Conservation of cofitness between BWI76_RS20390 and BWI76_RS01275 in Klebsiella michiganensis M5al

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 1.0 BWI76_RS01275 LysR family transcriptional regulator 0.52 10
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.90 GFF253 Transcriptional activator MetR low > 78
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.92 EX28DRAFT_4493 Transcriptional regulator low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.92 MPMX20_04452 HTH-type transcriptional regulator MetR 0.34 50
Escherichia coli BL21 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.92 ECD_03707 methionine biosynthesis regulon transcriptional regulator 0.77 20
Escherichia fergusonii Becca 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.92 EFB2_04809 HTH-type transcriptional regulator MetR low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.92 OHPLBJKB_04223 HTH-type transcriptional regulator MetR low > 73
Escherichia coli Nissle 1917 0.83 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.92 ECOLIN_RS30005 HTH-type transcriptional regulator MetR — —
Escherichia coli BW25113 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.92 b3828 metR DNA-binding transcriptional activator, homocysteine-binding (NCBI) 0.82 4
Escherichia coli ECRC62 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 BNILDI_05070 metR HTH-type transcriptional regulator MetR low > 75
Escherichia coli ECOR27 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 NOLOHH_06460 metR HTH-type transcriptional regulator MetR low > 75
Escherichia coli ECRC101 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 MCAODC_04835 metR HTH-type transcriptional regulator MetR 0.67 65
Escherichia coli ECRC102 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 NIAGMN_12085 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC100 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 OKFHMN_14330 metR HTH-type transcriptional regulator MetR low > 80
Escherichia coli ECRC99 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 KEDOAH_13820 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC98 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 JDDGAC_17955 metR HTH-type transcriptional regulator MetR low > 86
Escherichia coli ECOR38 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.92 HEPCGN_13030 metR HTH-type transcriptional regulator MetR low > 87
Dickeya dadantii 3937 0.75 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB 0.83 DDA3937_RS20385 HTH-type transcriptional regulator MetR low > 74
Dickeya dianthicola ME23 0.74 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB 0.83 DZA65_RS00870 HTH-type transcriptional regulator MetR low > 75
Pantoea sp. MT58 0.73 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.78 IAI47_18315 HTH-type transcriptional regulator MetR 0.69 69
Erwinia tracheiphila SCR3 0.73 LU632_RS07815 DUF3410 domain-containing protein 0.77 LU632_RS24035 metR HTH-type transcriptional regulator MetR — —
Serratia liquefaciens MT49 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.82 IAI46_01030 HTH-type transcriptional regulator MetR low > 86
Rahnella sp. WP5 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.85 EX31_RS25370 HTH-type transcriptional regulator MetR low > 89
Dickeya dianthicola 67-19 0.70 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB 0.83 HGI48_RS00815 HTH-type transcriptional regulator MetR low > 71
Pectobacterium carotovorum WPP14 0.70 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB 0.81 HER17_RS20690 HTH-type transcriptional regulator MetR low > 75
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_10525 DUF3410 domain-containing protein 0.55 CSW01_08580 HTH-type transcriptional regulator MetR — —
Shewanella sp. ANA-3 0.43 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.39 Shewana3_3470 LysR family transcriptional regulator (RefSeq) — —
Shewanella oneidensis MR-1 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.39 SO0817 metR transcriptional activator protein MetR (NCBI ptt file) — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.43 Psyr_3917 transcriptional regulator, LysR family — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.43 Psyr_3917 transcriptional regulator, LysR family — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.42 PfGW456L13_4778 Transcriptional activator MetR — —
Shewanella amazonensis SB2B 0.42 Sama_2153 erythronate-4-phosphate dehydrogenase (RefSeq) 0.37 Sama_2628 transcriptional activator protein MetR (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_00545 erythronate-4-phosphate dehydrogenase 0.42 AO353_16210 XRE family transcriptional regulator — —
Shewanella loihica PV-4 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.36 Shew_2987 LysR family transcriptional regulator (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.42 Pf1N1B4_784 Transcriptional activator MetR — —
Pseudomonas simiae WCS417 0.41 PS417_07535 erythronate-4-phosphate dehydrogenase 0.42 PS417_05455 XRE family transcriptional regulator — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_02365 erythronate-4-phosphate dehydrogenase 0.43 AO356_17735 XRE family transcriptional regulator — —
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.42 Pf6N2E2_5471 Transcriptional activator MetR — —
Pseudomonas fluorescens SBW25 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.42 PFLU_RS05540 LysR family transcriptional regulator — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.42 PFLU_RS05540 LysR family transcriptional regulator — —
Pseudomonas sp. RS175 0.39 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.43 PFR28_03478 HTH-type transcriptional regulator MetR — —
Marinobacter adhaerens HP15 0.38 HP15_2098 erythronate-4-phosphate dehydrogenase 0.32 HP15_458 transcriptional regulator, LysR family protein — —
Pseudomonas putida KT2440 0.38 PP_2117 Erythronate-4-phosphate dehydrogenase 0.42 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding — —
Pseudomonas sp. S08-1 0.37 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.42 OH686_20465 Transcriptional activator MetR — —
Pseudomonas stutzeri RCH2 0.37 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.43 Psest_1450 Transcriptional regulator — —
Alteromonas macleodii MIT1002 0.32 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.29 MIT1002_01119 HTH-type transcriptional regulator GltC — —
Acinetobacter radioresistens SK82 0.31 MPMX26_02238 Erythronate-4-phosphate dehydrogenase 0.35 MPMX26_01201 HTH-type transcriptional regulator MetR low > 36

Not shown: 7 genomes with orthologs for BWI76_RS20390 only; 20 genomes with orthologs for BWI76_RS01275 only