Conservation of cofitness between b2020 and b2022 in Escherichia coli BW25113

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2020 hisD histidinol dehydrogenase (NCBI) 1.0 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.97 1
Escherichia coli ECOR27 0.99 NOLOHH_15830 hisD Histidinol dehydrogenase 1.00 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.64 13
Escherichia coli BL21 0.99 ECD_01922 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase 0.99 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase 0.31 36
Escherichia coli ECRC62 0.99 BNILDI_14740 hisD Histidinol dehydrogenase 0.99 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS11945 histidinol dehydrogenase 0.99 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECOR38 0.99 HEPCGN_03220 hisD Histidinol dehydrogenase 0.99 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_01680 Histidinol dehydrogenase 0.99 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 73
Escherichia fergusonii Becca 0.98 EFB2_01836 Histidinol dehydrogenase 0.99 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli ECRC102 0.98 NIAGMN_22460 hisD Histidinol dehydrogenase 1.00 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC101 0.98 MCAODC_20425 hisD Histidinol dehydrogenase 1.00 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC101 0.98 OKFHMN_24515 hisD Histidinol dehydrogenase 1.00 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC99 0.98 KEDOAH_03635 hisD Histidinol dehydrogenase 1.00 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC98 0.98 JDDGAC_28625 hisD Histidinol dehydrogenase 1.00 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF3912 Histidinol dehydrogenase (EC 1.1.1.23) 0.96 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0539 histidinol dehydrogenase 0.91 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.96 2
Enterobacter sp. TBS_079 0.89 MPMX20_03002 Histidinol dehydrogenase 0.92 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.98 2
Klebsiella michiganensis M5al 0.88 BWI76_RS18925 histidinol dehydrogenase 0.88 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.94 1
Serratia liquefaciens MT49 0.85 IAI46_08210 histidinol dehydrogenase 0.84 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.89 5
Pantoea sp. MT58 0.82 IAI47_07090 histidinol dehydrogenase 0.82 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.98 3
Erwinia tracheiphila SCR3 0.81 LU632_RS08945 hisD histidinol dehydrogenase 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.94 2
Dickeya dadantii 3937 0.80 DDA3937_RS09735 histidinol dehydrogenase 0.84 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.97 2
Pectobacterium carotovorum WPP14 0.80 HER17_RS12230 histidinol dehydrogenase 0.83 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.98 5
Dickeya dianthicola 67-19 0.79 HGI48_RS09745 histidinol dehydrogenase 0.84 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Dickeya dianthicola ME23 0.79 DZA65_RS10055 histidinol dehydrogenase 0.84 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 3
Rahnella sp. WP5 0.79 EX31_RS11440 histidinol dehydrogenase 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.98 1
Vibrio cholerae E7946 ATCC 55056 0.63 CSW01_05750 histidinol dehydrogenase 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Shewanella amazonensis SB2B 0.59 Sama_1942 hisD histidinol dehydrogenase (RefSeq) 0.64 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.99 4
Shewanella loihica PV-4 0.57 Shew_2198 histidinol dehydrogenase (RefSeq) 0.66 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.94 11
Shewanella oneidensis MR-1 0.57 SO2073 hisD histidinol dehydrogenase (NCBI ptt file) 0.63 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.98 9
Shewanella sp. ANA-3 0.56 Shewana3_1853 hisD histidinol dehydrogenase (RefSeq) 0.63 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.97 1
Alteromonas macleodii MIT1002 0.54 MIT1002_02633 Histidinol dehydrogenase 0.65 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.98 17
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS01605 histidinol dehydrogenase 0.53 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.84 3
Rhodanobacter denitrificans MT42 0.53 LRK55_RS01385 histidinol dehydrogenase 0.53 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.84 2
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS06730 histidinol dehydrogenase 0.54 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.95 41
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_04950 hisD histidinol dehydrogenase 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 52
Bacteroides ovatus ATCC 8483 0.53 BACOVA_01234 histidinol dehydrogenase 0.46 BACOVA_01232 histidinol-phosphatase 0.98 2
Bacteroides thetaiotaomicron VPI-5482 0.52 BT0201 histidinol dehydrogenase (NCBI ptt file) 0.46 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.92 13
Phocaeicola vulgatus CL09T03C04 0.51 HMPREF1058_RS15875 histidinol dehydrogenase 0.44 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.97 6
Bacteroides stercoris CC31F 0.50 HMPREF1181_RS04860 histidinol dehydrogenase 0.46 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.98 3
Phocaeicola dorei CL03T12C01 0.50 ABI39_RS11835 histidinol dehydrogenase 0.44 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.89 1
Lysobacter sp. OAE881 0.49 ABIE51_RS13325 histidinol dehydrogenase 0.54 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.88 61
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS02450 histidinol dehydrogenase 0.45 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.98 17
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.2948.1 Histidinol dehydrogenase (EC 1.1.1.23) 0.53 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.93 4
Echinicola vietnamensis KMM 6221, DSM 17526 0.47 Echvi_2459 histidinol dehydrogenase 0.44 Echvi_2457 histidinol-phosphatase 0.97 2
Pontibacter actiniarum KMM 6156, DSM 19842 0.45 CA264_05030 histidinol dehydrogenase 0.47 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.58 1
Pedobacter sp. GW460-11-11-14-LB5 0.44 CA265_RS03635 histidinol dehydrogenase 0.42 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.97 1
Mucilaginibacter yixingensis YX-36 DSM 26809 0.44 ABZR88_RS06880 histidinol dehydrogenase 0.43 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —

Not shown: 55 genomes with orthologs for b2020 only; 0 genomes with orthologs for b2022 only