Conservation of cofitness between HER17_RS10320 and HER17_RS06265 in Pectobacterium carotovorum WPP14

43 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS10320 flavin reductase 1.0 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.64 20
Serratia liquefaciens MT49 0.56 IAI46_09030 pyrimidine utilization flavin reductase protein F 0.85 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Enterobacter asburiae PDN3 0.54 EX28DRAFT_1919 pyrimidine utilization flavin reductase protein F 0.79 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Enterobacter sp. TBS_079 0.54 MPMX20_01694 FMN reductase (NADH) RutF 0.78 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 85
Escherichia coli ECRC98 0.53 JDDGAC_08250 rutF malonic semialdehyde reductase 0.78 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECOR38 0.53 HEPCGN_23500 rutF malonic semialdehyde reductase 0.78 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.53 OHPLBJKB_02659 FMN reductase (NADH) RutF 0.78 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia coli ECOR27 0.53 NOLOHH_21540 rutF malonic semialdehyde reductase 0.78 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Escherichia coli BL21 0.53 ECD_01010 flavin:NADH reductase 0.78 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase — —
Escherichia coli ECRC99 0.53 KEDOAH_23105 rutF malonic semialdehyde reductase 0.78 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC62 0.53 BNILDI_19705 rutF malonic semialdehyde reductase 0.78 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Escherichia fergusonii Becca 0.53 EFB2_03073 FMN reductase (NADH) RutF 0.78 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Escherichia coli BW25113 0.53 b1007 b1007 orf, hypothetical protein (VIMSS) 0.78 b2103 thiD phosphomethylpyrimidine kinase (NCBI) low > 76
Escherichia coli Nissle 1917 0.53 ECOLIN_RS26450 NADH-dependent FMN reductase RutF 0.77 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC100 0.53 OKFHMN_04640 rutF pyrimidine utilization flavin reductase protein F 0.78 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 80
Escherichia coli ECRC102 0.53 NIAGMN_23695 rutF pyrimidine utilization flavin reductase protein F 0.78 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC101 0.53 MCAODC_24025 rutF pyrimidine utilization flavin reductase protein F 0.78 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 87
Pantoea sp. MT58 0.52 IAI47_12530 pyrimidine utilization flavin reductase protein F 0.79 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_0995 Flavin reductase-like protein 0.24 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_0995 Flavin reductase-like protein 0.24 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Klebsiella michiganensis M5al 0.51 BWI76_RS10755 pyrimidine utilization flavin reductase protein F 0.78 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Agrobacterium fabrum C58 0.48 Atu2495 flavoprotein oxidoreductase 0.45 Atu3290 phosphomethylpyrimidine kinase low > 89
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS25005 FMN reductase 0.54 BPHYT_RS12250 phosphomethylpyrimidine kinase — —
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS07445 FMN reductase 0.19 HSERO_RS02135 phosphomethylpyrimidine kinase low > 78
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS07485 4-hydroxyphenylacetate 3-monooxygenase, reductase component 0.56 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_3748 4-hydroxyphenylacetate 3-monooxygenase, reductase component (EC 1.6.8.-) 0.23 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.36 GFF3275 4-hydroxyphenylacetate 3-monooxygenase, reductase component (EC 1.6.8.-) 0.78 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Paraburkholderia bryophila 376MFSha3.1 0.36 H281DRAFT_01660 4-hydroxyphenylacetate 3-monooxygenase reductase component (EC 1.14.13.3) 0.55 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase — —
Bosea sp. OAE506 0.34 ABIE41_RS13660 flavin reductase family protein 0.45 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia graminis OAS925 0.32 ABIE53_004540 flavin reductase (NADH) 0.51 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Rhizobium sp. OAE497 0.31 ABIE40_RS10095 flavin reductase 0.47 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Sinorhizobium meliloti 1021 0.29 SMc00514 monooxygenase 0.44 SM_b20962 phoshomethylpyrimidine kinase low > 103
Magnetospirillum magneticum AMB-1 0.27 AMB_RS12970 flavin reductase 0.31 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Rhodopseudomonas palustris CGA009 0.24 TX73_013510 flavin reductase family protein 0.44 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pseudomonas sp. RS175 0.24 PFR28_02021 FMN reductase (NADH) RutF 0.22 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 88
Cupriavidus basilensis FW507-4G11 0.23 RR42_RS31995 flavin reductase 0.31 RR42_RS01370 phosphomethylpyrimidine kinase — —
Caulobacter crescentus NA1000 Δfur 0.21 CCNA_02358 FMN reductase 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Caulobacter crescentus NA1000 0.21 CCNA_02358 FMN reductase 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Pseudomonas simiae WCS417 0.21 PS417_17920 nitrilotriacetate monooxygenase 0.25 PS417_24600 hydrogenase low > 88
Azospirillum brasilense Sp245 0.21 AZOBR_RS20045 flavin reductase 0.35 AZOBR_RS07045 phosphomethylpyrimidine kinase — —
Rhodospirillum rubrum S1H 0.20 Rru_A1841 Flavin reductase-like, FMN-binding (NCBI) 0.37 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) — —
Castellaniella sp019104865 MT123 0.20 ABCV34_RS06740 flavin reductase family protein 0.44 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Dechlorosoma suillum PS 0.19 Dsui_1004 conserved protein of DIM6/NTAB family 0.23 Dsui_0662 phosphomethylpyrimidine kinase — —
Acidovorax sp. GW101-3H11 0.16 Ac3H11_4854 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) 0.34 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —

Not shown: 2 genomes with orthologs for HER17_RS10320 only; 48 genomes with orthologs for HER17_RS06265 only