Conservation of cofitness between HER17_RS01300 and HER17_RS02600 in Pectobacterium carotovorum WPP14

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS01300 protoheme IX biogenesis protein HemY 1.0 HER17_RS02600 protease modulator HflC 0.72 18
Serratia liquefaciens MT49 0.79 IAI46_00680 protoheme IX biogenesis protein HemY 0.81 IAI46_01640 protease modulator HflC low > 86
Dickeya dadantii 3937 0.76 DDA3937_RS19935 protoheme IX biogenesis protein HemY 0.82 DDA3937_RS18595 protease modulator HflC
Rahnella sp. WP5 0.75 EX31_RS15130 protoheme IX biogenesis protein HemY 0.77 EX31_RS08805 protease modulator HflC low > 89
Dickeya dianthicola ME23 0.74 DZA65_RS21135 protoheme IX biogenesis protein HemY 0.82 DZA65_RS19665 protease modulator HflC low > 75
Dickeya dianthicola 67-19 0.74 HGI48_RS20090 protoheme IX biogenesis protein HemY 0.82 HGI48_RS18530 protease modulator HflC low > 71
Erwinia tracheiphila SCR3 0.73 LU632_RS24175 hemY protoheme IX biogenesis protein HemY 0.79 LU632_RS02070 hflC protease modulator HflC low > 74
Escherichia coli ECRC101 0.73 MCAODC_04970 hemY protoheme IX biogenesis protein HemY 0.77 MCAODC_02755 hflC protease modulator HflC low > 87
Escherichia coli BW25113 0.73 b3802 hemY predicted protoheme IX synthesis protein (NCBI) 0.77 b4175 hflC modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli ECOR27 0.73 NOLOHH_06610 hemY protoheme IX biogenesis protein HemY 0.77 NOLOHH_04505 hflC protease modulator HflC low > 75
Escherichia coli ECRC102 0.73 NIAGMN_12220 hemY protoheme IX biogenesis protein HemY 0.77 NIAGMN_10090 hflC protease modulator HflC
Escherichia coli ECRC100 0.73 OKFHMN_14465 hemY protoheme IX biogenesis protein HemY 0.77 OKFHMN_12240 hflC protease modulator HflC low > 80
Escherichia coli Nissle 1917 0.73 ECOLIN_RS21820 protoheme IX biogenesis protein HemY 0.77 ECOLIN_RS24245 protease modulator HflC
Escherichia coli ECRC99 0.73 KEDOAH_13685 hemY protoheme IX biogenesis protein HemY 0.77 KEDOAH_15915 hflC protease modulator HflC
Escherichia coli BL21 0.73 ECD_03677 putative protoheme IX synthesis protein 0.77 ECD_04042 HflB protease modulator specific for phage lambda cII repressor low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_04251 Protein HemY 0.77 OHPLBJKB_03867 Modulator of FtsH protease HflC 0.67 63
Escherichia coli ECOR38 0.73 HEPCGN_13185 hemY protoheme IX biogenesis protein HemY 0.77 HEPCGN_10470 hflC protease modulator HflC low > 87
Escherichia coli ECRC62 0.73 BNILDI_04925 hemY protoheme IX biogenesis protein HemY 0.77 BNILDI_06985 hflC protease modulator HflC low > 75
Escherichia fergusonii Becca 0.73 EFB2_04836 Protein HemY 0.77 EFB2_04360 Modulator of FtsH protease HflC low > 86
Escherichia coli ECRC98 0.73 JDDGAC_18090 hemY protoheme IX biogenesis protein HemY 0.77 JDDGAC_15880 hflC protease modulator HflC low > 86
Enterobacter sp. TBS_079 0.71 MPMX20_04473 Protein HemY 0.74 MPMX20_00456 Modulator of FtsH protease HflC 0.34 57
Enterobacter asburiae PDN3 0.71 EX28DRAFT_4471 heme biosynthesis-associated TPR protein 0.73 EX28DRAFT_3372 HflC protein low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.69 GFF226 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.77 GFF828 HflC protein low > 78
Klebsiella michiganensis M5al 0.69 BWI76_RS01165 protoheme IX biogenesis protein HemY 0.75 BWI76_RS02550 protease modulator HflC low > 92
Pantoea sp. MT58 0.68 IAI47_18440 protoheme IX biogenesis protein HemY 0.77 IAI47_02605 protease modulator HflC low > 76
Vibrio cholerae E7946 ATCC 55056 0.25 CSW01_00595 heme biosynthesis protein HemY 0.49 CSW01_01850 protease modulator HflC low > 62
Kangiella aquimarina DSM 16071 0.18 B158DRAFT_0255 Uncharacterized enzyme of heme biosynthesis 0.34 B158DRAFT_1955 HflC protein 0.82 6
Pseudomonas stutzeri RCH2 0.16 Psest_3745 Uncharacterized enzyme of heme biosynthesis 0.29 Psest_0686 Membrane protease subunits, stomatin/prohibitin homologs
Marinobacter adhaerens HP15 0.15 HP15_237 HemY domain protein 0.31 HP15_2496 HflC low > 73
Pseudomonas fluorescens FW300-N2E2 0.15 Pf6N2E2_4433 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.31 Pf6N2E2_3611 HflC protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.14 AO356_12800 heme biosynthesis protein HemY 0.31 AO356_08640 membrane protease HflC 0.28 59
Pseudomonas fluorescens FW300-N2E3 0.13 AO353_08975 heme biosynthesis protein HemY 0.31 AO353_13160 membrane protease HflC low > 101
Pseudomonas fluorescens GW456-L13 0.13 PfGW456L13_859 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.31 PfGW456L13_151 HflC protein low > 87
Pseudomonas simiae WCS417 0.13 PS417_27515 heme biosynthesis protein HemY 0.29 PS417_02505 membane protease HflC
Alteromonas macleodii MIT1002 0.13 MIT1002_00099 putative protoheme IX biogenesis protein 0.48 MIT1002_03785 Modulator of FtsH protease HflC 0.77 40
Pseudomonas fluorescens FW300-N1B4 0.13 Pf1N1B4_2188 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.31 Pf1N1B4_1409 HflC protein
Pseudomonas fluorescens SBW25-INTG 0.12 PFLU_RS29195 heme biosynthesis protein HemY 0.31 PFLU_RS02585 protease modulator HflC low > 109
Shewanella sp. ANA-3 0.12 Shewana3_0383 HemY domain-containing protein (RefSeq) 0.48 Shewana3_0600 HflC protein (RefSeq) low > 73
Shewanella loihica PV-4 0.12 Shew_0315 HemY domain-containing protein (RefSeq) 0.46 Shew_0569 HflC protein (RefSeq) low > 60
Pseudomonas fluorescens SBW25 0.12 PFLU_RS29195 heme biosynthesis protein HemY 0.31 PFLU_RS02585 protease modulator HflC 0.62 11
Pseudomonas sp. RS175 0.12 PFR28_04363 Protein HemY 0.28 PFR28_05124 Modulator of FtsH protease HflC low > 88
Pseudomonas putida KT2440 0.12 PP_0189 putative heme biosynthesis protein 0.29 PP_4891 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex low > 96
Pseudomonas sp. S08-1 0.12 OH686_13915 Uncharacterized protein EC-HemY in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.29 OH686_09455 HflC protein low > 80
Pseudomonas syringae pv. syringae B728a 0.12 Psyr_0059 HemY, N-terminal:HemY, N-terminal:HemY, N-terminal 0.31 Psyr_0575 protease FtsH subunit HflC low > 86
Shewanella amazonensis SB2B 0.12 Sama_3257 HemY protein (RefSeq) 0.45 Sama_3022 hflC protein (RefSeq) low > 62
Pseudomonas syringae pv. syringae B728a ΔmexB 0.12 Psyr_0059 HemY, N-terminal:HemY, N-terminal:HemY, N-terminal 0.31 Psyr_0575 protease FtsH subunit HflC 0.55 32
Herbaspirillum seropedicae SmR1 0.08 HSERO_RS14650 porphyrin biosynthesis protein 0.27 HSERO_RS14760 membrane protein

Not shown: 0 genomes with orthologs for HER17_RS01300 only; 38 genomes with orthologs for HER17_RS02600 only