Conservation of cofitness between BT3361 and BT1381 in Bacteroides thetaiotaomicron VPI-5482

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT3361 erythronate-4-phosphate dehydrogenase (NCBI ptt file) 1.0 BT1381 formyltetrahydrofolate deformylase (NCBI ptt file) 0.87 8
Bacteroides ovatus ATCC 8483 0.84 BACOVA_01953 4-phosphoerythronate dehydrogenase 0.99 BACOVA_00222 formyltetrahydrofolate deformylase 0.83 3
Bacteroides stercoris CC31F 0.76 HMPREF1181_RS02440 4-phosphoerythronate dehydrogenase PdxB 0.89 HMPREF1181_RS11085 formyltetrahydrofolate deformylase — —
Phocaeicola vulgatus CL09T03C04 0.62 HMPREF1058_RS10820 4-phosphoerythronate dehydrogenase PdxB 0.92 HMPREF1058_RS06160 formyltetrahydrofolate deformylase 0.93 4
Phocaeicola dorei CL03T12C01 0.62 ABI39_RS06250 4-phosphoerythronate dehydrogenase PdxB 0.91 ABI39_RS19915 formyltetrahydrofolate deformylase 0.79 14
Rahnella sp. WP5 0.34 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.38 EX31_RS10115 formyltetrahydrofolate deformylase 0.76 56
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.34 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.38 GFF2756 Formyltetrahydrofolate deformylase (EC 3.5.1.10) low > 78
Pseudomonas syringae pv. syringae B728a 0.33 Psyr_1828 4-phosphoerythronate dehydrogenase 0.45 Psyr_4018 Formyltetrahydrofolate deformylase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.33 Psyr_1828 4-phosphoerythronate dehydrogenase 0.45 Psyr_4018 Formyltetrahydrofolate deformylase — —
Dickeya dadantii 3937 0.33 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB 0.38 DDA3937_RS10325 formyltetrahydrofolate deformylase 0.61 44
Dickeya dianthicola ME23 0.32 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB 0.38 DZA65_RS10810 formyltetrahydrofolate deformylase low > 75
Vibrio cholerae E7946 ATCC 55056 0.32 CSW01_10525 DUF3410 domain-containing protein 0.38 CSW01_09940 formyltetrahydrofolate deformylase — —
Escherichia coli Nissle 1917 0.32 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.38 ECOLIN_RS07460 formyltetrahydrofolate deformylase low > 52
Escherichia coli BL21 0.32 ECD_02245 erythronate-4-phosphate dehydrogenase 0.38 ECD_01208 formyltetrahydrofolate hydrolase low > 60
Escherichia fergusonii Becca 0.32 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.38 EFB2_02694 Formyltetrahydrofolate deformylase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.32 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.38 OHPLBJKB_02453 Formyltetrahydrofolate deformylase low > 73
Escherichia coli ECRC101 0.32 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 OKFHMN_28570 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC99 0.32 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 KEDOAH_25565 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC101 0.32 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 MCAODC_21690 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC102 0.32 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 NIAGMN_27665 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC98 0.32 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 JDDGAC_06005 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECRC62 0.31 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 BNILDI_18635 purU formyltetrahydrofolate deformylase — —
Escherichia coli ECOR38 0.31 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 HEPCGN_25030 purU formyltetrahydrofolate deformylase low > 85
Escherichia coli ECOR27 0.31 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.38 NOLOHH_20480 purU formyltetrahydrofolate deformylase low > 57
Enterobacter asburiae PDN3 0.31 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.38 EX28DRAFT_0858 formyltetrahydrofolate deformylase low > 76
Escherichia coli BW25113 0.31 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.38 b1232 purU formyltetrahydrofolate deformylase (NCBI) low > 76
Klebsiella michiganensis M5al 0.31 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 0.38 BWI76_RS17290 formyltetrahydrofolate deformylase low > 92
Pseudomonas fluorescens FW300-N1B4 0.31 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.46 Pf1N1B4_665 Formyltetrahydrofolate deformylase (EC 3.5.1.10) — —
Pseudomonas fluorescens GW456-L13 0.31 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.45 PfGW456L13_1825 Formyltetrahydrofolate deformylase (EC 3.5.1.10) — —
Enterobacter sp. TBS_079 0.31 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.38 MPMX20_02596 Formyltetrahydrofolate deformylase 0.30 84
Serratia liquefaciens MT49 0.30 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.38 IAI46_14265 formyltetrahydrofolate deformylase low > 86
Pseudomonas fluorescens FW300-N2E3 0.30 AO353_00545 erythronate-4-phosphate dehydrogenase 0.45 AO353_03710 formyltetrahydrofolate deformylase — —
Erwinia tracheiphila SCR3 0.30 LU632_RS07815 DUF3410 domain-containing protein 0.37 LU632_RS12940 purU formyltetrahydrofolate deformylase — —
Shewanella oneidensis MR-1 0.30 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.36 SO1624 purU formyltetrahydrofolate deformylase (NCBI ptt file) — —
Shewanella sp. ANA-3 0.30 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.36 Shewana3_2821 purU formyltetrahydrofolate deformylase (RefSeq) — —
Pseudomonas simiae WCS417 0.30 PS417_07535 erythronate-4-phosphate dehydrogenase 0.45 PS417_22565 formyltetrahydrofolate deformylase — —
Acinetobacter radioresistens SK82 0.29 MPMX26_02238 Erythronate-4-phosphate dehydrogenase 0.44 MPMX26_00378 Formyltetrahydrofolate deformylase low > 36
Pectobacterium carotovorum WPP14 0.29 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB 0.39 HER17_RS11065 formyltetrahydrofolate deformylase 0.61 28
Pseudomonas fluorescens FW300-N2E2 0.29 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.45 Pf6N2E2_5508 Formyltetrahydrofolate deformylase (EC 3.5.1.10) — —
Pseudomonas putida KT2440 0.29 PP_2117 Erythronate-4-phosphate dehydrogenase 0.44 PP_1367 formyltetrahydrofolate hydrolase — —
Pseudomonas fluorescens FW300-N2C3 0.29 AO356_02365 erythronate-4-phosphate dehydrogenase 0.44 AO356_17895 formyltetrahydrofolate deformylase — —
Pseudomonas fluorescens SBW25 0.29 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.45 PFLU_RS24200 formyltetrahydrofolate deformylase — —
Pseudomonas fluorescens SBW25-INTG 0.29 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.45 PFLU_RS24200 formyltetrahydrofolate deformylase — —
Pantoea sp. MT58 0.29 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.38 IAI47_09010 formyltetrahydrofolate deformylase 0.76 25
Pseudomonas stutzeri RCH2 0.29 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.46 Psest_3178 formyltetrahydrofolate deformylase — —
Pseudomonas sp. RS175 0.29 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.45 PFR28_03439 Formyltetrahydrofolate deformylase — —
Shewanella loihica PV-4 0.28 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.36 Shew_2640 purU formyltetrahydrofolate deformylase (RefSeq) — —
Dickeya dianthicola 67-19 0.28 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB 0.38 HGI48_RS10335 formyltetrahydrofolate deformylase low > 71
Pseudomonas sp. S08-1 0.27 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.45 OH686_18295 formyltetrahydrofolate deformylase — —
Alteromonas macleodii MIT1002 0.27 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.40 MIT1002_00404 Formyltetrahydrofolate deformylase — —
Shewanella amazonensis SB2B 0.26 Sama_2153 erythronate-4-phosphate dehydrogenase (RefSeq) 0.35 Sama_1134 purU formyltetrahydrofolate deformylase (RefSeq) — —

Not shown: 3 genomes with orthologs for BT3361 only; 39 genomes with orthologs for BT1381 only