Conservation of cofitness between b2022 and b3770 in Escherichia coli BW25113

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.98 3
Escherichia coli ECRC101 1.00 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC99 1.00 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 1.00 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC98 1.00 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC102 1.00 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECOR27 1.00 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase low > 57
Escherichia coli BL21 0.99 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase 1.00 ECD_03648 branched-chain amino acid aminotransferase 0.66 3
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia coli ECOR38 0.99 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia fergusonii Becca 0.99 EFB2_01834 Histidine biosynthesis bifunctional protein HisB 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Escherichia coli ECRC62 0.99 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.98 GFF2902 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 78
Enterobacter sp. TBS_079 0.92 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Enterobacter asburiae PDN3 0.91 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I 0.91 13
Klebsiella michiganensis M5al 0.88 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.97 BWI76_RS00970 branched chain amino acid aminotransferase 0.54 85
Dickeya dadantii 3937 0.84 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.81 47
Dickeya dianthicola 67-19 0.84 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase low > 71
Dickeya dianthicola ME23 0.84 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 DZA65_RS21340 branched-chain amino acid transaminase 0.66 56
Serratia liquefaciens MT49 0.84 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Pectobacterium carotovorum WPP14 0.83 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 HER17_RS01070 branched-chain amino acid transaminase low > 75
Rahnella sp. WP5 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 EX31_RS15000 branched-chain amino acid transaminase 0.94 36
Erwinia tracheiphila SCR3 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 LU632_RS24405 branched-chain amino acid transaminase 0.74 37
Pantoea sp. MT58 0.82 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 IAI47_01030 branched-chain amino acid transaminase 0.98 13
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase 0.75 CSW01_00145 branched-chain-amino-acid transaminase low > 62
Shewanella loihica PV-4 0.66 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.68 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) 0.94 33
Alteromonas macleodii MIT1002 0.65 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 0.94 45
Shewanella amazonensis SB2B 0.64 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.19 Sama_3299 branched-chain amino acid aminotransferase (RefSeq) low > 62
Shewanella oneidensis MR-1 0.63 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.19 SO0340 ilvE branched-chain amino acid aminotransferase (NCBI ptt file) 0.85 74
Shewanella sp. ANA-3 0.63 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.19 Shewana3_3830 branched-chain amino acid aminotransferase (RefSeq) low > 73
Lysobacter sp. OAE881 0.54 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.94 4
Rhodanobacter denitrificans MT42 0.53 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.56 LRK55_RS11755 branched-chain amino acid transaminase low > 63
Xanthomonas campestris pv. campestris strain 8004 0.53 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.19 Xcc-8004.4199.1 Branched-chain amino acid aminotransferase (EC 2.6.1.42) 0.69 56
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.56 OKGIIK_11840 ilvE branched-chain amino acid transaminase low > 52
Pontibacter actiniarum KMM 6156, DSM 19842 0.47 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.32 CA264_06940 branched-chain amino acid aminotransferase low > 74
Bacteroides thetaiotaomicron VPI-5482 0.46 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.19 BT3892 branched-chain amino acid aminotransferase (NCBI ptt file) — —
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.19 HMPREF1181_RS06865 branched-chain amino acid aminotransferase low > 56
Bacteroides ovatus ATCC 8483 0.46 BACOVA_01232 histidinol-phosphatase 0.30 BACOVA_03679 branched-chain-amino-acid transaminase low > 94
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.19 HMPREF1078_RS07855 branched-chain amino acid aminotransferase low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2457 histidinol-phosphatase 0.18 Echvi_2202 branched-chain amino acid aminotransferase, group II low > 79
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.18 HMPREF1058_RS02220 branched-chain amino acid aminotransferase low > 67
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.18 ABI39_RS01415 branched-chain amino acid aminotransferase 0.75 46
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.16 ABZR88_RS22095 branched-chain amino acid aminotransferase — —
Pedobacter sp. GW460-11-11-14-LB5 0.42 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.29 CA265_RS15785 branched-chain-amino-acid transaminase low > 88

Not shown: 0 genomes with orthologs for b2022 only; 56 genomes with orthologs for b3770 only