Conservation of cofitness between A4249_RS00160 and A4249_RS15340 in Brevundimonas sp. GW460-12-10-14-LB2

37 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Brevundimonas sp. GW460-12-10-14-LB2	1.0	A4249_RS00160		NADP-dependent oxidoreductase	1.0	A4249_RS15340		tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD	0.69	2
Cupriavidus basilensis FW507-4G11	0.64	RR42_RS25545		NADPH:quinone oxidoreductase	0.15	RR42_RS09010		FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 128
Dickeya dadantii 3937	0.64	DDA3937_RS02935		NADP-dependent oxidoreductase	0.19	DDA3937_RS14515		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 74
Ralstonia solanacearum PSI07	0.62	RPSI07_RS04010		NADP-dependent oxidoreductase	0.19	RPSI07_RS16115		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 81
Paraburkholderia graminis OAS925	0.62	ABIE53_005426		NADPH:quinone reductase-like Zn-dependent oxidoreductase	0.17	ABIE53_000291		tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein	low	> 113
Burkholderia phytofirmans PsJN	0.62	BPHYT_RS10180		NADPH:quinone oxidoreductase	0.18	BPHYT_RS19575		tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	low	> 109
Pseudomonas fluorescens SBW25	0.62	PFLU_RS16270		NADP-dependent oxidoreductase	0.21	PFLU_RS21190		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 109
Pseudomonas fluorescens SBW25-INTG	0.62	PFLU_RS16270		NADP-dependent oxidoreductase	0.21	PFLU_RS21190		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 109
Pseudomonas fluorescens FW300-N2C3	0.61	AO356_28615		NADPH:quinone oxidoreductase	0.22	AO356_03570		FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 104
Ralstonia solanacearum IBSBF1503	0.61	RALBFv3_RS16930		NADP-dependent oxidoreductase	0.19	RALBFv3_RS01360		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 76
Ralstonia solanacearum UW163	0.61	UW163_RS18285		NADP-dependent oxidoreductase	0.19	UW163_RS14670		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	—	—
Pseudomonas fluorescens FW300-N2E3	0.59	AO353_28445		NADPH:quinone oxidoreductase	0.21	AO353_02165		FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 101
Pseudomonas fluorescens FW300-N2E2	0.59	Pf6N2E2_1655		Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase	0.21	Pf6N2E2_2541		5-methylaminomethyl-2-thiouridine-forming enzyme mnmC	low	> 103
Pseudomonas fluorescens FW300-N1B4	0.58	Pf1N1B4_4191		Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase	0.21	Pf1N1B4_373		5-methylaminomethyl-2-thiouridine-forming enzyme mnmC	low	> 87
Dickeya dianthicola ME23	0.49	DZA65_RS04690		NADP-dependent oxidoreductase	0.19	DZA65_RS15420		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 75
Paraburkholderia bryophila 376MFSha3.1	0.49	H281DRAFT_05417		NADPH:quinone reductase	0.18	H281DRAFT_02360		tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein	low	> 103
Pantoea sp. MT58	0.49	IAI47_20870		NADP-dependent oxidoreductase	0.22	IAI47_06175		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 76
Pseudomonas sp. RS175	0.49	PFR28_02355		Zinc-type alcohol dehydrogenase-like protein	0.22	PFR28_00884		tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	low	> 88
Pseudomonas putida KT2440	0.48	PP_2988		Alcohol dehydrogenase, zinc-containing	0.20	PP_1751		methyltransferase/FAD-dependent oxidoreductase	low	> 96
Enterobacter sp. TBS_079	0.48	MPMX20_02558		L-threonine 3-dehydrogenase	0.21	MPMX20_03259		tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	low	> 85
Dickeya dianthicola 67-19	0.48	HGI48_RS14000		NADP-dependent oxidoreductase	0.20	HGI48_RS14485		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 71
Pectobacterium carotovorum WPP14	0.47	HER17_RS14295		NADP-dependent oxidoreductase	0.20	HER17_RS06960		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 75
Variovorax sp. OAS795	0.47	ABID97_RS29180		NADP-dependent oxidoreductase	0.18	ABID97_RS15455		FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 91
Pseudomonas syringae pv. syringae B728a	0.45	Psyr_3540		Zinc-containing alcohol dehydrogenase superfamily	0.22	Psyr_3742		FAD dependent oxidoreductase:Protein of unknown function DUF752	low	> 86
Pseudomonas syringae pv. syringae B728a ΔmexB	0.45	Psyr_3540		Zinc-containing alcohol dehydrogenase superfamily	0.22	Psyr_3742		FAD dependent oxidoreductase:Protein of unknown function DUF752	low	> 86
Paraburkholderia sabiae LMG 24235	0.29	QEN71_RS19125		NADP-dependent oxidoreductase	0.17	QEN71_RS29485		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 153
Pseudomonas fluorescens GW456-L13	0.27	PfGW456L13_3135		Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase	0.20	PfGW456L13_2155		tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 87
Alteromonas macleodii MIT1002	0.27	MIT1002_02335		Zinc-type alcohol dehydrogenase-like protein	0.18	MIT1002_02542		tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	low	> 70
Pseudomonas sp. S08-1	0.26	OH686_18595		Zinc-type alcohol dehydrogenase-like protein	0.22	OH686_20990		tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase / FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 80
Pseudomonas simiae WCS417	0.26	PS417_19060		NADPH:quinone oxidoreductase	0.20	PS417_19225		FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 88
Marinobacter adhaerens HP15	0.25	HP15_264		NADPH:quinone reductase and related Zn-dependent oxidoreductase	0.24	HP15_1540		protein YfcK	low	> 73
Serratia liquefaciens MT49	0.25	IAI46_05735		NADP-dependent oxidoreductase	0.20	IAI46_18000		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 86
Acinetobacter radioresistens SK82	0.23	MPMX26_00861		Mycocerosic acid synthase-like polyketide synthase	0.23	MPMX26_02642		tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC	low	> 36
Variovorax sp. SCN45	0.23	GFF252		Zinc-type alcohol dehydrogenase-like protein	0.18	GFF1245		tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 127
Acidovorax sp. GW101-3H11	0.22	Ac3H11_2900		alcohol dehydrogenase, zinc containing	0.17	Ac3H11_579		tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase	low	> 79
Herbaspirillum seropedicae SmR1	0.22	HSERO_RS17470		NADPH-quinone reductase	0.10	HSERO_RS23825		hypothetical protein	—	—
Ralstonia sp. UNC404CL21Col	0.18	ABZR87_RS05920		zinc-binding alcohol dehydrogenase family protein	0.19	ABZR87_RS12805		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 80
Klebsiella michiganensis M5al	0.16	BWI76_RS27625		NADPH:quinone reductase	0.20	BWI76_RS20410		bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	low	> 92

Not shown: 15 genomes with orthologs for A4249_RS00160 only; 25 genomes with orthologs for A4249_RS15340 only