0 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC 1.0 BNILDI_06855 sugE quaternary ammonium compound efflux SMR transporter SugE 0.70 9
Escherichia coli ECOR27 1.00 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NOLOHH_04635 sugE quaternary ammonium compound efflux SMR transporter SugE low > 75
Escherichia coli BL21 1.00 ECD_01981 multidrug efflux system, subunit C 0.99 ECD_04020 multidrug efflux system protein low > 61
Escherichia coli ECRC98 1.00 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 JDDGAC_16010 sugE quaternary ammonium compound efflux SMR transporter SugE low > 86
Escherichia coli ECRC100 1.00 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 OKFHMN_12375 sugE quaternary ammonium compound efflux SMR transporter SugE low > 80
Escherichia coli ECRC101 1.00 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 MCAODC_02885 sugE quaternary ammonium compound efflux SMR transporter SugE low > 87
Escherichia coli ECRC102 1.00 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NIAGMN_10220 sugE quaternary ammonium compound efflux SMR transporter SugE — —
Escherichia coli ECRC99 1.00 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 KEDOAH_15790 sugE quaternary ammonium compound efflux SMR transporter SugE — —
Escherichia coli BW25113 1.00 b2076 mdtC multidrug efflux system, subunit C (NCBI) 1.00 b4148 sugE suppresses groEL, may be chaperone (VIMSS) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01628 Multidrug resistance protein MdtC 1.00 OHPLBJKB_03892 Quaternary ammonium compound-resistance protein SugE low > 73
Escherichia coli ECOR38 0.99 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 HEPCGN_10600 sugE quaternary ammonium compound efflux SMR transporter SugE low > 87
Escherichia coli Nissle 1917 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC 0.99 ECOLIN_RS24100 quaternary ammonium compound efflux SMR transporter SugE — —
Escherichia fergusonii Becca 0.99 EFB2_01779 Multidrug resistance protein MdtC 1.00 EFB2_04385 Guanidinium exporter low > 86
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump 0.89 EX28DRAFT_3348 Membrane transporters of cations and cationic drugs low > 76
Enterobacter sp. TBS_079 0.91 MPMX20_03062 Multidrug resistance protein MdtC 0.89 MPMX20_00430 Guanidinium exporter low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3853 Multidrug transporter MdtC 0.90 GFF2001 Quaternary ammonium compound-resistance protein SugE low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19260 multidrug transporter subunit MdtC 0.90 BWI76_RS02430 multidrug transporter low > 92
Serratia liquefaciens MT49 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC 0.82 IAI46_01525 quaternary ammonium compound efflux SMR transporter SugE low > 86
Pectobacterium carotovorum WPP14 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC 0.58 HER17_RS09145 multidrug efflux SMR transporter low > 75
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS19020 multidrug efflux RND transporter permease subunit 0.49 ABZR87_RS21585 multidrug efflux SMR transporter low > 80
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_22900 acriflavine resistance protein B 0.67 AO353_02525 molecular chaperone low > 101
Pseudomonas sp. S08-1 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) 0.74 OH686_19635 small multidrug resistance family (SMR) protein low > 80
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_3265 Acriflavin resistance plasma membrane protein 0.66 PfGW456L13_4218 Quaternary ammonium compound-resistance protein SugE low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_2484 Acriflavin resistance protein 0.26 Psyr_0541 Small multidrug resistance protein low > 86
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_2484 Acriflavin resistance protein 0.26 Psyr_0541 Small multidrug resistance protein low > 86
Pseudomonas fluorescens SBW25 0.53 PFLU_RS13435 MMPL family transporter 0.67 PFLU_RS09245 quaternary ammonium compound efflux SMR transporter SugE low > 109
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS13435 MMPL family transporter 0.67 PFLU_RS09245 quaternary ammonium compound efflux SMR transporter SugE low > 109
Pseudomonas stutzeri RCH2 0.53 Psest_2140 Cation/multidrug efflux pump 0.52 Psest_0857 Membrane transporters of cations and cationic drugs low > 67
Rahnella sp. WP5 0.53 EX31_RS13375 MMPL family transporter 0.60 EX31_RS00585 multidrug efflux SMR transporter low > 89
Pseudomonas simiae WCS417 0.53 PS417_12750 acriflavine resistance protein B 0.67 PS417_09235 molecular chaperone low > 88
Pseudomonas putida KT2440 0.53 PP_3583 multidrug efflux transport system - membrane subunit 0.67 PP_1701 transporter — —
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_1271 Acriflavin resistance plasma membrane protein 0.66 Pf6N2E2_5766 Quaternary ammonium compound-resistance protein SugE low > 103
Pseudomonas fluorescens FW300-N2C3 0.52 AO356_25880 acriflavine resistance protein B 0.66 AO356_19255 molecular chaperone low > 104
Pseudomonas sp. RS175 0.51 PFR28_02193 Multidrug resistance protein MdtC 0.66 PFR28_03184 Guanidinium exporter low > 88
Rhodopseudomonas palustris CGA009 0.49 TX73_018025 multidrug efflux RND transporter permease subunit 0.63 TX73_011815 quaternary ammonium compound efflux SMR transporter SugE low > 86
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS29845 efflux RND transporter permease subunit 0.62 QEN71_RS24335 quaternary ammonium compound efflux SMR transporter SugE low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF488 RND multidrug efflux transporter; Acriflavin resistance protein 0.32 GFF4245 Ethidium bromide-methyl viologen resistance protein EmrE low > 90
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_06491 multidrug efflux pump 0.63 H281DRAFT_04535 quaternary ammonium compound-resistance protein SugE low > 103
Azospirillum brasilense Sp245 0.44 AZOBR_RS14670 multidrug transporter 0.65 AZOBR_RS09160 multidrug transporter low > 97
Desulfovibrio vulgaris Hildenborough JW710 0.43 DVU0438 AcrB/AcrD/AcrF family protein (TIGR) 0.34 DVU1996 quaternary ammonium compound-resistance protein QacC, putative (TIGR) 0.28 46
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS07780 nodulation protein 0.63 BPHYT_RS06470 membrane protein low > 109
Desulfovibrio vulgaris Miyazaki F 0.43 DvMF_1515 acriflavin resistance protein (RefSeq) 0.63 DvMF_3195 small multidrug resistance protein (RefSeq) low > 51
Bosea sp. OAE506 0.41 ABIE41_RS20140 efflux RND transporter permease subunit 0.68 ABIE41_RS19675 quaternary ammonium compound efflux SMR transporter SugE low > 77
Variovorax sp. OAS795 0.39 ABID97_RS06490 efflux RND transporter permease subunit 0.66 ABID97_RS10520 quaternary ammonium compound efflux SMR transporter SugE low > 91
Rhizobium sp. OAE497 0.39 ABIE40_RS05760 efflux RND transporter permease subunit 0.61 ABIE40_RS09885 quaternary ammonium compound efflux SMR transporter SugE low > 107
Pontibacter actiniarum KMM 6156, DSM 19842 0.24 CA264_13040 acriflavin resistance protein 0.57 CA264_20035 QacE family quaternary ammonium compound efflux SMR transporter — —
Acinetobacter radioresistens SK82 0.24 MPMX26_02516 Multidrug resistance protein MdtC 0.54 MPMX26_02568 Guanidinium exporter low > 36
Sinorhizobium meliloti 1021 0.23 SMc01457 transport transmembrane protein 0.63 SMc01278 chaperone-like protein low > 103
Caulobacter crescentus NA1000 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.65 CCNA_03556 multidrug efflux system protein low > 66
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.65 CCNA_03556 multidrug efflux system protein low > 67

Not shown: 14 genomes with orthologs for BNILDI_14450 only; 23 genomes with orthologs for BNILDI_06855 only