Conservation of cofitness between b1780 and b0889 in Escherichia coli BW25113

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1780 yeaD orf, hypothetical protein (VIMSS) 1.0 b0889 lrp DNA-binding transcriptional dual regulator, leucine-binding (NCBI) 0.18 11
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01952 Putative glucose-6-phosphate 1-epimerase 1.00 OHPLBJKB_02779 Leucine-responsive regulatory protein low > 73
Escherichia coli ECOR27 0.99 NOLOHH_17255 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 NOLOHH_22145 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli ECRC62 0.99 BNILDI_16040 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 BNILDI_20400 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli BL21 0.99 ECD_01749 D-hexose-6-phosphate epimerase-like protein 1.00 ECD_00893 leucine-responsive global transcriptional regulator low > 60
Escherichia coli Nissle 1917 0.98 ECOLIN_RS09925 D-hexose-6-phosphate mutarotase 1.00 ECOLIN_RS04730 leucine-responsive transcriptional regulator Lrp
Escherichia fergusonii Becca 0.98 EFB2_02214 Putative glucose-6-phosphate 1-epimerase 1.00 EFB2_03172 Leucine-responsive regulatory protein low > 86
Escherichia coli ECOR38 0.98 HEPCGN_05115 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 HEPCGN_22935 lrp leucine-responsive transcriptional regulator Lrp low > 85
Escherichia coli ECRC99 0.97 KEDOAH_01385 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 KEDOAH_22160 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli ECRC102 0.97 NIAGMN_01340 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 NIAGMN_03295 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli ECRC101 0.97 MCAODC_18685 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 MCAODC_24965 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli ECRC101 0.97 OKFHMN_26725 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 OKFHMN_05575 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli ECRC98 0.97 JDDGAC_01300 yeaD Putative glucose-6-phosphate 1-epimerase 1.00 JDDGAC_09385 lrp leucine-responsive transcriptional regulator Lrp
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.82 GFF3477 Aldose 1-epimerase family protein YeaD 1.00 GFF4893 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 78
Klebsiella michiganensis M5al 0.80 BWI76_RS11500 D-hexose-6-phosphate mutarotase 1.00 BWI76_RS09655 leucine-responsive regulatory protein low > 92
Enterobacter asburiae PDN3 0.72 EX28DRAFT_1774 Uncharacterized enzymes related to aldose 1-epimerase 1.00 EX28DRAFT_2043 transcriptional regulator, AsnC family low > 76
Enterobacter sp. TBS_079 0.72 MPMX20_01843 Putative glucose-6-phosphate 1-epimerase 1.00 MPMX20_01551 Leucine-responsive regulatory protein low > 85
Serratia liquefaciens MT49 0.58 IAI46_14360 D-hexose-6-phosphate mutarotase 0.98 IAI46_08555 leucine-responsive transcriptional regulator Lrp low > 86
Pectobacterium carotovorum WPP14 0.58 HER17_RS11135 D-hexose-6-phosphate mutarotase 0.98 HER17_RS12360 leucine-responsive transcriptional regulator Lrp low > 75
Dickeya dianthicola 67-19 0.57 HGI48_RS10270 D-hexose-6-phosphate mutarotase 0.98 HGI48_RS09605 leucine-responsive transcriptional regulator Lrp low > 71
Dickeya dianthicola ME23 0.57 DZA65_RS10745 D-hexose-6-phosphate mutarotase 0.98 DZA65_RS09915 leucine-responsive transcriptional regulator Lrp low > 75
Pantoea sp. MT58 0.57 IAI47_08940 D-hexose-6-phosphate mutarotase 0.97 IAI47_12915 leucine-responsive transcriptional regulator Lrp low > 76
Rahnella sp. WP5 0.56 EX31_RS06275 D-hexose-6-phosphate mutarotase 0.98 EX31_RS18530 leucine-responsive transcriptional regulator Lrp low > 89
Dickeya dadantii 3937 0.56 DDA3937_RS10260 D-hexose-6-phosphate mutarotase 0.98 DDA3937_RS09590 leucine-responsive transcriptional regulator Lrp low > 74
Erwinia tracheiphila SCR3 0.54 LU632_RS13000 D-hexose-6-phosphate mutarotase 0.97 LU632_RS09740 lrp leucine-responsive transcriptional regulator Lrp low > 74
Vibrio cholerae E7946 ATCC 55056 0.32 CSW01_09980 D-hexose-6-phosphate mutarotase 0.92 CSW01_09530 leucine-responsive transcriptional regulator Lrp
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_750 Aldose 1-epimerase 0.58 PfGW456L13_811 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 87
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_09920 aldose epimerase 0.58 AO353_09160 AsnC family transcriptional regulator low > 101
Pseudomonas putida KT2440 0.25 PP_5332 conserved protein of unknown function 0.58 PP_5271 DNA-binding transcriptional dual regulator, leucine-binding low > 96
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_11060 aldose epimerase 0.58 AO356_12615 AsnC family transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_2031 Aldose 1-epimerase 0.58 Pf1N1B4_2143 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 87
Pseudomonas sp. RS175 0.24 PFR28_04492 Putative glucose-6-phosphate 1-epimerase 0.58 PFR28_04400 Leucine-responsive regulatory protein low > 88
Marinobacter adhaerens HP15 0.24 HP15_1887 aldose 1-epimerase family protein 0.47 HP15_2690 transcriptional regulator, AsnC family low > 73
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_4078 Aldose 1-epimerase 0.58 Pf6N2E2_4390 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 103
Shewanella oneidensis MR-1 0.24 SO2769 conserved hypothetical protein (NCBI ptt file) 0.80 SO2305 lrp leucine-responsive regulatory protein (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.24 Shewana3_2553 aldose 1-epimerase (RefSeq) 0.80 Shewana3_2049 leucine-responsive transcriptional regulator (RefSeq) low > 73
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_5044 Aldose 1-epimerase 0.59 Psyr_0234 transcriptional regulator, AsnC family low > 86
Shewanella amazonensis SB2B 0.24 Sama_2115 hypothetical protein (RefSeq) 0.82 Sama_1771 leucine-responsive transcriptional regulator (RefSeq) 0.28 54
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_5044 Aldose 1-epimerase 0.59 Psyr_0234 transcriptional regulator, AsnC family low > 86
Shewanella loihica PV-4 0.23 Shew_2165 aldose 1-epimerase (RefSeq) 0.83 Shew_2025 leucine-responsive transcriptional regulator (RefSeq) low > 60
Pseudomonas stutzeri RCH2 0.23 Psest_0135 Uncharacterized enzymes related to aldose 1-epimerase 0.57 Psest_3794 Transcriptional regulators low > 67
Pseudomonas simiae WCS417 0.23 PS417_28100 glucose-6-phosphate 1-epimerase [EC: 5.1.3.15] (from data) 0.58 PS417_27710 AsnC family transcriptional regulator low > 88
Pseudomonas sp. S08-1 0.22 OH686_13395 Aldose 1-epimerase family protein YeaD 0.58 OH686_13680 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 80
Pseudomonas fluorescens SBW25-INTG 0.22 PFLU_RS29785 D-hexose-6-phosphate mutarotase 0.58 PFLU_RS29385 AsnC family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.22 PFLU_RS29785 D-hexose-6-phosphate mutarotase 0.58 PFLU_RS29385 AsnC family transcriptional regulator low > 109
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS07395 aldose 1-epimerase 0.59 HSERO_RS00865 AsnC family transcriptional regulator low > 78
Alteromonas macleodii MIT1002 0.19 MIT1002_02402 Putative glucose-6-phosphate 1-epimerase 0.66 MIT1002_02181 Leucine-responsive regulatory protein low > 70

Not shown: 1 genomes with orthologs for b1780 only; 44 genomes with orthologs for b0889 only