| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Pseudomonas syringae pv. syringae B728a | 1.0 | Psyr_0344 | | Secretion protein HlyD | 1.0 | Psyr_1350 | | site-2 protease, Metallo peptidase, MEROPS family M50B | 0.45 | 12 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 1.00 | Psyr_0344 | | Secretion protein HlyD | 1.00 | Psyr_1350 | | site-2 protease, Metallo peptidase, MEROPS family M50B | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.66 | PfGW456L13_459 | | Efflux transporter, RND family, MFP subunit | 0.84 | PfGW456L13_4701 | | Membrane-associated zinc metalloprotease | low | > 87 |
| Pseudomonas lactucae CFBP13502 | 0.66 | GEMAOFIL_00434 | | Multidrug resistance protein MdtE | 0.83 | GEMAOFIL_01419 | | Regulator of sigma-E protease RseP | low | > 96 |
| Pseudomonas simiae WCS417 | 0.66 | PS417_01040 | | RND transporter | 0.84 | PS417_06245 | | zinc metallopeptidase RseP | low | > 88 |
| Pseudomonas orientalis W4I3 | 0.66 | QF045_RS04165 | | efflux RND transporter periplasmic adaptor subunit | 0.83 | QF045_RS09090 | | sigma E protease regulator RseP | low | > 93 |
| Pseudomonas fluorescens SBW25 | 0.66 | PFLU_RS01145 | | efflux RND transporter periplasmic adaptor subunit | 0.85 | PFLU_RS06310 | | sigma E protease regulator RseP | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.66 | PFLU_RS01145 | | efflux RND transporter periplasmic adaptor subunit | 0.85 | PFLU_RS06310 | | sigma E protease regulator RseP | low | > 109 |
| Pseudomonas sp. DMC3 | 0.64 | GFF4213 | | Multidrug resistance protein MdtE | 0.87 | GFF2060 | | Regulator of sigma-E protease RseP | low | > 89 |
| Pseudomonas sp. RS175 | 0.64 | PFR28_04821 | | Multidrug resistance protein MdtE | 0.85 | PFR28_00403 | | Regulator of sigma-E protease RseP | low | > 88 |
| Pseudomonas fluorescens FW300-N1B4 | 0.63 | Pf1N1B4_1708 | | Efflux transporter, RND family, MFP subunit | 0.85 | Pf1N1B4_3091 | | Membrane-associated zinc metalloprotease | low | > 87 |
| Pseudomonas sp. SVBP6 | 0.62 | COO64_RS00860 | | efflux RND transporter periplasmic adaptor subunit | 0.80 | COO64_RS19675 | rseP | RIP metalloprotease RseP | low | > 93 |
| Pseudomonas fluorescens FW300-N2E2 | 0.62 | Pf6N2E2_3951 | | Efflux transporter, RND family, MFP subunit | 0.85 | Pf6N2E2_3062 | | Membrane-associated zinc metalloprotease | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.61 | AO356_10395 | | RND transporter | 0.85 | AO356_06005 | | zinc metallopeptidase RseP | low | > 104 |
| Pseudomonas sp. BP01 | 0.58 | JOY50_RS28380 | | efflux RND transporter periplasmic adaptor subunit | 0.83 | JOY50_RS26225 | rseP | RIP metalloprotease RseP | — | — |
| Pseudomonas putida KT2440 | 0.57 | PP_5175 | | HlyD family secretion protein | 0.83 | PP_1598 | | regulatory intramembrane protein RIP zinc protease | low | > 96 |
| Pseudomonas aeruginosa MRSN321 | 0.51 | DY961_RS27065 | triA;inference=COORDINATES | triclosan efflux RND transporter adaptor protein TriA | 0.79 | DY961_RS14730 | rseP;go_component=membrane|0016020||IEA;go_function=metalloendopeptidase | sigma E protease regulator RseP | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.51 | DQ20_RS31600 | triA;inference=COORDINATES | triclosan efflux RND transporter adaptor protein TriA | 0.79 | DQ20_RS42395 | rseP;go_component=membrane|0016020||IEA;go_function=metalloendopeptidase | sigma E protease regulator RseP | low | > 101 |
| Pseudomonas aeruginosa PA14 | 0.51 | IKLFDK_24760 | | triclosan efflux RND transporter adaptor protein TriA | 0.79 | IKLFDK_18630 | | metalloprotease protease | low | > 98 |
| Enterobacter asburiae PDN3 | 0.26 | EX28DRAFT_1519 | | RND family efflux transporter, MFP subunit | 0.45 | EX28DRAFT_3764 | | RIP metalloprotease RseP | — | — |
| Pseudomonas segetis P6 | 0.26 | MPMX49_01633 | | Multidrug resistance protein MdtA | 0.80 | MPMX49_03455 | | Regulator of sigma-E protease RseP | low | > 75 |
| Pantoea agglomerans CFBP13505 P0401 | 0.25 | PagCFBP13505_RS12055 | | efflux RND transporter periplasmic adaptor subunit | 0.44 | PagCFBP13505_RS13510 | | sigma E protease regulator RseP | — | — |
| Dechlorosoma suillum PS | 0.25 | Dsui_0409 | | RND family efflux transporter, MFP subunit | 0.37 | Dsui_2687 | | RIP metalloprotease RseP | low | > 51 |
| Klebsiella michiganensis M5al | 0.25 | BWI76_RS10855 | | RND family efflux transporter MFP subunit | 0.44 | BWI76_RS05250 | | zinc metallopeptidase RseP | — | — |
| Burkholderia phytofirmans PsJN | 0.25 | BPHYT_RS11370 | | RND transporter MFP subunit | 0.34 | BPHYT_RS12105 | | zinc metalloprotease | — | — |
| Dickeya dadantii 3937 | 0.24 | DDA3937_RS04725 | | efflux RND transporter periplasmic adaptor subunit | 0.43 | DDA3937_RS05150 | | sigma E protease regulator RseP | low | > 74 |
| Acinetobacter radioresistens SK82 | 0.24 | MPMX26_03011 | | Multidrug resistance protein MdtA | 0.40 | MPMX26_01300 | | Regulator of sigma-E protease RseP | low | > 36 |
| Acinetobacter baumannii LAC-4 | 0.24 | RR41_RS00165 | | efflux RND transporter periplasmic adaptor subunit | 0.39 | RR41_RS08070 | | RIP metalloprotease RseP | — | — |
| Pantoea sp. MT58 | 0.23 | IAI47_21720 | | efflux RND transporter periplasmic adaptor subunit | 0.44 | IAI47_15495 | | sigma E protease regulator RseP | — | — |
| Acidovorax sp. GW101-3H11 | 0.23 | Ac3H11_932 | | Probable Co/Zn/Cd efflux system membrane fusion protein | 0.29 | Ac3H11_425 | | Membrane-associated zinc metalloprotease | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.22 | H281DRAFT_05198 | | RND family efflux transporter, MFP subunit | 0.34 | H281DRAFT_00617 | | site-2 protease. Metallo peptidase. MEROPS family M50B | — | — |
| Methylophilus sp. DMC18 | 0.22 | GFF2821 | | Macrolide export protein MacA | 0.33 | GFF1006 | | Regulator of sigma-E protease RseP | — | — |
| Paraburkholderia graminis OAS925 | 0.21 | ABIE53_002353 | | multidrug efflux system membrane fusion protein | 0.32 | ABIE53_002496 | | regulator of sigma E protease | low | > 113 |
| Dyella japonica UNC79MFTsu3.2 | 0.21 | ABZR86_RS11130 | | efflux RND transporter periplasmic adaptor subunit | 0.35 | ABZR86_RS21620 | | RIP metalloprotease RseP | — | — |
| Herbaspirillum seropedicae SmR1 | 0.19 | HSERO_RS01320 | | RND transporter MFP subunit | 0.34 | HSERO_RS10910 | | peptidase | low | > 78 |
| Variovorax sp. SCN45 | 0.19 | GFF494 | | RND efflux system, membrane fusion protein | 0.32 | GFF386 | | Membrane-associated zinc metalloprotease | low | > 127 |
| Shewanella loihica PV-4 | 0.16 | Shew_0467 | | RND family efflux transporter MFP subunit (RefSeq) | 0.40 | Shew_2628 | | putative membrane-associated zinc metalloprotease (RefSeq) | — | — |
| Alteromonas macleodii MIT1002 | 0.13 | MIT1002_01562 | | Toluene efflux pump periplasmic linker protein TtgD precursor | 0.43 | MIT1002_01011 | | Regulator of sigma E protease | low | > 70 |
| Dinoroseobacter shibae DFL-12 | 0.11 | Dshi_3902 | | efflux transporter, RND family, MFP subunit (RefSeq) | 0.23 | Dshi_1498 | | putative membrane-associated zinc metalloprotease (RefSeq) | low | > 64 |
Not shown: 6 genomes with orthologs for Psyr_0344 only; 61 genomes with orthologs for Psyr_1350 only