| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
|---|
| | Shewanella oneidensis MR-1 | SO2098 | hyaB | quinone-reactive Ni/Fe hydrogenase, large subunit (NCBI ptt file) | insig. | 100 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_1879 | | nickel-dependent hydrogenase, large subunit (RefSeq) | insig. | 98 | 100 |
| o | Shewanella amazonensis SB2B | Sama_1678 | | hydrogenase large chain (RefSeq) | insig. | 92 | 100 |
| o | Shewanella loihica PV-4 | Shew_1764 | | nickel-dependent hydrogenase, large subunit (RefSeq) | insig. | 91 | 100 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS17250 | | hydrogenase 2 large subunit | cofit | 46 | 99 |
| o | Escherichia coli ECRC98 | JDDGAC_22655 | hybC | hydrogenase 2 large subunit | insig. | 46 | 99 |
| o | Escherichia coli BL21 | ECD_02870 | | hydrogenase 2, large subunit | cofit | 46 | 99 |
| o | Escherichia fergusonii Becca | EFB2_00813 | | Hydrogenase-2 large chain | cofit | 46 | 99 |
| o | Escherichia coli ECOR27 | NOLOHH_10795 | hybC | hydrogenase 2 large subunit | insig. | 46 | 99 |
| o | Escherichia coli ECOR38 | HEPCGN_17880 | hybC | hydrogenase 2 large subunit | insig. | 46 | 99 |
| o | Escherichia coli ECRC100 | OKFHMN_19020 | hybC | hydrogenase 2 large subunit | cofit | 46 | 99 |
| o | Escherichia coli ECRC101 | MCAODC_09535 | hybC | hydrogenase 2 large subunit | insig. | 46 | 99 |
| o | Escherichia coli ECRC102 | NIAGMN_16785 | hybC | hydrogenase 2 large subunit | insig. | 46 | 99 |
| o | Escherichia coli ECRC62 | BNILDI_00720 | hybC | hydrogenase 2 large subunit | insig. | 46 | 99 |
| o | Escherichia coli ECRC99 | KEDOAH_09125 | hybC | hydrogenase 2 large subunit | no data | 46 | 99 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00705 | | Hydrogenase-2 large chain | insig. | 46 | 99 |
| o | Escherichia coli BW25113 | b2994 | hybC | hydrogenase 2, large subunit (NCBI) | sig. | 46 | 99 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3105 | | Uptake hydrogenase large subunit (EC 1.12.99.6) | insig. | 45 | 99 |
| o | Desulfovibrio vulgaris Miyazaki F | DvMF_0270 | | nickel-dependent hydrogenase large subunit (RefSeq) | insig. | 45 | 99 |
| o | Desulfovibrio vulgaris Hildenborough JW710 | DVU1922 | hynA-1 | periplasmic [NiFe] hydrogenase, large subunit, isozyme 1 (TIGR) | insig. | 45 | 98 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2524 | | Uptake hydrogenase large subunit (EC 1.12.99.6) | insig. | 44 | 99 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS08335 | | nickel-dependent hydrogenase large subunit | insig. | 45 | 97 |
| o | Rhodopseudomonas palustris CGA009 | TX73_004960 | | nickel-dependent hydrogenase large subunit | insig. | 45 | 99 |
| o | Dickeya dadantii 3937 | DDA3937_RS14240 | | hydrogenase 2 large subunit | insig. | 45 | 99 |
| o | Dickeya dianthicola ME23 | DZA65_RS14890 | | hydrogenase 2 large subunit | insig. | 45 | 99 |
| o | Dickeya dianthicola 67-19 | HGI48_RS14215 | | hydrogenase 2 large subunit | insig. | 45 | 99 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2229 | | Uptake hydrogenase large subunit (EC 1.12.99.6) | insig. | 43 | 99 |
| o | Rhodospirillum rubrum S1H | Rru_A1162 | | Nickel-dependent hydrogenase, large subunit (NCBI) | insig. | 44 | 97 |
| o | Dechlorosoma suillum PS | Dsui_3009 | | Ni,Fe-hydrogenase I large subunit | insig. | 44 | 97 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS20390 | | hydrogenase 2 large subunit | insig. | 44 | 99 |
| o | Variovorax sp. OAS795 | ABID97_RS13680 | | nickel-dependent hydrogenase large subunit | insig. | 43 | 99 |
| o | Xanthobacter sp. DMC5 | GFF4443 | | Uptake hydrogenase large subunit | insig. | 44 | 99 |
| o | Azospirillum sp. SherDot2 | MPMX19_05287 | | Uptake hydrogenase large subunit | insig. | 42 | 99 |
| o | Alteromonas macleodii MIT1002 | MIT1002_00275 | | Hydrogenase-1 large chain | insig. | 41 | 99 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1733 | | nickel-dependent hydrogenase large subunit (RefSeq) | insig. | 42 | 99 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS05115 | | Ni/Fe-hydrogenase large subunit | no data | 40 | 99 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2526 | hynA-2 | periplasmic [NiFe] hydrogenase, large subunit, isozyme 2 (TIGR) | insig. | 43 | 96 |
| | Escherichia coli BL21 | ECD_00976 | | hydrogenase 1, large subunit | insig. | 40 | 99 |
| | Escherichia coli ECOR27 | NOLOHH_21710 | hyaB | Ni/Fe-hydrogenase large subunit | insig. | 40 | 99 |
| | Escherichia coli ECOR38 | HEPCGN_23365 | hyaB | Ni/Fe-hydrogenase large subunit | insig. | 40 | 99 |
| | Escherichia coli ECRC62 | BNILDI_19875 | hyaB | Ni/Fe-hydrogenase large subunit | insig. | 40 | 99 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02693 | | Hydrogenase-1 large chain | insig. | 40 | 99 |
| | Escherichia coli BW25113 | b0973 | hyaB | hydrogenase 1, large subunit (NCBI) | insig. | 40 | 99 |
| | Escherichia fergusonii Becca | EFB2_03098 | | Hydrogenase-1 large chain | insig. | 40 | 99 |
| | Escherichia coli ECRC100 | OKFHMN_04805 | hyaB | Ni/Fe-hydrogenase large subunit | insig. | 40 | 99 |
| | Escherichia coli ECRC101 | MCAODC_24190 | hyaB | Ni/Fe-hydrogenase large subunit | insig. | 40 | 99 |
| | Escherichia coli ECRC102 | NIAGMN_23045 | hyaB | Ni/Fe-hydrogenase large subunit | insig. | 40 | 99 |
| | Escherichia coli ECRC98 | JDDGAC_08415 | hyaB | Ni/Fe-hydrogenase large subunit | insig. | 40 | 99 |
| | Escherichia coli ECRC99 | KEDOAH_22940 | hyaB | Ni/Fe-hydrogenase large subunit | no data | 40 | 99 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2788 | | Uptake hydrogenase large subunit (EC 1.12.99.6) | insig. | 40 | 99 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1918 | hysA | periplasmic [NiFeSe] hydrogenase, large subunit, selenocysteine-containing (TIGR) | strong | 33 | 96 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0273 | | nickel-dependent hydrogenase large subunit (RefSeq) | cofit | 33 | 95 |
| | Variovorax sp. OAS795 | ABID97_RS13580 | | nickel-dependent hydrogenase large subunit | insig. | 29 | 96 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS05660 | | Ni,Fe-hydrogenase I large subunit | cofit | 28 | 99 |
| | Dechlorosoma suillum PS | Dsui_1152 | | Ni,Fe-hydrogenase I large subunit | cofit | 28 | 97 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2208 | | Uptake hydrogenase large subunit (EC 1.12.99.6) | insig. | 28 | 96 |
| | Xanthobacter sp. DMC5 | GFF2241 | | Periplasmic [NiFeSe] hydrogenase large subunit | insig. | 26 | 96 |
| | Azospirillum sp. SherDot2 | MPMX19_05298 | | Periplasmic [NiFeSe] hydrogenase large subunit | insig. | 26 | 88 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09800 | | uptake hydrogenase | insig. | 29 | 60 |
| | Methanococcus maripaludis JJ | MMJJ_RS00865 | | Ni/Fe hydrogenase subunit alpha | insig. | 24 | 98 |
| | Methanococcus maripaludis S2 | MMP_RS04285 | | Ni/Fe hydrogenase subunit alpha | sig. | 22 | 98 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09725 | | Ni/Fe hydrogenase subunit alpha | insig. | 24 | 97 |
| | Methanococcus maripaludis S2 | MMP_RS08725 | | Ni/Fe hydrogenase subunit alpha | insig. | 37 | 20 |
| | Methanococcus maripaludis JJ | MMJJ_RS05635 | | Ni/Fe hydrogenase subunit alpha | no data | 37 | 20 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_2555 | hoxH | NAD-reducing hydrogenase HoxS beta subunit | insig. | 31 | 28 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17180 | | Ni/Fe hydrogenase subunit alpha | insig. | 31 | 26 |
| | Dechlorosoma suillum PS | Dsui_3027 | | coenzyme F420-reducing hydrogenase, alpha subunit | cofit | 30 | 23 |
| | Methanococcus maripaludis JJ | MMJJ_RS07235 | | coenzyme F420 hydrogenase subunit alpha | strong | 38 | 19 |
| | Methanococcus maripaludis S2 | MMP_RS07120 | | coenzyme F420 hydrogenase subunit alpha | strong | 38 | 18 |
| | Methanococcus maripaludis JJ | MMJJ_RS00880 | | coenzyme F420 hydrogenase subunit alpha | insig. | 36 | 19 |
| | Methanococcus maripaludis S2 | MMP_RS04270 | | coenzyme F420 hydrogenase subunit alpha | insig. | 36 | 19 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09800 | | uptake hydrogenase | insig. | 33 | 19 |
| | Azospirillum sp. SherDot2 | MPMX19_03510 | | Formate hydrogenlyase subunit 5 | insig. | 34 | 18 |
| | Escherichia coli ECOR27 | NOLOHH_12435 | hycE | formate hydrogenlyase subunit HycE | insig. | 32 | 18 |
| | Escherichia coli ECRC100 | OKFHMN_20590 | hycE | formate hydrogenlyase subunit HycE | cofit | 32 | 18 |
| | Escherichia coli ECRC101 | MCAODC_11115 | hycE | formate hydrogenlyase subunit HycE | insig. | 32 | 18 |
| | Escherichia coli ECRC102 | NIAGMN_18360 | hycE | formate hydrogenlyase subunit HycE | cofit | 32 | 18 |
| | Escherichia coli ECRC62 | BNILDI_10985 | hycE | formate hydrogenlyase subunit HycE | insig. | 32 | 18 |
| | Escherichia coli ECRC98 | JDDGAC_24255 | hycE | formate hydrogenlyase subunit HycE | insig. | 32 | 18 |
| | Escherichia coli ECRC99 | KEDOAH_07545 | hycE | formate hydrogenlyase subunit HycE | no data | 32 | 18 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS15205 | | formate hydrogenlyase subunit HycE | insig. | 32 | 18 |
| | Escherichia coli BL21 | ECD_02571 | | hydrogenase 3, large subunit | insig. | 32 | 18 |
| | Escherichia fergusonii Becca | EFB2_01202 | | Formate hydrogenlyase subunit 5 | cofit | 32 | 18 |
| | Escherichia coli ECOR38 | HEPCGN_19780 | hycE | formate hydrogenlyase subunit HycE | insig. | 32 | 18 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01013 | | Formate hydrogenlyase subunit 5 | insig. | 32 | 18 |
| | Escherichia coli BW25113 | b2721 | hycE | hydrogenase 3, large subunit (NCBI) | insig. | 32 | 18 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4714 | | Formate hydrogenlyase subunit 5 | cofit | 32 | 18 |
| | Serratia liquefaciens MT49 | IAI46_12520 | | hydrogenase large subunit | insig. | 32 | 18 |
| | Methanococcus maripaludis S2 | MMP_RS07520 | | nickel-dependent hydrogenase large subunit | no data | 33 | 16 |
| | Methanococcus maripaludis JJ | MMJJ_RS06840 | | nickel-dependent hydrogenase large subunit | strong | 33 | 16 |
| | Klebsiella michiganensis M5al | BWI76_RS22320 | | hydrogenase 3 large subunit | insig. | 31 | 18 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_02990 | | formate hydrogenlyase subunit HycE | insig. | 31 | 18 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS18820 | hycE;inference=COORDINATES | formate hydrogenlyase subunit HycE | insig. | 31 | 18 |
| | Escherichia coli ECOR27 | NOLOHH_13525 | hyfG | hydrogenase 4 catalytic subunit HyfG | insig. | 31 | 18 |
| | Escherichia coli ECRC100 | OKFHMN_21870 | hyfG | hydrogenase 4 catalytic subunit HyfG | insig. | 31 | 18 |
| | Escherichia coli ECRC101 | MCAODC_12400 | hyfG | hydrogenase 4 catalytic subunit HyfG | insig. | 31 | 18 |
| | Escherichia coli ECRC102 | NIAGMN_19640 | hyfG | hydrogenase 4 catalytic subunit HyfG | insig. | 31 | 18 |
| | Escherichia coli ECRC98 | JDDGAC_25815 | hyfG | hydrogenase 4 catalytic subunit HyfG | insig. | 31 | 18 |
| | Escherichia coli ECRC99 | KEDOAH_06350 | hyfG | hydrogenase 4 catalytic subunit HyfG | no data | 31 | 18 |
| | Escherichia coli BL21 | ECD_02379 | | hydrogenase 4, subunit | insig. | 31 | 18 |
| | Escherichia coli ECOR38 | HEPCGN_21040 | hyfG | hydrogenase 4 catalytic subunit HyfG | insig. | 31 | 18 |
| | Escherichia coli ECRC62 | BNILDI_12330 | hyfG | hydrogenase 4 catalytic subunit HyfG | insig. | 31 | 18 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01239 | | Hydrogenase-4 component G | insig. | 31 | 18 |
| | Escherichia coli BW25113 | b2487 | hyfG | hydrogenase 4, subunit (NCBI) | insig. | 31 | 18 |
| | Rahnella sp. WP5 | EX31_RS19920 | | hydrogenase large subunit | insig. | 31 | 18 |
| | Enterobacter sp. TBS_079 | MPMX20_03606 | | Formate hydrogenlyase subunit 5 | insig. | 30 | 18 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2812 | | Ni,Fe-hydrogenase III large subunit | insig. | 30 | 18 |
| | Dickeya dadantii 3937 | DDA3937_RS07445 | | hydrogenase large subunit | insig. | 30 | 18 |
| | Dickeya dianthicola 67-19 | HGI48_RS07320 | | hydrogenase large subunit | insig. | 30 | 18 |
| | Dickeya dianthicola ME23 | DZA65_RS07830 | | hydrogenase large subunit | insig. | 30 | 18 |
| | Rhodospirillum rubrum S1H | Rru_A0316 | | NADH-ubiquinone oxidoreductase (NCBI) | insig. | 34 | 16 |
| | Azospirillum sp. SherDot2 | MPMX19_05720 | | hypothetical protein | no data | 26 | 33 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1522 | | NADH-ubiquinone oxidoreductase chain 49kDa (RefSeq) | cofit | 25 | 16 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0430 | | Ech hydrogenase, subunit EchE, putative (TIGR) | sig. | 24 | 16 |
| | Methanococcus maripaludis JJ | MMJJ_RS00880 | | coenzyme F420 hydrogenase subunit alpha | insig. | 24 | 40 |
| | Methanococcus maripaludis S2 | MMP_RS04270 | | coenzyme F420 hydrogenase subunit alpha | insig. | 24 | 40 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS08320 | | Ni,Fe-hydrogenase I large subunit | insig. | 25 | 23 |
| | Rhodopseudomonas palustris CGA009 | TX73_005005 | | nickel-dependent hydrogenase large subunit | insig. | 28 | 25 |
| | Rhodospirillum rubrum S1H | Rru_A1425 | | NADH dehydrogenase (ubiquinone) (NCBI) | insig. | 25 | 18 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14510 | | hydrogenase expression protein HypE | insig. | 34 | 12 |
| | Methanococcus maripaludis JJ | MMJJ_RS08405 | | nickel-dependent hydrogenase large subunit | strong | 25 | 19 |
| | Methanococcus maripaludis S2 | MMP_RS05950 | | nickel-dependent hydrogenase large subunit | strong | 25 | 19 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_3189 | | NADH dehydrogenase (quinone) (RefSeq) | sig. | 30 | 15 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2291 | | carbon monoxide-induced hydrogenase CooH, putative (TIGR) | insig. | 28 | 14 |