| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_13560 | | methylenetetrahydrofolate reductase | 1.0 | CSW01_02830 | | murein hydrolase activator NlpD | 0.67 | 11 |
| Rahnella sp. WP5 | 0.78 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.41 | EX31_RS07830 | | murein hydrolase activator NlpD | low | > 89 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.77 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.39 | GFF4789 | | Lipoprotein NlpD | low | > 78 |
| Serratia liquefaciens MT49 | 0.76 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.38 | IAI46_03785 | | murein hydrolase activator NlpD | low | > 87 |
| Shewanella amazonensis SB2B | 0.76 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.33 | Sama_1043 | | lipoprotein NlpD (RefSeq) | low | > 62 |
| Shewanella loihica PV-4 | 0.74 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.35 | Shew_1212 | | peptidase M23B (RefSeq) | low | > 60 |
| Shewanella sp. ANA-3 | 0.73 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.36 | Shewana3_1123 | | peptidase M23B (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.73 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.34 | SO3433 | nlpD | lipoprotein NlpD (NCBI ptt file) | low | > 76 |
| Alteromonas macleodii MIT1002 | 0.66 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | 0.37 | MIT1002_00626 | | Murein hydrolase activator NlpD precursor | low | > 70 |
| Kangiella aquimarina DSM 16071 | 0.57 | B158DRAFT_2461 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) | 0.29 | B158DRAFT_2299 | | Membrane proteins related to metalloendopeptidases | low | > 40 |
| Cupriavidus basilensis FW507-4G11 | 0.35 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | 0.22 | RR42_RS13190 | | outer membrane metallopeptidase lipoprotein nlpD | low | > 128 |
| Pseudomonas putida KT2440 | 0.35 | PP_4977 | | 5,10-methylenetetrahydrofolate reductase | 0.28 | PP_1622 | | metallopeptidase, M23B subfamily | — | — |
| Pseudomonas sp. BP01 | 0.35 | JOY50_RS09810 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | JOY50_RS23750 | | peptidoglycan DD-metalloendopeptidase family protein | — | — |
| Dechlorosoma suillum PS | 0.35 | Dsui_0640 | | 5,10-methylenetetrahydrofolate reductase | 0.30 | Dsui_1970 | | metalloendopeptidase-like membrane protein | — | — |
| Pseudomonas sp. DMC3 | 0.35 | GFF171 | | 5,10-methylenetetrahydrofolate reductase | 0.29 | GFF2083 | | Murein hydrolase activator NlpD | — | — |
| Pseudomonas sp. S08-1 | 0.35 | OH686_10820 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | OH686_18180 | | Murein hydrolase activator NlpD | low | > 80 |
| Pseudomonas fluorescens FW300-N2E3 | 0.34 | AO353_08015 | | 5,10-methylenetetrahydrofolate reductase | 0.29 | AO353_16610 | | peptigoglycan-binding protein LysM | — | — |
| Pseudomonas fluorescens SBW25 | 0.34 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | PFLU_RS06425 | | peptidoglycan DD-metalloendopeptidase family protein | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.34 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | PFLU_RS06425 | | peptidoglycan DD-metalloendopeptidase family protein | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.34 | DY961_RS22135 | metF;go_function=methylenetetrahydrofolate | methylenetetrahydrofolate reductase [NAD(P)H] | 0.30 | DY961_RS14860 | | peptidoglycan DD-metalloendopeptidase family protein | low | > 100 |
| Pseudomonas sp. SVBP6 | 0.34 | COO64_RS17485 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.30 | COO64_RS19790 | | peptidoglycan DD-metalloendopeptidase family protein | low | > 93 |
| Pseudomonas aeruginosa PUPa3 | 0.34 | DQ20_RS37170 | metF;go_function=methylenetetrahydrofolate | methylenetetrahydrofolate reductase [NAD(P)H] | 0.30 | DQ20_RS42265 | | peptidoglycan DD-metalloendopeptidase family protein | low | > 101 |
| Pseudomonas aeruginosa PA14 | 0.34 | IKLFDK_23270 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.30 | IKLFDK_18500 | | Lipo NlpD/LppB-like protein | low | > 98 |
| Dyella japonica UNC79MFTsu3.2 | 0.34 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.21 | ABZR86_RS06580 | | peptidoglycan DD-metalloendopeptidase family protein | low | > 74 |
| Pseudomonas lactucae CFBP13502 | 0.34 | GEMAOFIL_05433 | | 5,10-methylenetetrahydrofolate reductase | 0.29 | GEMAOFIL_01442 | | hypothetical protein | — | — |
| Castellaniella sp019104865 MT123 | 0.34 | ABCV34_RS13550 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.22 | ABCV34_RS03040 | | peptidoglycan DD-metalloendopeptidase family protein | — | — |
| Rhodanobacter denitrificans MT42 | 0.34 | LRK55_RS11765 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.21 | LRK55_RS16390 | | peptidoglycan DD-metalloendopeptidase family protein | — | — |
| Methylophilus sp. DMC18 | 0.34 | GFF1492 | | 5,10-methylenetetrahydrofolate reductase | 0.20 | GFF448 | | Murein hydrolase activator NlpD | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.34 | LRK54_RS12030 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.21 | LRK54_RS16665 | | peptidoglycan DD-metalloendopeptidase family protein | low | > 59 |
| Rhodanobacter sp. FW510-T8 | 0.33 | OKGIIK_11830 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.21 | OKGIIK_08100 | | Peptidase M23 | low | > 53 |
| Acidovorax sp. GW101-3H11 | 0.33 | Ac3H11_3045 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.23 | Ac3H11_1786 | | Lipoprotein NlpD | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.33 | LRK53_RS16505 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.20 | LRK53_RS12255 | | peptidoglycan DD-metalloendopeptidase family protein | — | — |
| Herbaspirillum seropedicae SmR1 | 0.32 | HSERO_RS21425 | | 5,10-methylenetetrahydrofolate reductase | 0.27 | HSERO_RS14835 | | peptidase M23 | low | > 78 |
| Acinetobacter baumannii LAC-4 | 0.32 | RR41_RS05725 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.20 | RR41_RS05350 | | peptidoglycan DD-metalloendopeptidase family protein | low | > 55 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.31 | GFF1692 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.24 | GFF3881 | | Lipoprotein NlpD | — | — |
| Variovorax sp. OAS795 | 0.31 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.27 | ABID97_RS10725 | | peptidoglycan DD-metalloendopeptidase family protein | low | > 91 |
| Variovorax sp. SCN45 | 0.31 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.27 | GFF2843 | | Murein hydrolase activator NlpD | 0.89 | 31 |
Not shown: 82 genomes with orthologs for CSW01_13560 only; 0 genomes with orthologs for CSW01_02830 only