Conservation of cofitness between b0674 and b3828 in Escherichia coli BW25113

42 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0674 asnB asparagine synthetase B (NCBI) 1.0 b3828 metR DNA-binding transcriptional activator, homocysteine-binding (NCBI) 0.32 9
Escherichia coli ECOR38 1.00 HEPCGN_01050 asnB asparagine synthase B 1.00 HEPCGN_13030 metR HTH-type transcriptional regulator MetR low > 85
Escherichia fergusonii Becca 1.00 EFB2_03429 Asparagine synthetase B [glutamine-hydrolyzing] 1.00 EFB2_04809 HTH-type transcriptional regulator MetR low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS03600 asparagine synthase B 1.00 ECOLIN_RS30005 HTH-type transcriptional regulator MetR — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03042 Asparagine synthetase B [glutamine-hydrolyzing] 1.00 OHPLBJKB_04223 HTH-type transcriptional regulator MetR low > 73
Escherichia coli BL21 1.00 ECD_00631 asparagine synthetase B 1.00 ECD_03707 methionine biosynthesis regulon transcriptional regulator low > 60
Escherichia coli ECOR27 1.00 NOLOHH_23560 asnB asparagine synthase B 1.00 NOLOHH_06460 metR HTH-type transcriptional regulator MetR low > 57
Escherichia coli ECRC62 1.00 BNILDI_21565 asnB asparagine synthase B 1.00 BNILDI_05070 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC98 1.00 JDDGAC_10830 asnB asparagine synthase B 1.00 JDDGAC_17955 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC99 1.00 KEDOAH_20790 asnB asparagine synthase B 1.00 KEDOAH_13820 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC101 1.00 MCAODC_26395 asnB asparagine synthase B 1.00 MCAODC_04835 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC102 1.00 NIAGMN_05235 asnB asparagine synthase B 1.00 NIAGMN_12085 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC101 0.99 OKFHMN_07180 asnB asparagine synthase B 1.00 OKFHMN_14330 metR HTH-type transcriptional regulator MetR — —
Enterobacter asburiae PDN3 0.96 EX28DRAFT_2301 asparagine synthase (glutamine-hydrolyzing) 0.94 EX28DRAFT_4493 Transcriptional regulator low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF4582 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) 0.92 GFF253 Transcriptional activator MetR low > 78
Enterobacter sp. TBS_079 0.95 MPMX20_01320 Asparagine synthetase B [glutamine-hydrolyzing] 0.94 MPMX20_04452 HTH-type transcriptional regulator MetR low > 85
Klebsiella michiganensis M5al 0.95 BWI76_RS08180 asparagine synthase B 0.88 BWI76_RS01275 LysR family transcriptional regulator low > 92
Pectobacterium carotovorum WPP14 0.94 HER17_RS15120 asparagine synthase B 0.84 HER17_RS20690 HTH-type transcriptional regulator MetR 0.71 10
Serratia liquefaciens MT49 0.94 IAI46_06065 asparagine synthase B 0.83 IAI46_01030 HTH-type transcriptional regulator MetR low > 86
Dickeya dianthicola ME23 0.93 DZA65_RS06685 asparagine synthase B 0.87 DZA65_RS00870 HTH-type transcriptional regulator MetR 0.77 23
Dickeya dianthicola 67-19 0.93 HGI48_RS06340 asparagine synthase B 0.87 HGI48_RS00815 HTH-type transcriptional regulator MetR low > 71
Rahnella sp. WP5 0.92 EX31_RS23245 asparagine synthase B 0.88 EX31_RS25370 HTH-type transcriptional regulator MetR low > 89
Erwinia tracheiphila SCR3 0.87 LU632_RS16265 asnB asparagine synthase B 0.78 LU632_RS24035 metR HTH-type transcriptional regulator MetR — —
Pantoea sp. MT58 0.86 IAI47_13900 asparagine synthase B 0.80 IAI47_18315 HTH-type transcriptional regulator MetR 0.77 72
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_05055 asparagine synthase B 0.55 CSW01_08580 HTH-type transcriptional regulator MetR low > 62
Alteromonas macleodii MIT1002 0.73 MIT1002_01266 Asparagine synthetase B [glutamine-hydrolyzing] 0.29 MIT1002_01119 HTH-type transcriptional regulator GltC low > 70
Shewanella oneidensis MR-1 0.72 SO2767 asnB-1 asparagine synthetase B, glutamine-hydrolyzing (NCBI ptt file) 0.38 SO0817 metR transcriptional activator protein MetR (NCBI ptt file) 0.75 59
Shewanella sp. ANA-3 0.72 Shewana3_2549 asnB asparagine synthetase B (RefSeq) 0.38 Shewana3_3470 LysR family transcriptional regulator (RefSeq) low > 73
Shewanella loihica PV-4 0.71 Shew_1509 asnB asparagine synthetase B (RefSeq) 0.35 Shew_2987 LysR family transcriptional regulator (RefSeq) low > 60
Shewanella amazonensis SB2B 0.71 Sama_2101 asnB asparagine synthetase B (RefSeq) 0.37 Sama_2628 transcriptional activator protein MetR (RefSeq) 0.92 17
Xanthomonas campestris pv. campestris strain 8004 0.57 Xcc-8004.3537.1 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) 0.32 Xcc-8004.400.1 Transcriptional activator MetR low > 74
Azospirillum brasilense Sp245 0.15 AZOBR_RS22535 asparagine synthase 0.29 AZOBR_RS24270 LysR family transcriptional regulator low > 97
Pseudomonas simiae WCS417 0.13 PS417_19230 asparagine synthase 0.42 PS417_05455 XRE family transcriptional regulator low > 88
Pseudomonas sp. S08-1 0.13 OH686_20985 asparagine synthase (glutamine-hydrolyzing) 0.43 OH686_20465 Transcriptional activator MetR low > 80
Pseudomonas fluorescens FW300-N2E2 0.13 Pf6N2E2_2542 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) 0.42 Pf6N2E2_5471 Transcriptional activator MetR low > 103
Pseudomonas fluorescens SBW25-INTG 0.13 PFLU_RS21200 N-acetylglutaminylglutamine amidotransferase 0.42 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.13 PFLU_RS21200 N-acetylglutaminylglutamine amidotransferase 0.42 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens GW456-L13 0.13 PfGW456L13_2154 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) 0.42 PfGW456L13_4778 Transcriptional activator MetR low > 87
Pseudomonas fluorescens FW300-N1B4 0.13 Pf1N1B4_374 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) 0.42 Pf1N1B4_784 Transcriptional activator MetR low > 87
Pseudomonas fluorescens FW300-N2C3 0.13 AO356_03575 asparagine synthase 0.43 AO356_17735 XRE family transcriptional regulator low > 104
Pseudomonas stutzeri RCH2 0.12 Psest_2930 asparagine synthase (glutamine-hydrolyzing) 0.43 Psest_1450 Transcriptional regulator — —
Pseudomonas putida KT2440 0.11 PP_1750 asparagine synthetase 0.42 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding low > 96
Acidovorax sp. GW101-3H11 0.11 Ac3H11_1552 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) 0.35 Ac3H11_2344 Transcriptional activator MetR low > 79

Not shown: 17 genomes with orthologs for b0674 only; 24 genomes with orthologs for b3828 only