Conservation of cofitness between BWI76_RS00805 and BWI76_RS00785 in Klebsiella michiganensis M5al

42 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 1.0 BWI76_RS00785 cystathionine gamma-synthase 0.91 5
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.94 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.95 EX28DRAFT_4411 cystathionine gamma-synthase (EC 2.5.1.48) 0.64 16
Escherichia coli ECRC62 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.96 BNILDI_05715 metB cystathionine gamma-synthase 0.98 22
Escherichia coli ECOR27 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.96 NOLOHH_05820 metB cystathionine gamma-synthase 0.93 40
Escherichia coli BW25113 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.96 b3939 metB cystathionine gamma-synthase (NCBI) 0.88 51
Enterobacter sp. TBS_079 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.95 MPMX20_04531 Cystathionine gamma-synthase 0.75 14
Escherichia coli BL21 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.96 ECD_03825 cystathionine gamma-synthase, PLP-dependent 0.94 15
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.96 OHPLBJKB_04111 Cystathionine gamma-synthase low > 73
Escherichia coli ECOR38 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.96 HEPCGN_12345 metB cystathionine gamma-synthase 0.97 3
Escherichia coli ECRC98 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.96 JDDGAC_17300 metB cystathionine gamma-synthase 0.99 7
Escherichia coli ECRC102 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.96 NIAGMN_11430 metB cystathionine gamma-synthase
Escherichia coli ECRC101 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.96 MCAODC_04175 metB cystathionine gamma-synthase 0.98 2
Escherichia coli ECRC100 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.96 OKFHMN_13675 metB cystathionine gamma-synthase 0.98 27
Escherichia coli ECRC99 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.96 KEDOAH_14485 metB cystathionine gamma-synthase
Escherichia fergusonii Becca 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.95 EFB2_04679 Cystathionine gamma-synthase low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.96 ECOLIN_RS22725 cystathionine gamma-synthase 0.98 5
Pantoea sp. MT58 0.92 IAI47_00890 methylenetetrahydrofolate reductase 0.82 IAI47_00880 cystathionine gamma-synthase 0.46 55
Serratia liquefaciens MT49 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.82 IAI46_24540 cystathionine gamma-synthase low > 86
Dickeya dadantii 3937 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.87 DDA3937_RS00950 cystathionine gamma-synthase 0.41 30
Rahnella sp. WP5 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.78 EX31_RS14215 cystathionine gamma-synthase 0.95 1
Pectobacterium carotovorum WPP14 0.90 HER17_RS00950 methylenetetrahydrofolate reductase 0.87 HER17_RS00910 cystathionine gamma-synthase low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase 0.87 HGI48_RS20425 cystathionine gamma-synthase low > 71
Dickeya dianthicola ME23 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.87 DZA65_RS21470 cystathionine gamma-synthase 0.77 5
Erwinia tracheiphila SCR3 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.86 LU632_RS19640 metB cystathionine gamma-synthase low > 74
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13560 methylenetetrahydrofolate reductase 0.59 CSW01_13550 O-succinylhomoserine (thiol)-lyase low > 62
Shewanella oneidensis MR-1 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.58 SO4056 metB cystathionine gamma-synthase (NCBI ptt file) 0.99 1
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.60 Sama_3171 cystathionine gamma-synthase (RefSeq) 0.99 1
Shewanella sp. ANA-3 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.60 Shewana3_3614 cystathionine gamma-synthase (RefSeq) 0.97 10
Shewanella loihica PV-4 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.59 Shew_0520 O-succinylhomoserine (thiol)-lyase (RefSeq) 0.99 8
Kangiella aquimarina DSM 16071 0.61 B158DRAFT_2461 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) 0.60 B158DRAFT_2459 cystathionine gamma-synthase (EC 2.5.1.48) low > 40
Azospirillum sp. SherDot2 0.55 MPMX19_00635 5,10-methylenetetrahydrofolate reductase 0.32 MPMX19_06514 L-methionine gamma-lyase low > 112
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H] 0.55 A4249_RS16160 cystathionine gamma-synthase 0.99 22
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.55 Xcc-8004.1596.1 hypothetical protein 0.88 7
Dinoroseobacter shibae DFL-12 0.37 Dshi_2080 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.28 Dshi_1002 Cystathionine gamma-synthase (RefSeq)
Sinorhizobium meliloti 1021 0.37 SMc01843 5,10-methylenetetrahydrofolate reductase 0.51 SMc02595 cystathionine gamma-synthase low > 103
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H] 0.55 LRK54_RS05305 cystathionine gamma-synthase 0.88 1
Rhodanobacter denitrificans MT42 0.37 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] 0.56 LRK55_RS05085 cystathionine gamma-synthase low > 63
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.54 OKGIIK_01515 metB cystathionine gamma-synthase low > 52
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H] 0.54 ABZR86_RS19030 cystathionine gamma-synthase 0.96 7
Lysobacter sp. OAE881 0.35 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] 0.57 ABIE51_RS16185 O-succinylhomoserine (thiol)-lyase 0.97 14
Acidovorax sp. GW101-3H11 0.34 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.31 Ac3H11_34 Methionine gamma-lyase (EC 4.4.1.11) low > 79
Acinetobacter radioresistens SK82 0.32 MPMX26_01002 5,10-methylenetetrahydrofolate reductase 0.33 MPMX26_01645 O-succinylhomoserine sulfhydrylase low > 36

Not shown: 57 genomes with orthologs for BWI76_RS00805 only; 0 genomes with orthologs for BWI76_RS00785 only