Conservation of cofitness between Atu0040 and Atu2718 in Agrobacterium fabrum C58

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu0040 phosphoribosylformino-5-aminoimidazole carboxamide ribotide isomerase 1.0 Atu2718 homoserine O-succinyltransferase 0.70 15
Rhizobium sp. OAE497 0.92 ABIE40_RS19445 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.86 ABIE40_RS18590 homoserine O-succinyltransferase 0.92 33
Sinorhizobium meliloti 1021 0.91 SMc02570 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) 0.85 SMc03797 homoserine O-succinyltransferase 0.86 20
Azospirillum brasilense Sp245 0.61 AZOBR_RS01680 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) 0.60 AZOBR_RS14010 homoserine O-succinyltransferase low > 97
Dinoroseobacter shibae DFL-12 0.59 Dshi_2578 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (RefSeq) 0.62 Dshi_1593 Homoserine O-succinyltransferase (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.59 PGA1_c09270 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HisA 0.61 PGA1_c14560 homoserine O-succinyltransferase MetA — —
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS27840 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.54 QEN71_RS42530 homoserine O-succinyltransferase low > 153
Synechococcus elongatus PCC 7942 0.39 Synpcc7942_1829 hisA 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 0.44 Synpcc7942_0371 metA homoserine O-succinyltransferase — —
Parabacteroides merdae CL09T00C40 0.31 HMPREF1078_RS13570 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.49 HMPREF1078_RS10000 homoserine O-succinyltransferase low > 61
Phocaeicola vulgatus CL09T03C04 0.31 HMPREF1058_RS06170 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.47 HMPREF1058_RS14680 homoserine O-succinyltransferase low > 67
Phocaeicola dorei CL03T12C01 0.31 ABI39_RS19925 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.48 ABI39_RS10360 homoserine O-succinyltransferase low > 72
Klebsiella michiganensis M5al 0.29 BWI76_RS18945 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase 0.44 BWI76_RS01655 homoserine O-succinyltransferase — —
Rahnella sp. WP5 0.28 EX31_RS11460 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.44 EX31_RS11735 homoserine O-succinyltransferase 0.95 4
Shewanella amazonensis SB2B 0.28 Sama_1946 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (RefSeq) 0.45 Sama_1374 homoserine O-succinyltransferase (RefSeq) 0.97 8
Bacteroides stercoris CC31F 0.28 HMPREF1181_RS11075 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.48 HMPREF1181_RS00105 homoserine O-succinyltransferase low > 56
Dickeya dianthicola 67-19 0.28 HGI48_RS09725 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.43 HGI48_RS19155 homoserine O-succinyltransferase — —
Pectobacterium carotovorum WPP14 0.28 HER17_RS12250 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.44 HER17_RS02285 homoserine O-succinyltransferase 0.96 14
Serratia liquefaciens MT49 0.28 IAI46_08190 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.42 IAI46_23200 homoserine O-succinyltransferase low > 86
Dickeya dianthicola ME23 0.28 DZA65_RS10035 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.43 DZA65_RS20275 homoserine O-succinyltransferase — —
Erwinia tracheiphila SCR3 0.28 LU632_RS08925 hisA 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.43 LU632_RS22410 metA homoserine O-succinyltransferase low > 74
Shewanella sp. ANA-3 0.27 Shewana3_1849 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (RefSeq) 0.43 Shewana3_2772 homoserine O-succinyltransferase (RefSeq) 0.93 14
Enterobacter sp. TBS_079 0.27 MPMX20_03006 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 0.43 MPMX20_00230 Homoserine O-succinyltransferase 0.92 19
Alteromonas macleodii MIT1002 0.27 MIT1002_02637 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 0.44 MIT1002_01112 Homoserine O-succinyltransferase 0.95 34
Dickeya dadantii 3937 0.27 DDA3937_RS09715 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.43 DDA3937_RS19065 homoserine O-succinyltransferase 0.87 18
Enterobacter asburiae PDN3 0.27 EX28DRAFT_0535 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (EC 5.3.1.16) 0.42 EX28DRAFT_4331 homoserine O-succinyltransferase (EC 2.3.1.46) 0.89 16
Bacteroides thetaiotaomicron VPI-5482 0.26 BT1379 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) 0.50 BT2413 homoserine O-succinyltransferase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.26 BACOVA_00220 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.51 BACOVA_03007 homoserine O-succinyltransferase low > 94
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.26 GFF3908 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) 0.43 GFF1350 Homoserine O-succinyltransferase (EC 2.3.1.46) low > 78
Shewanella oneidensis MR-1 0.26 SO2069 hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (NCBI ptt file) 0.44 SO1676 metA homoserine O-succinyltransferase (NCBI ptt file) 0.96 22
Escherichia coli HS(pFamp)R (ATCC 700891) 0.26 OHPLBJKB_01676 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 0.44 OHPLBJKB_04037 Homoserine O-succinyltransferase low > 73
Escherichia coli BL21 0.26 ECD_01926 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase 0.44 ECD_03885 homoserine O-transsuccinylase low > 60
Escherichia coli ECOR27 0.26 NOLOHH_15810 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 NOLOHH_05420 metA homoserine O-succinyltransferase low > 57
Bifidobacterium breve UCC2003 0.26 BBR_RS17030 bifunctional 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase/phosphoribosylanthranilate isomerase PriA 0.39 BBR_RS11990 homoserine O-succinyltransferase low > 34
Vibrio cholerae E7946 ATCC 55056 0.26 CSW01_05770 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.43 CSW01_08100 homoserine O-succinyltransferase low > 62
Escherichia fergusonii Becca 0.26 EFB2_01832 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 0.44 EFB2_04597 Homoserine O-succinyltransferase low > 86
Escherichia coli ECRC62 0.26 BNILDI_14720 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 BNILDI_06100 metA homoserine O-succinyltransferase — —
Escherichia coli ECRC101 0.26 MCAODC_20445 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 MCAODC_03775 metA homoserine O-succinyltransferase — —
Escherichia coli ECRC98 0.26 JDDGAC_28605 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 JDDGAC_16900 metA homoserine O-succinyltransferase — —
Escherichia coli ECRC101 0.26 OKFHMN_24495 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 OKFHMN_13275 metA homoserine O-succinyltransferase — —
Escherichia coli ECRC99 0.26 KEDOAH_03655 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 KEDOAH_14885 metA homoserine O-succinyltransferase — —
Escherichia coli ECOR38 0.26 HEPCGN_03200 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 HEPCGN_11915 metA homoserine O-succinyltransferase low > 85
Escherichia coli ECRC102 0.26 NIAGMN_22440 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.44 NIAGMN_11025 metA homoserine O-succinyltransferase — —
Pantoea sp. MT58 0.25 IAI47_07070 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.43 IAI47_18015 homoserine O-succinyltransferase 0.96 19
Escherichia coli BW25113 0.25 b2024 hisA N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) 0.44 b4013 metA homoserine O-succinyltransferase (NCBI) 0.80 60
Escherichia coli Nissle 1917 0.25 ECOLIN_RS11965 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase 0.44 ECOLIN_RS25515 homoserine O-succinyltransferase — —
Shewanella loihica PV-4 0.24 Shew_2202 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (RefSeq) 0.44 Shew_2551 homoserine O-succinyltransferase (RefSeq) 0.86 36

Not shown: 56 genomes with orthologs for Atu0040 only; 0 genomes with orthologs for Atu2718 only