| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 1.0 | b2022 | hisB | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | 0.97 | 4 |
| Escherichia coli ECRC62 | 1.00 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.99 | BNILDI_14730 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | 0.99 | OHPLBJKB_01678 | | Histidine biosynthesis bifunctional protein HisB | low | > 73 |
| Escherichia coli BL21 | 1.00 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.99 | ECD_01924 | | histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase | 0.49 | 50 |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 1.00 | NOLOHH_15820 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 57 |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.99 | HEPCGN_03210 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 85 |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 1.00 | JDDGAC_28615 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 1.00 | OKFHMN_24505 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 1.00 | NIAGMN_22450 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 1.00 | MCAODC_20435 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | 1.00 | KEDOAH_03645 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia fergusonii Becca | 0.99 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | 0.99 | EFB2_01834 | | Histidine biosynthesis bifunctional protein HisB | low | > 86 |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.99 | ECOLIN_RS11955 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.97 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.96 | GFF3910 | | Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) | low | > 78 |
| Enterobacter sp. TBS_079 | 0.95 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.92 | MPMX20_03004 | | Histidine biosynthesis bifunctional protein HisB | 0.75 | 13 |
| Klebsiella michiganensis M5al | 0.95 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 0.88 | BWI76_RS18935 | | bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase | 0.88 | 24 |
| Enterobacter asburiae PDN3 | 0.94 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.91 | EX28DRAFT_0537 | | imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) | low | > 76 |
| Pantoea sp. MT58 | 0.92 | IAI47_00890 | | methylenetetrahydrofolate reductase | 0.82 | IAI47_07080 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | 0.48 | 42 |
| Serratia liquefaciens MT49 | 0.91 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.84 | IAI46_08200 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 86 |
| Dickeya dadantii 3937 | 0.90 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | 0.84 | DDA3937_RS09725 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | 0.43 | 24 |
| Rahnella sp. WP5 | 0.89 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.83 | EX31_RS11450 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | 0.87 | 58 |
| Pectobacterium carotovorum WPP14 | 0.88 | HER17_RS00950 | | methylenetetrahydrofolate reductase | 0.83 | HER17_RS12240 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 75 |
| Dickeya dianthicola 67-19 | 0.88 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | 0.84 | HGI48_RS09735 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 71 |
| Dickeya dianthicola ME23 | 0.88 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.84 | DZA65_RS10045 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | 0.67 | 38 |
| Erwinia tracheiphila SCR3 | 0.86 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | 0.83 | LU632_RS08935 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 74 |
| Vibrio cholerae E7946 ATCC 55056 | 0.79 | CSW01_13560 | | methylenetetrahydrofolate reductase | 0.68 | CSW01_05760 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase | low | > 62 |
| Shewanella loihica PV-4 | 0.76 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.66 | Shew_2200 | | imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) | 0.99 | 3 |
| Shewanella amazonensis SB2B | 0.75 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.64 | Sama_1944 | | imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) | 0.96 | 28 |
| Shewanella sp. ANA-3 | 0.75 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.63 | Shewana3_1851 | | imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) | 0.98 | 3 |
| Shewanella oneidensis MR-1 | 0.75 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.63 | SO2071 | hisB | imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) | 0.96 | 24 |
| Alteromonas macleodii MIT1002 | 0.70 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | 0.65 | MIT1002_02635 | | Histidine biosynthesis bifunctional protein HisB | low | > 70 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.36 | Xcc-8004.4336.1 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.53 | Xcc-8004.2946.1 | | Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) | low | > 74 |
| Rhodanobacter sp. FW510-T8 | 0.35 | OKGIIK_11830 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.52 | OKGIIK_04960 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 52 |
| Rhodanobacter denitrificans FW104-10B01 | 0.35 | LRK54_RS12030 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.53 | LRK54_RS01595 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.35 | LRK55_RS11765 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.53 | LRK55_RS01375 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 63 |
| Dyella japonica UNC79MFTsu3.2 | 0.35 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.54 | ABZR86_RS06720 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | 0.94 | 37 |
| Lysobacter sp. OAE881 | 0.34 | ABIE51_RS16490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.54 | ABIE51_RS13315 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 62 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.22 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.43 | ABZR88_RS06870 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 71 |
| Parabacteroides merdae CL09T00C40 | 0.21 | HMPREF1078_RS07860 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.45 | HMPREF1078_RS02440 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 61 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.21 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.44 | Echvi_2457 | | histidinol-phosphatase | 0.86 | 34 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.21 | CA265_RS23445 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | CA265_RS03625 | | bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase | 0.94 | 27 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.20 | CA264_16780 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.47 | CA264_05040 | | bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase | low | > 74 |
| Phocaeicola dorei CL03T12C01 | 0.19 | ABI39_RS15570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.44 | ABI39_RS11845 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 72 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.18 | BT3821 | | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.46 | BT0203 | | histidine biosynthesis bifunctional protein hisB (NCBI ptt file) | low | > 81 |
| Phocaeicola vulgatus CL09T03C04 | 0.18 | HMPREF1058_RS01490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.44 | HMPREF1058_RS15885 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 67 |
| Bacteroides stercoris CC31F | 0.17 | HMPREF1181_RS00120 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.46 | HMPREF1181_RS04850 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 56 |
| Bacteroides ovatus ATCC 8483 | 0.15 | BACOVA_03666 | | methylenetetrahydrofolate reductase (NAD(P)H) | 0.46 | BACOVA_01232 | | histidinol-phosphatase | low | > 94 |
Not shown: 53 genomes with orthologs for b3941 only; 0 genomes with orthologs for b2022 only