Conservation of cofitness between CSW01_17220 and CSW01_02060 in Vibrio cholerae E7946 ATCC 55056

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_17220 phosphonate utilization transcriptional regulator PhnR 1.0 CSW01_02060 methionine synthase 0.55 9
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_02400 MFS transporter 0.64 AO353_21615 methionine synthase low > 101
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_19385 MFS transporter 0.64 AO356_00545 methionine synthase low > 104
Pseudomonas sp. DMC3 0.47 GFF2592 Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons 0.65 GFF3687 Methionine synthase low > 89
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_3749 2-aminoethylphosphonate uptake and metabolism regulator 0.64 Pf1N1B4_5661 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 87
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_5791 2-aminoethylphosphonate uptake and metabolism regulator 0.64 Pf6N2E2_2068 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 103
Pseudomonas fluorescens GW456-L13 0.46 PfGW456L13_4198 2-aminoethylphosphonate uptake and metabolism regulator 0.64 PfGW456L13_2847 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 87
Pseudomonas segetis P6 0.46 MPMX49_01786 Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons 0.65 MPMX49_02589 Methionine synthase low > 75
Pseudomonas sp. SVBP6 0.46 COO64_RS06940 phnR phosphonate utilization transcriptional regulator PhnR 0.64 COO64_RS24910 metH methionine synthase low > 93
Pseudomonas sp. RS175 0.46 PFR28_03159 Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons 0.64 PFR28_01369 Methionine synthase low > 88
Pseudomonas putida KT2440 0.45 PP_1727 Transcriptional regulator, GntR family 0.65 PP_2375 cobalamin-dependent methionine synthase low > 96
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS10020 UTRA domain-containing protein 0.65 PFLU_RS13000 methionine synthase low > 109
Pseudomonas syringae pv. syringae B728a 0.45 Psyr_1607 transcriptional regulator, GntR family 0.64 Psyr_2464 methionine synthase (B12-dependent) low > 86
Pseudomonas sp. BP01 0.45 JOY50_RS27920 UTRA domain-containing protein 0.65 JOY50_RS10720 metH methionine synthase low > 84
Pseudomonas syringae pv. syringae B728a ΔmexB 0.45 Psyr_1607 transcriptional regulator, GntR family 0.64 Psyr_2464 methionine synthase (B12-dependent) low > 86
Pseudomonas fluorescens SBW25 0.45 PFLU_RS10020 UTRA domain-containing protein 0.65 PFLU_RS13000 methionine synthase low > 109
Pseudomonas sp. S08-1 0.44 OH686_19750 Transcriptional regulator, GntR family 0.65 OH686_03335 methionine synthase low > 80
Pseudomonas aeruginosa MRSN321 0.44 DY961_RS00670 UTRA domain-containing protein 0.66 DY961_RS20955 metH;go_function=zinc methionine synthase low > 100
Pseudomonas aeruginosa PA14 0.44 IKLFDK_16615 MFS transporter 0.66 IKLFDK_08975 methionine synthase low > 98
Pseudomonas simiae WCS417 0.44 PS417_09365 MFS transporter 0.64 PS417_12310 methionine synthase low > 88
Pseudomonas aeruginosa PUPa3 0.44 DQ20_RS40365 UTRA domain-containing protein 0.66 DQ20_RS55030 metH;go_function=zinc methionine synthase low > 101
Pseudomonas lactucae CFBP13502 0.44 GEMAOFIL_02105 Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons 0.64 GEMAOFIL_02709 Methionine synthase low > 96
Pantoea sp. MT58 0.43 IAI47_17920 UTRA domain-containing protein 0.75 IAI47_17990 methionine synthase low > 76
Klebsiella pneumoniae MKP103 0.43 KDGMDA_08455 phosphonate utilization transcriptional regulator PhnR 0.76 KDGMDA_10165 methionine synthase low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.43 GFF4332 2-aminoethylphosphonate uptake and metabolism regulator 0.76 GFF1358 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 78
Rahnella sp. WP5 0.42 EX31_RS11765 UTRA domain-containing protein 0.75 EX31_RS11760 methionine synthase low > 89
Pantoea agglomerans CFBP13505 P0401 0.42 PagCFBP13505_RS22230 UTRA domain-containing protein 0.76 PagCFBP13505_RS22305 methionine synthase low > 74
Serratia liquefaciens MT49 0.42 IAI46_10825 phosphonate utilization transcriptional regulator PhnR 0.75 IAI46_23155 methionine synthase low > 87
Dickeya dadantii 3937 0.37 DDA3937_RS17460 UTRA domain-containing protein 0.76 DDA3937_RS19040 methionine synthase low > 74
Dickeya dianthicola 67-19 0.37 HGI48_RS17525 UTRA domain-containing protein 0.75 HGI48_RS19130 methionine synthase low > 71
Dickeya dianthicola ME23 0.37 DZA65_RS18590 UTRA domain-containing protein 0.75 DZA65_RS20250 methionine synthase low > 75
Acinetobacter baumannii LAC-4 0.33 RR41_RS10960 UTRA domain-containing protein 0.62 RR41_RS08790 methionine synthase low > 55
Escherichia coli ECRC62 0.26 BNILDI_05320 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.76 BNILDI_06140 metH methionine synthase low > 75
Escherichia coli ECOR27 0.26 NOLOHH_06210 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.76 NOLOHH_05380 metH methionine synthase low > 76
Escherichia coli Nissle 1917 0.26 ECOLIN_RS22320 GntR family transcriptional regulator 0.75 ECOLIN_RS23160 methionine synthase low > 55
Escherichia fergusonii Becca 0.26 EFB2_04744 Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons 0.75 EFB2_04592 Methionine synthase low > 86
Escherichia coli ECOR38 0.26 HEPCGN_12710 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.76 HEPCGN_11885 metH methionine synthase low > 88
Escherichia coli ECRC101 0.26 MCAODC_04580 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.76 MCAODC_03740 metH methionine synthase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.26 OHPLBJKB_04180 Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons 0.76 OHPLBJKB_04030 Methionine synthase low > 74
Escherichia coli ECRC102 0.26 NIAGMN_11835 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.76 NIAGMN_10990 metH methionine synthase low > 80
Escherichia coli BW25113 0.26 b3872 yihL predicted DNA-binding transcriptional regulator (NCBI) 0.76 b4019 metH B12-dependent methionine synthase (NCBI) low > 76
Escherichia coli ECRC98 0.26 JDDGAC_17705 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.75 JDDGAC_16865 metH methionine synthase low > 87
Escherichia coli BL21 0.26 ECD_03757 putative DNA-binding transcriptional regulator 0.76 ECD_03891 homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent low > 61
Escherichia coli ECRC99 0.26 KEDOAH_14070 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.76 KEDOAH_14920 metH methionine synthase — —
Escherichia coli ECRC100 0.26 OKFHMN_14080 yihL Uncharacterized HTH-type transcriptional regulator YihL 0.76 OKFHMN_13240 metH methionine synthase low > 79
Herbaspirillum seropedicae SmR1 0.18 HSERO_RS22990 transcriptional regulator 0.61 HSERO_RS21740 methionine synthase low > 78
Azospirillum sp. SherDot2 0.17 MPMX19_03609 HTH-type transcriptional repressor NagR 0.21 MPMX19_00637 Methionine synthase — —
Enterobacter asburiae PDN3 0.16 EX28DRAFT_2262 Transcriptional regulators 0.76 EX28DRAFT_4326 methionine synthase (B12-dependent) (EC 2.1.1.13) low > 76
Rhizobium sp. OAE497 0.16 ABIE40_RS29905 GntR family transcriptional regulator 0.59 ABIE40_RS12135 methionine synthase low > 107
Rhodopseudomonas palustris CGA009 0.15 TX73_003600 phosphonate metabolism transcriptional regulator PhnF 0.60 TX73_019180 methionine synthase low > 86
Enterobacter sp. TBS_079 0.15 MPMX20_01358 Mannosyl-D-glycerate transport/metabolism system repressor MngR 0.75 MPMX20_00235 Methionine synthase low > 85
Klebsiella michiganensis M5al 0.15 BWI76_RS27890 GntR family transcriptional regulator 0.76 BWI76_RS01685 methionine synthase low > 92
Pectobacterium carotovorum WPP14 0.15 HER17_RS16070 GntR family transcriptional regulator 0.76 HER17_RS02310 methionine synthase low > 75
Sinorhizobium meliloti 1021 0.15 SMc03140 transcriptional regulator 0.59 SMc03112 B12-dependent methionine synthase low > 103
Xanthobacter sp. DMC5 0.15 GFF4075 HTH-type transcriptional repressor NagR 0.61 GFF4146 Methionine synthase — —
Pedobacter sp. GW460-11-11-14-LB5 0.12 CA265_RS01265 GntR family transcriptional regulator 0.60 CA265_RS23440 methionine synthase low > 88

Not shown: 20 genomes with orthologs for CSW01_17220 only; 21 genomes with orthologs for CSW01_02060 only