| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_16820 | | PTS fructose transporter subunit IIBC | 1.0 | CSW01_12340 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase | 0.44 | 17 |
| Pseudomonas fluorescens GW456-L13 | 0.61 | PfGW456L13_5073 | | PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) | 0.57 | PfGW456L13_195 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.60 | AO353_05475 | | PTS fructose transporter subunit IIBC | 0.57 | AO353_12970 | | heptose 1-phosphate adenyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.60 | Pf6N2E2_3337 | | PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) | 0.57 | Pf6N2E2_3653 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | — | — |
| Pseudomonas sp. RS175 | 0.60 | PFR28_00107 | | hypothetical protein | 0.57 | PFR28_05083 | | Bifunctional protein HldE | — | — |
| Pseudomonas sp. DMC3 | 0.60 | GFF5005 | | PTS system fructose-specific EIIB'BC component | 0.57 | GFF3175 | | Bifunctional protein HldE | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.59 | Psyr_0823 | | PTS system D-fructose-specific IIB component (F1P-forming), Frc family / PTS system D-fructose-specific IIC component (F1P-forming), Frc family | 0.57 | Psyr_0537 | | D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.59 | Psyr_0823 | | PTS system D-fructose-specific IIB component (F1P-forming), Frc family / PTS system D-fructose-specific IIC component (F1P-forming), Frc family | 0.57 | Psyr_0537 | | D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.59 | Pf1N1B4_1144 | | PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) | 0.57 | Pf1N1B4_1455 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | — | — |
| Pantoea sp. MT58 | 0.59 | IAI47_06660 | | PTS fructose transporter subunit IIBC | 0.67 | IAI47_03105 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas sp. SVBP6 | 0.59 | COO64_RS11285 | | PTS fructose-like transporter subunit IIB | 0.57 | COO64_RS17715 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pantoea agglomerans CFBP13505 P0401 | 0.58 | PagCFBP13505_RS00755 | | PTS fructose transporter subunit IIBC | 0.67 | PagCFBP13505_RS11925 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.58 | AO356_07325 | | fructose phosphotransferase system, IIB/IIC components (EC 2.7.1.202) (from data) | 0.57 | AO356_08850 | | heptose 1-phosphate adenyltransferase | — | — |
| Pseudomonas lactucae CFBP13502 | 0.58 | GEMAOFIL_00999 | | 'PTS system fructose-specific EIIB'BC component' transl_table=11 | 0.58 | GEMAOFIL_00699 | | Bifunctional protein HldE | — | — |
| Serratia liquefaciens MT49 | 0.58 | IAI46_17230 | | PTS fructose transporter subunit IIBC | 0.70 | IAI46_22055 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Erwinia tracheiphila SCR3 | 0.58 | LU632_RS17315 | fruA | PTS fructose transporter subunit IIBC | 0.69 | LU632_RS20670 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Erwinia tracheiphila HP pepo 2.2 | 0.58 | IJEDHG_25890 | fruA | PTS fructose transporter subunit IIBC | 0.69 | IJEDHG_14390 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas stutzeri RCH2 | 0.58 | Psest_3353 | | PTS system, fructose-specific, IIB component/PTS system, fructose subfamily, IIC component | 0.59 | Psest_0470 | | rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II | — | — |
| Rahnella sp. WP5 | 0.57 | EX31_RS19065 | | PTS fructose transporter subunit IIBC | 0.69 | EX31_RS08140 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | low | > 89 |
| Pseudomonas fluorescens SBW25-INTG | 0.57 | PFLU_RS04020 | | PTS fructose-like transporter subunit IIB | 0.58 | PFLU_RS02385 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas fluorescens SBW25 | 0.57 | PFLU_RS04020 | | PTS fructose-like transporter subunit IIB | 0.58 | PFLU_RS02385 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas sp. BP01 | 0.57 | JOY50_RS19305 | | PTS fructose-like transporter subunit IIB | 0.58 | JOY50_RS10025 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli BL21 | 0.57 | ECD_02096 | | fused fructose-specific PTS enzymes: IIBcomponent/IIC components | 0.69 | ECD_02922 | | heptose 7-phosphate kinase and heptose 1-phosphate adenyltransferase | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.57 | OHPLBJKB_01543 | | 'PTS system fructose-specific EIIB'BC component' transl_table=11 | 0.69 | OHPLBJKB_00652 | | Bifunctional protein HldE | — | — |
| Pectobacterium carotovorum WPP14 | 0.57 | HER17_RS12855 | | PTS fructose transporter subunit IIBC | 0.70 | HER17_RS04040 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECOR27 | 0.57 | NOLOHH_15020 | fruA | PTS fructose transporter subunit IIBC | 0.69 | NOLOHH_10520 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC62 | 0.57 | BNILDI_13940 | fruA | PTS fructose transporter subunit IIBC | 0.69 | BNILDI_00995 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas simiae WCS417 | 0.56 | PS417_03975 | | FruA | 0.58 | PS417_02310 | | heptose 1-phosphate adenyltransferase | — | — |
| Dickeya dianthicola ME23 | 0.56 | DZA65_RS09575 | | PTS fructose transporter subunit IIBC | 0.68 | DZA65_RS18235 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli BW25113 | 0.56 | b2167 | fruA | fused fructose-specific PTS enzymes: IIBcomponent/IIC components (NCBI) | 0.69 | b3052 | rfaE | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | low | > 76 |
| Escherichia coli ECOR38 | 0.56 | HEPCGN_22710 | fruA | PTS fructose transporter subunit IIBC | 0.69 | HEPCGN_17590 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC100 | 0.56 | OKFHMN_23445 | fruA | PTS fructose transporter subunit IIBC | 0.69 | OKFHMN_18735 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC102 | 0.56 | NIAGMN_21210 | fruA | PTS fructose transporter subunit IIBC | 0.69 | NIAGMN_16500 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC101 | 0.56 | MCAODC_14495 | fruA | PTS fructose transporter subunit IIBC | 0.69 | MCAODC_09250 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC99 | 0.56 | KEDOAH_04740 | fruA | PTS fructose transporter subunit IIBC | 0.69 | KEDOAH_09410 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC98 | 0.56 | JDDGAC_27405 | fruA | PTS fructose transporter subunit IIBC | 0.69 | JDDGAC_22370 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia fergusonii Becca | 0.56 | EFB2_01690 | | PTS system fructose-specific EIIB'BC component | 0.69 | EFB2_00759 | | Bifunctional protein HldE | — | — |
| Dickeya dianthicola 67-19 | 0.56 | HGI48_RS09270 | | PTS fructose transporter subunit IIBC | 0.68 | HGI48_RS17150 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli Nissle 1917 | 0.56 | ECOLIN_RS12675 | | PTS fructose transporter subunit IIBC | 0.69 | ECOLIN_RS17615 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Enterobacter sp. TBS_079 | 0.56 | MPMX20_03131 | | PTS system fructose-specific EIIB'BC component | 0.69 | MPMX20_03889 | | Bifunctional protein HldE | — | — |
| Enterobacter asburiae PDN3 | 0.56 | EX28DRAFT_0396 | | PTS system, fructose-specific, IIB component/PTS system, fructose subfamily, IIC component | 0.68 | EX28DRAFT_3080 | | rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.56 | GFF3773 | | PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) | 0.69 | GFF3166 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | low | > 78 |
| Dickeya dadantii 3937 | 0.56 | DDA3937_RS09240 | | PTS fructose transporter subunit IIBC | 0.68 | DDA3937_RS17100 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Erwinia amylovora T8 | 0.55 | OLJFJH_11780 | | PTS fructose transporter subunit IIBC | 0.65 | OLJFJH_07645 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas putida KT2440 | 0.55 | PP_0795 | | fructose PTS permease - IIBC component | 0.56 | PP_4934 | | heptose 7-phosphate kinase/heptose 1-phosphate adenylyltransferase | — | — |
| Klebsiella michiganensis M5al | 0.55 | BWI76_RS19725 | | PTS fructose transporter subunit EIIBC | 0.68 | BWI76_RS24455 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase | — | — |
| Klebsiella pneumoniae MKP103 | 0.53 | KDGMDA_26660 | | PTS fructose transporter subunit IIBC | 0.68 | KDGMDA_05265 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas aeruginosa PA14 | 0.51 | IKLFDK_18170 | | PTS fructose-like transporter subunit IIB | 0.58 | IKLFDK_28555 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Rhodospirillum rubrum S1H | 0.43 | Rru_A1970 | | PTS fructose IIC component (NCBI) | 0.34 | Rru_A0123 | | RfaE-HldE bifunctional protein, D-beta-D-heptose 7-phosphate kinase, D-beta-D-heptose 1-phosphate adenosyltransferase (NCBI) | — | — |
| Azospirillum brasilense Sp245 | 0.42 | AZOBR_RS32335 | | fructose-specific PTS system (fructose 1-phosphate forming), EII-B'BC components (FruA) (from data) | 0.37 | AZOBR_RS33905 | | D-beta-D-heptose 1-phosphate adenosyltransferase | low | > 97 |
| Azospirillum sp. SherDot2 | 0.41 | MPMX19_05329 | | PTS system fructose-specific EIIB'BC component | 0.36 | MPMX19_02117 | | Bifunctional protein HldE | — | — |
Not shown: 9 genomes with orthologs for CSW01_16820 only; 14 genomes with orthologs for CSW01_12340 only