Conservation of cofitness between b2019 and b2022 in Escherichia coli BW25113

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2019 hisG ATP phosphoribosyltransferase (NCBI) 1.0 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.96 5
Escherichia coli ECRC62 1.00 BNILDI_14745 hisG ATP phosphoribosyltransferase 0.99 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01681 ATP phosphoribosyltransferase 0.99 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 73
Escherichia coli Nissle 1917 1.00 ECOLIN_RS11940 ATP phosphoribosyltransferase 0.99 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia fergusonii Becca 1.00 EFB2_01837 ATP phosphoribosyltransferase 0.99 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli ECOR27 1.00 NOLOHH_15835 hisG ATP phosphoribosyltransferase 1.00 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 57
Escherichia coli ECOR38 1.00 HEPCGN_03225 hisG ATP phosphoribosyltransferase 0.99 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 85
Escherichia coli ECRC99 1.00 KEDOAH_03630 hisG ATP phosphoribosyltransferase 1.00 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC101 1.00 OKFHMN_24520 hisG ATP phosphoribosyltransferase 1.00 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC101 1.00 MCAODC_20420 hisG ATP phosphoribosyltransferase 1.00 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC98 1.00 JDDGAC_28630 hisG ATP phosphoribosyltransferase 1.00 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC102 1.00 NIAGMN_22465 hisG ATP phosphoribosyltransferase 1.00 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli BL21 1.00 ECD_01921 ATP phosphoribosyltransferase 0.99 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase low > 60
Enterobacter sp. TBS_079 0.97 MPMX20_03001 ATP phosphoribosyltransferase 0.92 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.98 3
Enterobacter asburiae PDN3 0.97 EX28DRAFT_0540 ATP phosphoribosyltransferase 0.91 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.95 3
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3913 ATP phosphoribosyltransferase (EC 2.4.2.17) 0.96 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 78
Klebsiella michiganensis M5al 0.95 BWI76_RS18920 ATP phosphoribosyltransferase 0.88 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.91 2
Pectobacterium carotovorum WPP14 0.91 HER17_RS12225 ATP phosphoribosyltransferase 0.83 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.97 4
Dickeya dianthicola 67-19 0.91 HGI48_RS09750 ATP phosphoribosyltransferase 0.84 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.66 17
Rahnella sp. WP5 0.91 EX31_RS11435 ATP phosphoribosyltransferase 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.86 38
Dickeya dianthicola ME23 0.91 DZA65_RS10060 ATP phosphoribosyltransferase 0.84 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.79 13
Dickeya dadantii 3937 0.90 DDA3937_RS09740 ATP phosphoribosyltransferase 0.84 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 10
Serratia liquefaciens MT49 0.90 IAI46_08215 ATP phosphoribosyltransferase 0.84 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.91 5
Erwinia tracheiphila SCR3 0.89 LU632_RS08950 hisG ATP phosphoribosyltransferase 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.93 4
Pantoea sp. MT58 0.88 IAI47_07095 ATP phosphoribosyltransferase 0.82 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.98 2
Shewanella sp. ANA-3 0.70 Shewana3_1854 hisG ATP phosphoribosyltransferase (RefSeq) 0.63 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.87 15
Shewanella oneidensis MR-1 0.70 SO2074 hisG ATP phosphoribosyltransferase (NCBI ptt file) 0.63 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.98 11
Shewanella loihica PV-4 0.69 Shew_2197 hisG ATP phosphoribosyltransferase (RefSeq) 0.66 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.99 1
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_05745 ATP phosphoribosyltransferase 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Shewanella amazonensis SB2B 0.67 Sama_1941 hisG ATP phosphoribosyltransferase (RefSeq) 0.64 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.96 6
Alteromonas macleodii MIT1002 0.66 MIT1002_02632 ATP phosphoribosyltransferase 0.65 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.95 15
Pontibacter actiniarum KMM 6156, DSM 19842 0.45 CA264_05025 ATP phosphoribosyltransferase 0.47 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2460 ATP phosphoribosyltransferase 0.44 Echvi_2457 histidinol-phosphatase 0.95 5
Bacteroides stercoris CC31F 0.43 HMPREF1181_RS04865 ATP phosphoribosyltransferase 0.46 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 6
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS15870 ATP phosphoribosyltransferase 0.44 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 8
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS11830 ATP phosphoribosyltransferase 0.44 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.82 1
Lysobacter sp. OAE881 0.42 ABIE51_RS13330 ATP phosphoribosyltransferase 0.54 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.85 57
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS02455 ATP phosphoribosyltransferase 0.45 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.87 37
Bacteroides thetaiotaomicron VPI-5482 0.42 BT0200 ATP phosphoribosyltransferase (NCBI ptt file) 0.46 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.91 16
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS06885 ATP phosphoribosyltransferase 0.43 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS06735 ATP phosphoribosyltransferase 0.54 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 46
Rhodanobacter denitrificans MT42 0.39 LRK55_RS01390 ATP phosphoribosyltransferase 0.53 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 63
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS01610 ATP phosphoribosyltransferase 0.53 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.49 11
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_04945 hisG ATP phosphoribosyltransferase 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Bacteroides ovatus ATCC 8483 0.39 BACOVA_01235 ATP phosphoribosyltransferase 0.46 BACOVA_01232 histidinol-phosphatase 0.98 1
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS03640 ATP phosphoribosyltransferase 0.42 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.95 2
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.2949.1 ATP phosphoribosyltransferase (EC 2.4.2.17) 0.53 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.75 5

Not shown: 9 genomes with orthologs for b2019 only; 0 genomes with orthologs for b2022 only