Conservation of cofitness between Rv0234c and Rv2899c in Mycobacterium tuberculosis H37Rv

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Mycobacterium tuberculosis H37Rv 1.0 Rv0234c Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 1.0 Rv2899c Possible FdhD protein homolog 0.32 18
Sphingomonas koreensis DSMZ 15582 0.43 Ga0059261_1006 NAD-dependent aldehyde dehydrogenases 0.19 Ga0059261_3871 formate dehydrogenase family accessory protein FdhD low > 68
Xanthobacter sp. DMC5 0.41 GFF2872 Succinate semialdehyde dehydrogenase [NAD(P)+] Sad 0.20 GFF208 Sulfur carrier protein FdhD — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS05210 NAD-dependent succinate-semialdehyde dehydrogenase 0.43 ABZR88_RS07865 formate dehydrogenase accessory sulfurtransferase FdhD low > 71
Pseudomonas putida KT2440 0.39 PP_3151 NAD+-dependent succinate semialdehyde dehydrogenase 0.17 PP_0257 protein sulfur transferase low > 96
Klebsiella michiganensis M5al 0.38 BWI76_RS15205 succinate-semialdehyde dehydrogenase 0.18 BWI76_RS00475 sulfurtransferase FdhD low > 92
Paraburkholderia bryophila 376MFSha3.1 0.38 H281DRAFT_00027 succinate semialdehyde dehydrogenase (EC 1.2.1.16) 0.21 H281DRAFT_06437 FdhD protein low > 103
Pseudomonas sp. DMC3 0.38 GFF1764 Succinate semialdehyde dehydrogenase [NAD(P)+] Sad 0.18 GFF4166 Sulfur carrier protein FdhD low > 89
Pseudomonas fluorescens FW300-N1B4 0.38 Pf1N1B4_5616 Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) 0.19 Pf1N1B4_1673 Formate dehydrogenase chain D (EC 1.2.1.2) low > 87
Pseudomonas sp. BP01 0.37 JOY50_RS21630 aldehyde dehydrogenase family protein 0.17 JOY50_RS26450 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 84
Alteromonas macleodii MIT1002 0.37 MIT1002_03989 Succinate semialdehyde dehydrogenase [NAD(P)+] Sad 0.18 MIT1002_01712 formate dehydrogenase accessory protein low > 70
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_3880 Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) 0.19 PfGW456L13_408 Formate dehydrogenase chain D (EC 1.2.1.2) low > 87
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS20675 aldehyde dehydrogenase family protein 0.19 PFLU_RS01365 formate dehydrogenase accessory sulfurtransferase FdhD low > 109
Pseudomonas fluorescens SBW25 0.37 PFLU_RS20675 aldehyde dehydrogenase family protein 0.19 PFLU_RS01365 formate dehydrogenase accessory sulfurtransferase FdhD low > 109
Pseudomonas orientalis W4I3 0.37 QF045_RS20825 aldehyde dehydrogenase family protein 0.18 QF045_RS04395 formate dehydrogenase accessory sulfurtransferase FdhD low > 93
Pseudomonas sp. SVBP6 0.37 COO64_RS20795 aldehyde dehydrogenase family protein 0.17 COO64_RS00630 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 93
Pseudomonas simiae WCS417 0.37 PS417_18705 succinate dehydrogenase 0.18 PS417_01270 iron ABC transporter substrate-binding protein low > 88
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.2214.1 Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) 0.26 Xcc-8004.2194.1 Formate dehydrogenase chain D (EC 1.2.1.2) low > 74
Klebsiella pneumoniae MKP103 0.37 KDGMDA_21585 succinate-semialdehyde dehydrogenase 0.19 KDGMDA_09080 formate dehydrogenase accessory sulfurtransferase FdhD low > 95
Paraburkholderia graminis OAS925 0.37 ABIE53_001753 succinate-semialdehyde dehydrogenase 0.18 ABIE53_000787 FdhD protein low > 113
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_2394 succinate semialdehyde dehydrogenase 0.19 Psyr_4945 Formate dehydrogenase, subunit FdhD low > 86
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_2394 succinate semialdehyde dehydrogenase 0.19 Psyr_4945 Formate dehydrogenase, subunit FdhD low > 86
Pseudomonas lactucae CFBP13502 0.36 GEMAOFIL_03968 Succinate semialdehyde dehydrogenase [NAD(P)+] Sad 0.18 GEMAOFIL_00479 Sulfur carrier protein FdhD low > 96
Rahnella sp. WP5 0.36 EX31_RS23855 NAD-dependent succinate-semialdehyde dehydrogenase 0.19 EX31_RS05780 formate dehydrogenase accessory sulfurtransferase FdhD low > 89
Escherichia coli BL21 0.36 ECD_01482 succinate semialdehyde dehydrogenase, NAD(P)+-dependent 0.18 ECD_03780 formate dehydrogenase formation protein low > 61
Escherichia coli BW25113 0.36 b1525 b1525 putative aldehyde dehydrogenase (VIMSS) 0.18 b3895 fdhD formate dehydrogenase accessory protein (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.36 OHPLBJKB_02194 Succinate semialdehyde dehydrogenase [NAD(P)+] Sad 0.18 OHPLBJKB_04155 Sulfur carrier protein FdhD low > 74
Escherichia coli ECRC62 0.36 BNILDI_17240 sad succinate-semialdehyde dehydrogenase 0.18 BNILDI_05455 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 75
Escherichia coli ECRC99 0.36 KEDOAH_27320 sad succinate-semialdehyde dehydrogenase 0.18 KEDOAH_14205 fdhD formate dehydrogenase accessory sulfurtransferase FdhD — —
Escherichia coli ECOR27 0.36 NOLOHH_18760 sad succinate-semialdehyde dehydrogenase 0.18 NOLOHH_06070 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 76
Escherichia coli ECOR38 0.36 HEPCGN_26650 sad succinate-semialdehyde dehydrogenase 0.18 HEPCGN_12585 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 88
Escherichia fergusonii Becca 0.36 EFB2_02435 Succinate semialdehyde dehydrogenase [NAD(P)+] Sad 0.18 EFB2_04720 Sulfur carrier protein FdhD low > 86
Escherichia coli Nissle 1917 0.36 ECOLIN_RS08710 succinate-semialdehyde dehydrogenase 0.18 ECOLIN_RS22460 formate dehydrogenase accessory sulfurtransferase FdhD — —
Escherichia coli ECRC102 0.36 NIAGMN_25255 sad succinate-semialdehyde dehydrogenase 0.18 NIAGMN_11705 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 80
Escherichia coli ECRC98 0.36 JDDGAC_03620 sad succinate-semialdehyde dehydrogenase 0.18 JDDGAC_17575 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 87
Enterobacter sp. TBS_079 0.36 MPMX20_00625 Succinate-semialdehyde dehydrogenase [NADP(+)] 1 0.19 MPMX20_04574 Sulfur carrier protein FdhD low > 85
Escherichia coli ECRC100 0.36 OKFHMN_01110 sad succinate-semialdehyde dehydrogenase 0.18 OKFHMN_13950 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 79
Escherichia coli ECRC101 0.36 MCAODC_16815 sad succinate-semialdehyde dehydrogenase 0.18 MCAODC_04450 fdhD formate dehydrogenase accessory sulfurtransferase FdhD low > 87
Erwinia amylovora T8 0.35 OLJFJH_15845 succinate-semialdehyde dehydrogenase 0.18 OLJFJH_05050 formate dehydrogenase accessory sulfurtransferase FdhD low > 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.35 GFF2511 Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) 0.16 GFF2254 Formate dehydrogenase chain D (EC 1.2.1.2) low > 78
Enterobacter asburiae PDN3 0.35 EX28DRAFT_3530 NAD-dependent aldehyde dehydrogenases 0.19 EX28DRAFT_4379 formate dehydrogenase family accessory protein FdhD low > 76
Pantoea agglomerans CFBP13505 P0401 0.35 PagCFBP13505_RS07280 aldehyde dehydrogenase family protein 0.20 PagCFBP13505_RS15775 formate dehydrogenase accessory sulfurtransferase FdhD low > 74
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS04460 NAD-dependent succinate-semialdehyde dehydrogenase 0.24 ABZR86_RS03590 formate dehydrogenase accessory sulfurtransferase FdhD low > 74
Pantoea sp. MT58 0.35 IAI47_21330 aldehyde dehydrogenase family protein 0.19 IAI47_18740 formate dehydrogenase accessory sulfurtransferase FdhD low > 76
Paraburkholderia sabiae LMG 24235 0.35 QEN71_RS38495 NAD-dependent succinate-semialdehyde dehydrogenase 0.20 QEN71_RS02080 formate dehydrogenase accessory sulfurtransferase FdhD low > 153
Sphingobium sp. HT1-2 0.33 GFF4977 Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) 0.16 GFF769 Sulfur carrier protein FdhD low > 95
Pseudomonas fluorescens FW300-N2E3 0.27 AO353_24475 aldehyde dehydrogenase 0.20 AO353_11830 formate dehydrogenase family accessory protein FdhD low > 101
Pseudomonas segetis P6 0.26 MPMX49_00504 Glutarate-semialdehyde dehydrogenase 0.16 MPMX49_04389 Sulfur carrier protein FdhD low > 75
Burkholderia phytofirmans PsJN 0.26 BPHYT_RS30285 succinate-semialdehyde dehydrogenase 0.20 BPHYT_RS03240 formate dehydrogenase accessory protein FdhD low > 109
Pseudomonas sp. RS175 0.26 PFR28_04755 Glutarate-semialdehyde dehydrogenase 0.20 PFR28_04882 Sulfur carrier protein FdhD low > 88
Herbaspirillum seropedicae SmR1 0.25 HSERO_RS07235 aldehyde dehydrogenase 0.21 HSERO_RS07435 formate dehydrogenase accessory protein FdhD low > 78

Not shown: 14 genomes with orthologs for Rv0234c only; 37 genomes with orthologs for Rv2899c only