Conservation of cofitness between b3846 and b1014 in Escherichia coli BW25113

48 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3846 fadB fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (NCBI) 1.0 b1014 putA fused DNA-binding transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (NCBI) 0.22 18
Escherichia coli ECOR27 1.00 NOLOHH_06375 fadB fatty acid oxidation complex subunit alpha FadB 1.00 NOLOHH_21505 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04207 Fatty acid oxidation complex subunit alpha 0.99 OHPLBJKB_02652 Bifunctional protein PutA low > 73
Escherichia coli ECOR38 0.99 HEPCGN_12875 fadB fatty acid oxidation complex subunit alpha FadB 0.99 HEPCGN_23535 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 85
Escherichia coli BL21 0.99 ECD_03737 fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase 1.00 ECD_01017 fused DNA-binding transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase low > 60
Escherichia coli ECRC62 0.99 BNILDI_05155 fadB fatty acid oxidation complex subunit alpha FadB 1.00 BNILDI_19670 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia coli ECRC101 0.99 OKFHMN_14245 fadB fatty acid oxidation complex subunit alpha FadB 1.00 OKFHMN_04605 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia coli ECRC98 0.99 JDDGAC_17870 fadB fatty acid oxidation complex subunit alpha FadB 1.00 JDDGAC_08215 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia coli ECRC99 0.99 KEDOAH_13905 fadB fatty acid oxidation complex subunit alpha FadB 1.00 KEDOAH_23140 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia coli ECRC102 0.99 NIAGMN_12000 fadB fatty acid oxidation complex subunit alpha FadB 1.00 NIAGMN_23730 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia coli ECRC101 0.99 MCAODC_04750 fadB fatty acid oxidation complex subunit alpha FadB 1.00 MCAODC_23990 putA trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Escherichia fergusonii Becca 0.99 EFB2_04771 Fatty acid oxidation complex subunit alpha 0.99 EFB2_03066 Bifunctional protein PutA low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF273 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.91 GFF3301 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) low > 78
Klebsiella michiganensis M5al 0.92 BWI76_RS01365 multifunctional fatty acid oxidation complex subunit alpha 0.90 BWI76_RS10795 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) 0.20 60
Enterobacter sp. TBS_079 0.91 MPMX20_04436 Fatty acid oxidation complex subunit alpha 0.90 MPMX20_01702 Bifunctional protein PutA low > 85
Enterobacter asburiae PDN3 0.91 EX28DRAFT_4510 fatty oxidation complex, alpha subunit FadB 0.90 EX28DRAFT_1911 L-proline dehydrogenase (EC 1.5.99.8)/delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 76
Serratia liquefaciens MT49 0.77 IAI46_01130 fatty acid oxidation complex subunit alpha FadB 0.80 IAI46_15745 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 86
Pectobacterium carotovorum WPP14 0.76 HER17_RS20550 fatty acid oxidation complex subunit alpha FadB 0.73 HER17_RS01110 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 75
Rahnella sp. WP5 0.74 EX31_RS14565 fatty acid oxidation complex subunit alpha FadB 0.79 EX31_RS09420 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 89
Pantoea sp. MT58 0.73 IAI47_18230 fatty acid oxidation complex subunit alpha FadB 0.81 IAI47_08195 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 76
Dickeya dadantii 3937 0.67 DDA3937_RS20250 fatty acid oxidation complex subunit alpha FadB 0.75 DDA3937_RS20115 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 74
Dickeya dianthicola 67-19 0.65 HGI48_RS00975 fatty acid oxidation complex subunit alpha FadB 0.73 HGI48_RS20255 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 71
Dickeya dianthicola ME23 0.65 DZA65_RS01035 fatty acid oxidation complex subunit alpha FadB 0.73 DZA65_RS21300 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 75
Alteromonas macleodii MIT1002 0.55 MIT1002_00575 Fatty acid oxidation complex subunit alpha 0.38 MIT1002_00637 Bifunctional protein PutA low > 70
Pseudomonas putida KT2440 0.54 PP_2136 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase 0.74 PP_4947 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase low > 96
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_3290 3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase 0.73 Psyr_0506 L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_3290 3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase 0.73 Psyr_0506 L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase low > 86
Pseudomonas simiae WCS417 0.54 PS417_07575 multifunctional fatty acid oxidation complex subunit alpha 0.74 PS417_02175 transcriptional regulator low > 88
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS07650 fatty acid oxidation complex subunit alpha FadB 0.74 PFLU_RS02230 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.54 PFLU_RS07650 fatty acid oxidation complex subunit alpha FadB 0.74 PFLU_RS02230 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 109
Pseudomonas sp. RS175 0.54 PFR28_01110 Fatty acid oxidation complex subunit alpha 0.74 PFR28_05053 Bifunctional protein PutA low > 88
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_2290 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.74 Pf6N2E2_3685 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) — —
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_02330 multifunctional fatty acid oxidation complex subunit alpha 0.74 AO356_09015 transcriptional regulator — —
Pseudomonas fluorescens FW300-N1B4 0.54 Pf1N1B4_3903 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.74 Pf1N1B4_1489 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) — —
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_4041 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.74 PfGW456L13_223 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 87
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_00510 multifunctional fatty acid oxidation complex subunit alpha 0.75 AO353_12810 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 101
Marinobacter adhaerens HP15 0.53 HP15_1512 Enoyl-CoA hydratase (EC 4.2.1.17) (from data) 0.37 HP15_2688 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 73
Pseudomonas sp. S08-1 0.53 OH686_21925 fatty oxidation complex, alpha subunit FadB 0.70 OH686_06735 Transcriptional repressor of PutA and PutP / Proline dehydrogenase / Delta-1-pyrroline-5-carboxylate dehydrogenase low > 80
Acinetobacter radioresistens SK82 0.50 MPMX26_00226 Fatty acid oxidation complex subunit alpha 0.53 MPMX26_01466 Bifunctional protein PutA low > 36
Paraburkholderia bryophila 376MFSha3.1 0.24 H281DRAFT_00916 short chain enoyl-CoA hydratase /3-hydroxyacyl-CoA dehydrogenase 0.63 H281DRAFT_02404 L-proline dehydrogenase /delta-1-pyrroline-5-carboxylate dehydrogenase low > 103
Burkholderia phytofirmans PsJN 0.23 BPHYT_RS09560 3-hydroxyacyl-CoA dehydrogenase 0.64 BPHYT_RS19355 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase low > 109
Paraburkholderia sabiae LMG 24235 0.23 QEN71_RS21890 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein 0.63 QEN71_RS29240 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 153
Ralstonia sp. UNC404CL21Col 0.23 ABZR87_RS12585 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein 0.68 ABZR87_RS03970 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 80
Ralstonia solanacearum GMI1000 0.22 RS_RS08885 3-hydroxyacyl-CoA dehydrogenase 0.67 RS_RS16540 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 80
Ralstonia solanacearum PSI07 0.22 RPSI07_RS16345 3-hydroxyacyl-CoA dehydrogenase 0.67 RPSI07_RS08540 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 81
Sphingomonas koreensis DSMZ 15582 0.22 Ga0059261_0837 3-hydroxyacyl-CoA dehydrogenase 0.48 Ga0059261_3926 L-proline dehydrogenase (EC 1.5.99.8)/delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) low > 68
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS01130 3-hydroxyacyl-CoA dehydrogenase 0.67 RALBFv3_RS08725 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase low > 76
Ralstonia solanacearum UW163 0.22 UW163_RS14440 3-hydroxyacyl-CoA dehydrogenase 0.67 UW163_RS04885 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS11095 3-hydroxyacyl-CoA dehydrogenase 0.68 RR42_RS20125 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) low > 128

Not shown: 9 genomes with orthologs for b3846 only; 15 genomes with orthologs for b1014 only