Conservation of cofitness between b3500 and b2688 in Escherichia coli BW25113

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3500 gor glutathione reductase (NCBI) 1.0 b2688 gshA glutamate--cysteine ligase (NCBI) 0.30 9
Escherichia coli ECOR27 1.00 NOLOHH_08340 gorA glutathione-disulfide reductase 0.99 NOLOHH_12600 gshA glutamate--cysteine ligase 0.89 43
Escherichia coli ECRC62 1.00 BNILDI_03220 gorA glutathione-disulfide reductase 0.99 BNILDI_11160 gshA glutamate--cysteine ligase — —
Escherichia coli BL21 1.00 ECD_03349 glutathione oxidoreductase 1.00 ECD_02543 glutamate-cysteine ligase low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00203 Glutathione reductase 1.00 OHPLBJKB_01045 Glutamate--cysteine ligase 0.96 3
Escherichia coli ECOR38 1.00 HEPCGN_15315 gorA glutathione-disulfide reductase 1.00 HEPCGN_19955 gshA glutamate--cysteine ligase 0.93 44
Escherichia coli ECRC98 1.00 JDDGAC_20035 gorA glutathione-disulfide reductase 1.00 JDDGAC_24425 gshA glutamate--cysteine ligase — —
Escherichia coli ECRC99 1.00 KEDOAH_11740 gorA glutathione-disulfide reductase 1.00 KEDOAH_07375 gshA glutamate--cysteine ligase — —
Escherichia coli ECRC102 1.00 NIAGMN_14170 gorA glutathione-disulfide reductase 1.00 NIAGMN_18530 gshA glutamate--cysteine ligase — —
Escherichia coli ECRC101 1.00 MCAODC_06920 gorA glutathione-disulfide reductase 1.00 MCAODC_11285 gshA glutamate--cysteine ligase — —
Escherichia coli ECRC101 1.00 OKFHMN_16405 gorA glutathione-disulfide reductase 1.00 OKFHMN_20760 gshA glutamate--cysteine ligase — —
Escherichia fergusonii Becca 0.99 EFB2_00315 Glutathione reductase 1.00 EFB2_01238 Glutamate--cysteine ligase 0.83 1
Escherichia coli Nissle 1917 0.99 ECOLIN_RS19995 glutathione-disulfide reductase 1.00 ECOLIN_RS14990 glutamate--cysteine ligase 0.61 28
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF513 Glutathione reductase (EC 1.8.1.7) 0.95 GFF1597 Glutamate--cysteine ligase (EC 6.3.2.2) 0.87 5
Klebsiella michiganensis M5al 0.91 BWI76_RS26685 glutathione-disulfide reductase 0.88 BWI76_RS22120 glutamate--cysteine ligase 0.79 2
Enterobacter sp. TBS_079 0.90 MPMX20_04399 Glutathione reductase 0.88 MPMX20_03568 Glutamate--cysteine ligase 0.40 58
Enterobacter asburiae PDN3 0.90 EX28DRAFT_4061 NADPH-glutathione reductase (EC 1.8.1.7) 0.88 EX28DRAFT_2774 glutamate-cysteine ligase (EC 6.3.2.2) 0.83 3
Pantoea sp. MT58 0.87 IAI47_01325 glutathione-disulfide reductase 0.70 IAI47_04350 glutamate--cysteine ligase low > 76
Pectobacterium carotovorum WPP14 0.86 HER17_RS21240 glutathione-disulfide reductase 0.74 HER17_RS05095 glutamate--cysteine ligase low > 75
Dickeya dianthicola ME23 0.86 DZA65_RS00055 glutathione-disulfide reductase 0.72 DZA65_RS17400 glutamate--cysteine ligase low > 75
Dickeya dadantii 3937 0.85 DDA3937_RS21245 glutathione-disulfide reductase 0.74 DDA3937_RS16195 glutamate--cysteine ligase low > 74
Serratia liquefaciens MT49 0.85 IAI46_24240 glutathione-disulfide reductase 0.76 IAI46_03895 glutamate--cysteine ligase low > 86
Dickeya dianthicola 67-19 0.85 HGI48_RS00065 glutathione-disulfide reductase 0.72 HGI48_RS16305 glutamate--cysteine ligase low > 71
Rahnella sp. WP5 0.85 EX31_RS05175 glutathione-disulfide reductase 0.74 EX31_RS07750 glutamate--cysteine ligase low > 89
Erwinia tracheiphila SCR3 0.84 LU632_RS19495 gorA glutathione-disulfide reductase 0.70 LU632_RS15690 gshA glutamate--cysteine ligase low > 74
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_01000 glutathione-disulfide reductase 0.55 CSW01_02970 glutamate--cysteine ligase 0.65 53
Shewanella amazonensis SB2B 0.70 Sama_3543 glutathione reductase (RefSeq) 0.46 Sama_1058 glutamate--cysteine ligase (RefSeq) 0.43 13
Shewanella sp. ANA-3 0.70 Shewana3_4054 glutathione reductase (RefSeq) 0.43 Shewana3_3160 glutamate-cysteine ligase (RefSeq) — —
Shewanella oneidensis MR-1 0.70 SO4702 gor glutathione reductase (NCBI ptt file) 0.43 SO3559 gshA glutamate--cysteine ligase (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.70 Shew_3660 glutathione reductase (RefSeq) 0.43 Shew_1227 glutamate--cysteine ligase (RefSeq) 0.43 16
Alteromonas macleodii MIT1002 0.65 MIT1002_03638 Glutathione reductase 0.43 MIT1002_01222 Glutamate--cysteine ligase low > 70
Kangiella aquimarina DSM 16071 0.61 B158DRAFT_0460 NADPH-glutathione reductase (EC 1.8.1.7) 0.38 B158DRAFT_2251 glutamate-cysteine ligase (EC 6.3.2.2) — —
Pseudomonas putida KT2440 0.41 PP_3819 glutathione reductase (NADPH) 0.37 PP_0243 Glutamate--cysteine ligase — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS14555 glutathione-disulfide reductase 0.36 PFLU_RS01265 glutamate--cysteine ligase — —
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_2924 Glutathione reductase (EC 1.8.1.7) 0.37 PfGW456L13_430 Glutamate--cysteine ligase (EC 6.3.2.2) 0.46 10
Pseudomonas fluorescens FW300-N2E3 0.40 AO353_24480 glutathione reductase 0.37 AO353_11730 glutamate--cysteine ligase low > 101
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_22800 glutathione reductase 0.37 AO356_10185 glutamate--cysteine ligase 0.50 4
Pseudomonas fluorescens SBW25 0.40 PFLU_RS14555 glutathione-disulfide reductase 0.36 PFLU_RS01265 glutamate--cysteine ligase — —
Pseudomonas sp. S08-1 0.40 OH686_01610 glutathione-disulfide reductase 0.37 OH686_11110 glutamate--cysteine ligase low > 80
Pseudomonas simiae WCS417 0.40 PS417_14060 glutathione reductase 0.36 PS417_01155 glutamate--cysteine ligase — —
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_5014 Glutathione reductase (EC 1.8.1.7) 0.37 Pf1N1B4_1769 Glutamate--cysteine ligase (EC 6.3.2.2) — —
Pseudomonas fluorescens FW300-N2E2 0.39 Pf6N2E2_446 Glutathione reductase (EC 1.8.1.7) 0.37 Pf6N2E2_3908 Glutamate--cysteine ligase (EC 6.3.2.2) 0.35 33
Pseudomonas sp. RS175 0.39 PFR28_02483 Glutathione reductase 0.38 PFR28_04865 Glutamate--cysteine ligase low > 88
Pseudomonas stutzeri RCH2 0.38 Psest_2230 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes 0.36 Psest_3998 glutamate--cysteine ligase low > 67
Variovorax sp. SCN45 0.38 GFF3591 Glutathione reductase (EC 1.8.1.7) 0.32 GFF7064 Glutamate--cysteine ligase (EC 6.3.2.2) low > 127
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_2979 NADPH-glutathione reductase 0.35 Psyr_0255 glutamate-cysteine ligase — —
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_2979 NADPH-glutathione reductase 0.35 Psyr_0255 glutamate-cysteine ligase low > 86
Herbaspirillum seropedicae SmR1 0.37 HSERO_RS16580 glutathione reductase 0.35 HSERO_RS07300 glutamate--cysteine ligase low > 78
Variovorax sp. OAS795 0.36 ABID97_RS00865 glutathione-disulfide reductase 0.34 ABID97_RS20965 glutamate--cysteine ligase low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF372 Glutathione reductase (EC 1.8.1.7) 0.33 GFF3561 Glutamate--cysteine ligase (EC 6.3.2.2) low > 90
Marinobacter adhaerens HP15 0.34 HP15_1612 protein containing FAD-dependent pyridine nucleotide-disulfide oxidoreductase / Pyridine nucleotide-disulfide oxidoreductase, dimerization 0.33 HP15_217 glutamate--cysteine ligase — —

Not shown: 30 genomes with orthologs for b3500 only; 7 genomes with orthologs for b2688 only