Conservation of cofitness between Shewana3_1847 and Shewana3_3612 in Shewanella sp. ANA-3

48 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Shewanella sp. ANA-3 1.0 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 1.0 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.95 2
Shewanella oneidensis MR-1 0.86 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 1.00 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.93 21
Shewanella loihica PV-4 0.73 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.93 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.96 12
Shewanella amazonensis SB2B 0.66 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.92 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.96 12
Enterobacter sp. TBS_079 0.57 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.75 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.75 63
Alteromonas macleodii MIT1002 0.56 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase 0.67 MIT1002_03670 5,10-methylenetetrahydrofolate reductase low > 70
Pantoea sp. MT58 0.56 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.74 IAI47_00890 methylenetetrahydrofolate reductase low > 76
Escherichia coli BL21 0.56 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase 0.75 ECD_03827 5,10-methylenetetrahydrofolate reductase low > 60
Escherichia coli BW25113 0.56 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.75 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.95 8
Escherichia coli ECOR38 0.56 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 HEPCGN_12310 metF methylenetetrahydrofolate reductase low > 85
Klebsiella michiganensis M5al 0.55 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.76 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 0.85 32
Enterobacter asburiae PDN3 0.55 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.75 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form low > 76
Dickeya dianthicola 67-19 0.55 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 HGI48_RS20415 methylenetetrahydrofolate reductase low > 71
Dickeya dadantii 3937 0.55 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.76 DDA3937_RS00960 methylenetetrahydrofolate reductase low > 74
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.73 CSW01_13560 methylenetetrahydrofolate reductase low > 62
Dickeya dianthicola ME23 0.55 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.74 DZA65_RS21460 methylenetetrahydrofolate reductase 0.70 49
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE 0.75 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase low > 73
Escherichia coli ECRC62 0.54 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 BNILDI_05725 metF methylenetetrahydrofolate reductase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.52 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.76 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 78
Escherichia coli Nissle 1917 0.51 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 ECOLIN_RS22760 methylenetetrahydrofolate reductase
Escherichia fergusonii Becca 0.51 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE 0.75 EFB2_04672 5,10-methylenetetrahydrofolate reductase low > 86
Escherichia coli ECRC102 0.51 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 NIAGMN_11420 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC99 0.51 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 KEDOAH_14495 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC101 0.51 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 OKFHMN_13665 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC98 0.51 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 JDDGAC_17290 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC101 0.51 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 MCAODC_04165 metF methylenetetrahydrofolate reductase
Rahnella sp. WP5 0.51 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 EX31_RS14205 methylenetetrahydrofolate reductase 0.88 62
Escherichia coli ECOR27 0.51 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 NOLOHH_05810 metF methylenetetrahydrofolate reductase low > 57
Serratia liquefaciens MT49 0.50 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 IAI46_24530 methylenetetrahydrofolate reductase low > 86
Erwinia tracheiphila SCR3 0.49 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.74 LU632_RS19630 metF methylenetetrahydrofolate reductase low > 74
Rhodanobacter denitrificans MT42 0.49 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.34 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] 0.52 58
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.34 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H] low > 52
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.35 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H] 0.93 26
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.34 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H] 0.71 30
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.34 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 74
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS13560 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.18 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] low > 61
Pectobacterium carotovorum WPP14 0.47 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.74 HER17_RS00950 methylenetetrahydrofolate reductase low > 75
Bacteroides ovatus ATCC 8483 0.47 BACOVA_00218 phosphoribosyl-ATP diphosphatase 0.16 BACOVA_03666 methylenetetrahydrofolate reductase (NAD(P)H) low > 94
Lysobacter sp. OAE881 0.47 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.33 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] 0.95 26
Bacteroides thetaiotaomicron VPI-5482 0.47 BT1377 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) 0.19 BT3821 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) low > 81
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS11065 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.17 HMPREF1181_RS00120 methylenetetrahydrofolate reductase [NAD(P)H] low > 56
Phocaeicola vulgatus CL09T03C04 0.45 HMPREF1058_RS06180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.17 HMPREF1058_RS13650 methylenetetrahydrofolate reductase [NAD(P)H] low > 67
Phocaeicola dorei CL03T12C01 0.45 ABI39_RS19935 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.17 ABI39_RS09240 methylenetetrahydrofolate reductase [NAD(P)H] low > 72
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2517 phosphoribosyl-ATP pyrophosphohydrolase 0.19 Echvi_3637 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.85 31
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS03605 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.20 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H] 0.94 10
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.19 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H]
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.20 CA264_16780 methylenetetrahydrofolate reductase [NAD(P)H] low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.46 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H] 0.99 25
Acinetobacter radioresistens SK82 0.27 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE 0.31 MPMX26_01002 5,10-methylenetetrahydrofolate reductase low > 36

Not shown: 1 genomes with orthologs for Shewana3_1847 only; 51 genomes with orthologs for Shewana3_3612 only