Conservation of cofitness between Xcc-8004.1710.1 and Xcc-8004.2942.1 in Xanthomonas campestris pv. campestris strain 8004

47 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Xanthomonas campestris pv. campestris strain 8004 1.0 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 1.0 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.61 20
Lysobacter sp. OAE881 0.59 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.64 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 62
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.61 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.90 19
Rhodanobacter sp. FW510-T8 0.47 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.64 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 52
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.63 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.73 22
Rhodanobacter denitrificans MT42 0.45 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.65 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Acinetobacter radioresistens SK82 0.34 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.30 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE low > 36
Dickeya dadantii 3937 0.32 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.55 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 15
Serratia liquefaciens MT49 0.32 IAI46_21415 pyrroline-5-carboxylate reductase 0.51 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 86
Shewanella sp. ANA-3 0.32 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.52 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.91 37
Shewanella oneidensis MR-1 0.32 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.53 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.94 36
Dickeya dianthicola ME23 0.32 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.55 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Dickeya dianthicola 67-19 0.32 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.54 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Shewanella loihica PV-4 0.30 Shew_3016 pyrroline-5-carboxylate reductase (RefSeq) 0.53 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) low > 60
Rahnella sp. WP5 0.30 EX31_RS02690 pyrroline-5-carboxylate reductase 0.50 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.95 37
Vibrio cholerae E7946 ATCC 55056 0.30 CSW01_02450 pyrroline-5-carboxylate reductase 0.52 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase low > 62
Pectobacterium carotovorum WPP14 0.30 HER17_RS03805 pyrroline-5-carboxylate reductase 0.48 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Alteromonas macleodii MIT1002 0.30 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.54 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase 0.93 46
Shewanella amazonensis SB2B 0.30 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.50 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.94 31
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.30 Synpcc7942_1995 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein — —
Klebsiella michiganensis M5al 0.24 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.56 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase — —
Escherichia fergusonii Becca 0.24 EFB2_03670 Pyrroline-5-carboxylate reductase 0.50 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE low > 86
Escherichia coli ECRC102 0.24 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.50 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECOR38 0.24 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.54 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.87 12
Escherichia coli ECRC99 0.24 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.50 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC101 0.24 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.50 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.87 7
Escherichia coli ECRC98 0.24 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.50 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 86
Escherichia coli ECRC100 0.24 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.50 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.92 2
Escherichia coli Nissle 1917 0.24 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.50 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli BL21 0.24 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.54 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.55 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE low > 73
Escherichia coli BW25113 0.24 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.54 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.86 19
Escherichia coli ECOR27 0.24 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.49 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.86 46
Escherichia coli ECRC62 0.24 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.54 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.75 52
Pantoea sp. MT58 0.24 IAI47_14945 pyrroline-5-carboxylate reductase 0.53 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.83 28
Enterobacter asburiae PDN3 0.23 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.53 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.74 11
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.23 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.50 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) low > 78
Enterobacter sp. TBS_079 0.23 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.54 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.86 30
Erwinia tracheiphila SCR3 0.21 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.49 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.58 53
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_2635 pyrroline-5-carboxylate reductase 0.48 Echvi_2517 phosphoribosyl-ATP pyrophosphohydrolase 0.67 47
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.48 ABI39_RS19935 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.82 16
Pontibacter actiniarum KMM 6156, DSM 19842 0.15 CA264_07730 pyrroline-5-carboxylate reductase 0.47 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase low > 74
Phocaeicola vulgatus CL09T03C04 0.15 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.48 HMPREF1058_RS06180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.95 4
Brevundimonas sp. GW460-12-10-14-LB2 0.15 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.48 A4249_RS10720 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.97 33
Bacteroides ovatus ATCC 8483 0.15 BACOVA_03587 pyrroline-5-carboxylate reductase 0.50 BACOVA_00218 phosphoribosyl-ATP diphosphatase 0.86 40
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.50 HMPREF1181_RS11065 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.92 26
Mucilaginibacter yixingensis YX-36 DSM 26809 0.14 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.52 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Bacteroides thetaiotaomicron VPI-5482 0.13 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.50 BT1377 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) 0.92 7

Not shown: 49 genomes with orthologs for Xcc-8004.1710.1 only; 2 genomes with orthologs for Xcc-8004.2942.1 only