| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_18785 | | DUF808 domain-containing protein | 1.0 | CSW01_07060 | | TetR/AcrR family transcriptional regulator | 0.50 | 7 |
| Pseudomonas fluorescens FW300-N2E3 | 0.58 | AO353_01900 | | hypothetical protein | 0.19 | AO353_16355 | | TetR family transcriptional regulator | low | > 101 |
| Pseudomonas aeruginosa PUPa3 | 0.57 | DQ20_RS55100 | | DUF808 domain-containing protein | 0.20 | DQ20_RS42755 | nalC;inference=COORDINATES | efflux system transcriptional repressor NalC | low | > 101 |
| Pseudomonas aeruginosa PA14 | 0.56 | IKLFDK_09045 | | DUF808 domain-containing protein | 0.20 | IKLFDK_18995 | | efflux system transcriptional repressor NalC | low | > 98 |
| Acinetobacter baumannii LAC-4 | 0.56 | RR41_RS04085 | | DUF808 domain-containing protein | 0.18 | RR41_RS13370 | | TetR/AcrR family transcriptional regulator | low | > 55 |
| Pseudomonas aeruginosa MRSN321 | 0.55 | DY961_RS21030 | | DUF808 domain-containing protein | 0.20 | DY961_RS14370 | nalC;inference=COORDINATES | efflux system transcriptional repressor NalC | low | > 100 |
| Pseudomonas orientalis W4I3 | 0.55 | QF045_RS11525 | | DUF808 domain-containing protein | 0.20 | QF045_RS08955 | | TetR/AcrR family transcriptional regulator | low | > 93 |
| Pseudomonas fluorescens FW300-N1B4 | 0.55 | Pf1N1B4_3666 | | Membrane protein, putative | 0.18 | Pf1N1B4_3061 | | Transcriptional regulator, TetR family | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.54 | PfGW456L13_4283 | | Membrane protein, putative | 0.20 | PfGW456L13_4732 | | Transcriptional regulator, TetR family | 0.22 | 78 |
| Pseudomonas sp. S08-1 | 0.54 | OH686_13580 | | Inner membrane protein YedI | 0.21 | OH686_06750 | | Transcriptional regulator, AcrR family | low | > 80 |
| Pseudomonas fluorescens FW300-N2C3 | 0.54 | AO356_19640 | | hypothetical protein | 0.20 | AO356_06140 | | TetR family transcriptional regulator | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.54 | Pf6N2E2_5844 | | Membrane protein, putative | 0.19 | Pf6N2E2_3093 | | Transcriptional regulator, TetR family | low | > 103 |
| Acidovorax sp. GW101-3H11 | 0.53 | Ac3H11_540 | | Membrane protein, putative | 0.20 | Ac3H11_620 | | Transcriptional regulator, TetR family | low | > 79 |
| Shewanella amazonensis SB2B | 0.53 | Sama_2735 | | hypothetical protein (RefSeq) | 0.19 | Sama_2341 | | TetR family transcriptional regulator (RefSeq) | low | > 62 |
| Acinetobacter radioresistens SK82 | 0.53 | MPMX26_00757 | | Inner membrane protein YedI | 0.16 | MPMX26_03012 | | hypothetical protein | low | > 36 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.53 | Psyr_1803 | | Protein of unknown function DUF808 | 0.31 | Psyr_3347 | | transcriptional regulator, TetR family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.53 | Psyr_1803 | | Protein of unknown function DUF808 | 0.31 | Psyr_3347 | | transcriptional regulator, TetR family | — | — |
| Shewanella loihica PV-4 | 0.52 | Shew_0826 | | hypothetical protein (RefSeq) | 0.18 | Shew_1544 | | TetR family transcriptional regulator (RefSeq) | low | > 60 |
| Enterobacter asburiae PDN3 | 0.52 | EX28DRAFT_0596 | | Uncharacterized protein conserved in bacteria | 0.27 | EX28DRAFT_2612 | | transcriptional regulator, TetR family | — | — |
| Pseudomonas stutzeri RCH2 | 0.52 | Psest_1878 | | Uncharacterized protein conserved in bacteria | 0.20 | Psest_1564 | | Transcriptional regulator | — | — |
| Pseudomonas sp. BP01 | 0.52 | JOY50_RS00335 | | DUF808 domain-containing protein | 0.18 | JOY50_RS26080 | | TetR/AcrR family transcriptional regulator | low | > 84 |
| Pseudomonas putida KT2440 | 0.51 | PP_4294 | | conserved inner membrane protein | 0.19 | PP_1515 | | Transcriptional regulator, tetR family | low | > 96 |
| Erwinia amylovora T8 | 0.50 | OLJFJH_12500 | | DUF808 domain-containing protein | 0.32 | OLJFJH_14170 | | TetR family transcriptional regulator | low | > 58 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.49 | Xcc-8004.533.1 | | Membrane protein, putative | 0.32 | Xcc-8004.1792.1 | | Transcription regulator of multidrug efflux pump operon, TetR (AcrR) family | low | > 74 |
| Rahnella sp. WP5 | 0.49 | EX31_RS21945 | | DUF808 domain-containing protein | 0.29 | EX31_RS00510 | | TetR/AcrR family transcriptional regulator | low | > 89 |
| Klebsiella pneumoniae MKP103 | 0.49 | KDGMDA_25670 | | DUF808 domain-containing protein | 0.20 | KDGMDA_24185 | | TetR/AcrR family transcriptional regulator | low | > 95 |
| Herbaspirillum seropedicae SmR1 | 0.47 | HSERO_RS02085 | | membrane protein | 0.42 | HSERO_RS16340 | | transcriptional regulator | low | > 78 |
| Alteromonas macleodii MIT1002 | 0.44 | MIT1002_00412 | | Inner membrane protein YedI | 0.17 | MIT1002_00424 | | Solvent efflux pump srpABC operon corepressor | low | > 70 |
| Phaeobacter inhibens DSM 17395 | 0.32 | PGA1_c17240 | | Uncharacterized protein conserved in bacteria | 0.21 | PGA1_c31580 | | putative HTH-type transcriptional regulator, TetR family | low | > 62 |
| Bosea sp. OAE506 | 0.30 | ABIE41_RS07790 | | DUF808 domain-containing protein | 0.26 | ABIE41_RS08455 | | TetR/AcrR family transcriptional regulator | low | > 77 |
| Sphingomonas koreensis DSMZ 15582 | 0.28 | Ga0059261_0099 | | Uncharacterized protein conserved in bacteria | 0.17 | Ga0059261_3939 | | transcriptional regulator, TetR family | low | > 68 |
| Sphingobium sp. HT1-2 | 0.27 | GFF1564 | | putative membrane protein | 0.25 | GFF3798 | | Transcriptional regulator, AcrR family | 0.67 | 24 |
| Dinoroseobacter shibae DFL-12 | 0.27 | Dshi_1739 | | protein of unknown function DUF808 (RefSeq) | 0.19 | Dshi_0106 | | transcriptional regulator, TetR family (RefSeq) | low | > 64 |
Not shown: 40 genomes with orthologs for CSW01_18785 only; 21 genomes with orthologs for CSW01_07060 only