Conservation of cofitness between b2022 and b3771 in Escherichia coli BW25113

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 1.0 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.98 1
Escherichia coli ECRC101 1.00 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECOR27 1.00 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Escherichia coli ECRC98 1.00 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC102 1.00 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 1.00 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 1.00 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECOR38 0.99 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Escherichia coli BL21 0.99 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase 1.00 ECD_03649 dihydroxyacid dehydratase low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB 1.00 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia fergusonii Becca 0.99 EFB2_01834 Histidine biosynthesis bifunctional protein HisB 0.99 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Escherichia coli ECRC62 0.99 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.99 ECOLIN_RS21665 dihydroxy-acid dehydratase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.97 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Enterobacter sp. TBS_079 0.92 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.97 MPMX20_04499 Dihydroxy-acid dehydratase 0.96 6
Enterobacter asburiae PDN3 0.91 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.96 EX28DRAFT_4443 dihydroxy-acid dehydratase 0.91 12
Klebsiella michiganensis M5al 0.88 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.96 BWI76_RS00975 dihydroxy-acid dehydratase 0.91 4
Dickeya dadantii 3937 0.84 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 DDA3937_RS20155 dihydroxy-acid dehydratase 0.89 25
Dickeya dianthicola 67-19 0.84 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 HGI48_RS20295 dihydroxy-acid dehydratase 0.72 20
Dickeya dianthicola ME23 0.84 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 DZA65_RS21335 dihydroxy-acid dehydratase 0.75 32
Serratia liquefaciens MT49 0.84 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 IAI46_24345 dihydroxy-acid dehydratase 0.55 80
Pectobacterium carotovorum WPP14 0.83 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 HER17_RS01075 dihydroxy-acid dehydratase 0.98 1
Rahnella sp. WP5 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.87 EX31_RS15005 dihydroxy-acid dehydratase 0.95 13
Erwinia tracheiphila SCR3 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.86 LU632_RS24400 ilvD dihydroxy-acid dehydratase low > 74
Pantoea sp. MT58 0.82 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.89 IAI47_01035 dihydroxy-acid dehydratase 0.98 5
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase 0.85 CSW01_00140 dihydroxy-acid dehydratase low > 62
Shewanella loihica PV-4 0.66 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.78 Shew_0292 dihydroxy-acid dehydratase (RefSeq) 0.98 18
Alteromonas macleodii MIT1002 0.65 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.79 MIT1002_04041 Dihydroxy-acid dehydratase 0.96 26
Shewanella amazonensis SB2B 0.64 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.79 Sama_3279 dihydroxy-acid dehydratase (RefSeq) 0.96 6
Shewanella oneidensis MR-1 0.63 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.80 SO4345 ilvD dihydroxy-acid dehydratase (NCBI ptt file) 0.98 3
Shewanella sp. ANA-3 0.63 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.80 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) 0.99 1
Lysobacter sp. OAE881 0.54 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase 0.86 10
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.28 ABZR86_RS15945 dihydroxy-acid dehydratase 0.91 40
Rhodanobacter denitrificans MT42 0.53 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.26 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.26 LRK54_RS10320 dihydroxy-acid dehydratase 0.57 29
Xanthomonas campestris pv. campestris strain 8004 0.53 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.72 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.70 52
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.27 OKGIIK_13600 ilvD dihydroxy-acid dehydratase low > 52
Pontibacter actiniarum KMM 6156, DSM 19842 0.47 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.28 CA264_06935 dihydroxy-acid dehydratase low > 74
Bacteroides thetaiotaomicron VPI-5482 0.46 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.63 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) 0.88 17
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.64 HMPREF1181_RS08335 dihydroxy-acid dehydratase 0.83 40
Bacteroides ovatus ATCC 8483 0.46 BACOVA_01232 histidinol-phosphatase 0.62 BACOVA_03302 dihydroxy-acid dehydratase 0.94 23
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.65 HMPREF1078_RS16695 dihydroxy-acid dehydratase low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2457 histidinol-phosphatase 0.29 Echvi_2055 dihydroxy-acid dehydratase 0.90 11
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.64 HMPREF1058_RS16815 dihydroxy-acid dehydratase 0.84 28
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.64 ABI39_RS12715 dihydroxy-acid dehydratase 0.86 9
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase 0.81 2
Pedobacter sp. GW460-11-11-14-LB5 0.42 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.27 CA265_RS15795 dihydroxy-acid dehydratase 0.92 20

Not shown: 0 genomes with orthologs for b2022 only; 55 genomes with orthologs for b3771 only