| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b3650 | spoT | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | 1.0 | b2022 | hisB | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | 0.75 | 2 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_00051 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.99 | OHPLBJKB_01678 | | Histidine biosynthesis bifunctional protein HisB | low | > 73 |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_15555 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | OKFHMN_24505 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_13315 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | NIAGMN_22450 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_14375 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.99 | HEPCGN_03210 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 85 |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_19180 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | JDDGAC_28615 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_06065 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | MCAODC_20435 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_07435 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | NOLOHH_15820 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_12590 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | KEDOAH_03645 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS20790 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.99 | ECOLIN_RS11955 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Escherichia fergusonii Becca | 1.00 | EFB2_00138 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.99 | EFB2_01834 | | Histidine biosynthesis bifunctional protein HisB | low | > 86 |
| Escherichia coli BL21 | 1.00 | ECD_03507 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.99 | ECD_01924 | | histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase | low | > 60 |
| Escherichia coli ECRC62 | 1.00 | BNILDI_04080 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.99 | BNILDI_14730 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.98 | GFF357 | | 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 | 0.96 | GFF3910 | | Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) | low | > 78 |
| Enterobacter asburiae PDN3 | 0.97 | EX28DRAFT_3899 | | (p)ppGpp synthetase, RelA/SpoT family | 0.91 | EX28DRAFT_0537 | | imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) | low | > 76 |
| Enterobacter sp. TBS_079 | 0.97 | MPMX20_00086 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.92 | MPMX20_03004 | | Histidine biosynthesis bifunctional protein HisB | 0.42 | 36 |
| Klebsiella michiganensis M5al | 0.96 | BWI76_RS27430 | | (p)ppGpp synthetase | 0.88 | BWI76_RS18935 | | bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase | low | > 92 |
| Pantoea sp. MT58 | 0.93 | IAI47_00510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.82 | IAI47_07080 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 76 |
| Serratia liquefaciens MT49 | 0.92 | IAI46_24895 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.84 | IAI46_08200 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 86 |
| Erwinia tracheiphila SCR3 | 0.92 | LU632_RS22200 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.83 | LU632_RS08935 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 74 |
| Rahnella sp. WP5 | 0.91 | EX31_RS15810 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.83 | EX31_RS11450 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 89 |
| Dickeya dianthicola ME23 | 0.91 | DZA65_RS22150 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.84 | DZA65_RS10045 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Dickeya dianthicola 67-19 | 0.91 | HGI48_RS21180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.84 | HGI48_RS09735 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Pectobacterium carotovorum WPP14 | 0.91 | HER17_RS21385 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.83 | HER17_RS12240 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 75 |
| Dickeya dadantii 3937 | 0.90 | DDA3937_RS00180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.84 | DDA3937_RS09725 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.75 | CSW01_13675 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | 0.68 | CSW01_05760 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase | low | > 62 |
| Shewanella amazonensis SB2B | 0.71 | Sama_0264 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.64 | Sama_1944 | | imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) | low | > 62 |
| Shewanella loihica PV-4 | 0.71 | Shew_3499 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.66 | Shew_2200 | | imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) | low | > 60 |
| Shewanella oneidensis MR-1 | 0.71 | SO0359 | spoT | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) | 0.63 | SO2071 | hisB | imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.70 | Shewana3_3812 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.63 | Shewana3_1851 | | imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) | low | > 73 |
| Alteromonas macleodii MIT1002 | 0.62 | MIT1002_00108 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.65 | MIT1002_02635 | | Histidine biosynthesis bifunctional protein HisB | low | > 70 |
| Dyella japonica UNC79MFTsu3.2 | 0.48 | ABZR86_RS11850 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.54 | ABZR86_RS06720 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.48 | LRK54_RS11795 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.53 | LRK54_RS01595 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Rhodanobacter denitrificans MT42 | 0.48 | LRK55_RS11520 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.53 | LRK55_RS01375 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Rhodanobacter sp. FW510-T8 | 0.48 | OKGIIK_12100 | spoT | guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | 0.52 | OKGIIK_04960 | hisB | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Lysobacter sp. OAE881 | 0.46 | ABIE51_RS17265 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.54 | ABIE51_RS13315 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.45 | Xcc-8004.1215.1 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.53 | Xcc-8004.2946.1 | | Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.32 | CA265_RS14485 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.42 | CA265_RS03625 | | bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase | 0.60 | 18 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.31 | ABZR88_RS15610 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.43 | ABZR88_RS06870 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | low | > 71 |
| Phocaeicola dorei CL03T12C01 | 0.31 | ABI39_RS09710 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.44 | ABI39_RS11845 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Phocaeicola vulgatus CL09T03C04 | 0.31 | HMPREF1058_RS14060 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.44 | HMPREF1058_RS15885 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.30 | CA264_01425 | | RelA/SpoT family protein | 0.47 | CA264_05040 | | bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase | low | > 74 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.29 | BT3998 | | GTP pyrophosphokinase (NCBI ptt file) | 0.46 | BT0203 | | histidine biosynthesis bifunctional protein hisB (NCBI ptt file) | — | — |
| Bacteroides ovatus ATCC 8483 | 0.29 | BACOVA_04817 | | RelA/SpoT family protein | 0.46 | BACOVA_01232 | | histidinol-phosphatase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.29 | Echvi_4631 | | (p)ppGpp synthetase, RelA/SpoT family | 0.44 | Echvi_2457 | | histidinol-phosphatase | 0.41 | 40 |
| Bacteroides stercoris CC31F | 0.29 | HMPREF1181_RS09205 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.46 | HMPREF1181_RS04850 | | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | — | — |
Not shown: 54 genomes with orthologs for b3650 only; 1 genomes with orthologs for b2022 only