Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Bifidobacterium breve UCC2003 | BBR_RS15295 | | Cof-type HAD-IIB family hydrolase | sig. | 100 | 100 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS02885 | | Cof-type HAD-IIB family hydrolase | insig. | 27 | 98 |
| Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS08655 | | Cof-type HAD-IIB family hydrolase | insig. | 27 | 98 |
| Bacteroides thetaiotaomicron VPI-5482 | BT4131 | | conserved hypothetical protein (NCBI ptt file) | sig. | 26 | 99 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS07825 | | Cof-type HAD-IIB family hydrolase | insig. | 26 | 98 |
| Bacteroides stercoris CC31F | HMPREF1181_RS06415 | | Cof-type HAD-IIB family hydrolase | insig. | 26 | 98 |
o | Pantoea sp. MT58 | IAI47_00025 | | sugar-phosphatase | insig. | 26 | 98 |
| Bacteroides ovatus ATCC 8483 | BACOVA_04941 | | Cof-like hydrolase | insig. | 25 | 99 |
| Bacteroides ovatus ATCC 8483 | BACOVA_02204 | | Cof-like hydrolase | insig. | 26 | 95 |
| Serratia liquefaciens MT49 | IAI46_00025 | | sugar-phosphatase | insig. | 27 | 98 |
| Bifidobacterium breve UCC2003 | BBR_RS14440 | | Cof-type HAD-IIB family hydrolase | sig. | 29 | 98 |
| Rahnella sp. WP5 | EX31_RS05965 | | sugar-phosphatase | insig. | 25 | 98 |
| Bacteroides thetaiotaomicron VPI-5482 | BT1666 | | hydrolase, haloacid dehalogenase-like hydrolase (NCBI ptt file) | insig. | 26 | 96 |
| Pseudomonas sp. RS175 | PFR28_01675 | | Sugar phosphatase YidA | insig. | 26 | 96 |
| Dickeya dianthicola ME23 | DZA65_RS21990 | | sugar-phosphatase | insig. | 26 | 98 |
| Dickeya dianthicola 67-19 | HGI48_RS21005 | | sugar-phosphatase | insig. | 25 | 98 |
| Pseudomonas fluorescens SBW25 | PFLU_RS13145 | | Cof-type HAD-IIB family hydrolase | insig. | 24 | 98 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS13145 | | Cof-type HAD-IIB family hydrolase | insig. | 24 | 98 |
o | Mycobacterium tuberculosis H37Rv | Rv3813c | | Conserved protein | sig. | 29 | 98 |
| Escherichia coli ECOR27 | NOLOHH_07185 | yidA | sugar-phosphatase | cofit | 38 | 31 |
| Erwinia tracheiphila SCR3 | LU632_RS00030 | yidA | sugar-phosphatase | insig. | 38 | 31 |
| Escherichia coli BL21 | ECD_03580 | | sugar phosphate phosphatase | cofit | 38 | 31 |
| Escherichia fergusonii Becca | EFB2_00006 | | Sugar phosphatase YidA | insig. | 38 | 31 |
| Escherichia coli ECOR38 | HEPCGN_13750 | yidA | sugar-phosphatase | cofit | 38 | 31 |
| Escherichia coli ECRC101 | OKFHMN_15045 | yidA | sugar-phosphatase | insig. | 38 | 31 |
| Escherichia coli ECRC101 | MCAODC_05555 | yidA | sugar-phosphatase | insig. | 38 | 31 |
| Escherichia coli ECRC102 | NIAGMN_12800 | yidA | sugar-phosphatase | insig. | 38 | 31 |
| Escherichia coli ECRC62 | BNILDI_04345 | yidA | sugar-phosphatase | insig. | 38 | 31 |
| Escherichia coli ECRC98 | JDDGAC_18665 | yidA | sugar-phosphatase | no data | 38 | 31 |
| Escherichia coli ECRC99 | KEDOAH_13105 | yidA | sugar-phosphatase | no data | 38 | 31 |
| Escherichia coli Nissle 1917 | ECOLIN_RS21290 | | sugar-phosphatase | insig. | 38 | 31 |
| Escherichia coli BW25113 | b3697 | yidA | predicted hydrolase (NCBI) | insig. | 38 | 31 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00006 | | Sugar phosphatase YidA | insig. | 38 | 30 |
| Pseudomonas simiae WCS417 | PS417_12455 | | hydrolase | insig. | 24 | 98 |
| Enterobacter asburiae PDN3 | EX28DRAFT_3983 | | HAD-superfamily hydrolase, subfamily IIB | insig. | 36 | 31 |
| Bacteroides thetaiotaomicron VPI-5482 | BT3352 | | haloacid dehalogenase-like hydrolase (NCBI ptt file) | sig. | 22 | 97 |
| Klebsiella michiganensis M5al | BWI76_RS27955 | | sugar-phosphatase | insig. | 38 | 30 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_06865 | | Cof-type HAD-IIB family hydrolase | cofit | 24 | 98 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1761 | | Promiscuous sugar phosphatase YidA, haloacid dehalogenase-like phosphatase family | insig. | 36 | 31 |
| Bacteroides ovatus ATCC 8483 | BACOVA_01965 | | Cof-like hydrolase | insig. | 22 | 96 |
| Enterobacter sp. TBS_079 | MPMX20_00007 | | Sugar phosphatase YidA | insig. | 36 | 31 |
| Erwinia tracheiphila SCR3 | LU632_RS24075 | yigL | sugar/pyridoxal phosphate phosphatase YigL | sig. | 25 | 87 |
| Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS04265 | | Cof-type HAD-IIB family hydrolase | sig. | 23 | 95 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS16940 | | Cof-type HAD-IIB family hydrolase | sig. | 23 | 95 |
| Pectobacterium carotovorum WPP14 | HER17_RS00065 | | sugar-phosphatase | insig. | 26 | 98 |
| Bacteroides stercoris CC31F | HMPREF1181_RS02400 | | Cof-type HAD-IIB family hydrolase | insig. | 23 | 98 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_27845 | | hydrolase | insig. | 26 | 96 |
| Pseudomonas syringae pv. syringae B728a | Psyr_2987 | | Cof protein:HAD-superfamily hydrolase, subfamily IIB | insig. | 24 | 96 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2987 | | Cof protein:HAD-superfamily hydrolase, subfamily IIB | insig. | 24 | 96 |
| Dickeya dadantii 3937 | DDA3937_RS00365 | | sugar-phosphatase | insig. | 37 | 29 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_15185 | | Cof-type HAD-IIB family hydrolase | insig. | 25 | 96 |
| Bacteroides stercoris CC31F | HMPREF1181_RS11870 | | Cof-type HAD-IIB family hydrolase | insig. | 22 | 98 |
| Dickeya dadantii 3937 | DDA3937_RS19825 | | sugar/pyridoxal phosphate phosphatase YigL | insig. | 27 | 87 |
| Dickeya dianthicola ME23 | DZA65_RS21025 | | sugar/pyridoxal phosphate phosphatase YigL | insig. | 27 | 87 |
| Bacteroides ovatus ATCC 8483 | BACOVA_05549 | | Cof-like hydrolase | strong | 21 | 96 |
| Bifidobacterium breve UCC2003 | BBR_RS15715 | | Cof-type HAD-IIB family hydrolase | strong | 21 | 97 |
| Sinorhizobium meliloti 1021 | SMc04299 | | hypothetical protein | insig. | 22 | 93 |
| Dickeya dianthicola 67-19 | HGI48_RS19980 | | sugar/pyridoxal phosphate phosphatase YigL | cofit | 27 | 87 |
| Klebsiella michiganensis M5al | BWI76_RS01265 | | sugar/pyridoxal phosphate phosphatase YigL | insig. | 25 | 88 |
| Serratia liquefaciens MT49 | IAI46_05055 | | HMP-PP phosphatase | insig. | 25 | 88 |
| Serratia liquefaciens MT49 | IAI46_00790 | | sugar/pyridoxal phosphate phosphatase YigL | insig. | 26 | 86 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4727 | | HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217) | insig. | 24 | 96 |
| Pantoea sp. MT58 | IAI47_18335 | | sugar/pyridoxal phosphate phosphatase YigL | insig. | 34 | 32 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF252 | | Cof protein, HD superfamily hydrolase | insig. | 26 | 88 |
| Rhodopseudomonas palustris CGA009 | TX73_018860 | | Cof-type HAD-IIB family hydrolase | insig. | 24 | 97 |
| Klebsiella michiganensis M5al | BWI76_RS06570 | | thiamin pyrimidine pyrophosphate hydrolase | insig. | 24 | 88 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS08065 | | Cof-type HAD-IIB family hydrolase | sig. | 23 | 96 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF721 | | HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217) | insig. | 33 | 28 |
| Escherichia coli Nissle 1917 | ECOLIN_RS21965 | | sugar/pyridoxal phosphate phosphatase YigL | no data | 26 | 88 |
| Escherichia coli BL21 | ECD_03705 | | pyridoxal phosphate phosphatase | insig. | 26 | 88 |
| Escherichia coli ECOR38 | HEPCGN_13040 | yigL | sugar/pyridoxal phosphate phosphatase YigL | cofit | 26 | 88 |
| Escherichia fergusonii Becca | EFB2_04811 | | Pyridoxal phosphate phosphatase YigL | insig. | 26 | 88 |
| Escherichia coli ECOR27 | NOLOHH_06470 | yigL | sugar/pyridoxal phosphate phosphatase YigL | cofit | 26 | 88 |
| Escherichia coli ECRC101 | MCAODC_04845 | yigL | sugar/pyridoxal phosphate phosphatase YigL | insig. | 26 | 88 |
| Escherichia coli ECRC62 | BNILDI_05060 | yigL | sugar/pyridoxal phosphate phosphatase YigL | insig. | 26 | 88 |
| Escherichia coli ECRC98 | JDDGAC_17965 | yigL | sugar/pyridoxal phosphate phosphatase YigL | no data | 26 | 88 |
| Escherichia coli ECRC99 | KEDOAH_13810 | yigL | sugar/pyridoxal phosphate phosphatase YigL | no data | 26 | 88 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_04225 | | Pyridoxal phosphate phosphatase YigL | insig. | 26 | 88 |
| Escherichia coli BW25113 | b3826 | yigL | predicted hydrolase (NCBI) | insig. | 26 | 88 |
| Escherichia coli ECOR38 | HEPCGN_01890 | ybiV | sugar-phosphatase YbiV | cofit | 32 | 28 |
| Enterobacter sp. TBS_079 | MPMX20_01462 | | Sugar phosphatase YbiV | insig. | 30 | 28 |
| Escherichia coli ECRC101 | OKFHMN_14340 | yigL | sugar/pyridoxal phosphate phosphatase YigL | insig. | 26 | 88 |
| Escherichia coli ECRC102 | NIAGMN_12095 | yigL | sugar/pyridoxal phosphate phosphatase YigL | insig. | 26 | 88 |
| Escherichia coli BL21 | ECD_00789 | | sugar phosphatase; fructose-1-P/ribose-5-P/glucose-6-P phosphatase | insig. | 32 | 28 |
| Escherichia fergusonii Becca | EFB2_03284 | | Sugar phosphatase YbiV | insig. | 32 | 28 |
| Escherichia coli ECOR27 | NOLOHH_22495 | ybiV | sugar-phosphatase YbiV | insig. | 32 | 28 |
| Escherichia coli ECRC101 | OKFHMN_06150 | ybiV | sugar-phosphatase YbiV | insig. | 32 | 28 |
| Escherichia coli ECRC101 | MCAODC_25365 | ybiV | sugar-phosphatase YbiV | insig. | 32 | 28 |
| Escherichia coli ECRC102 | NIAGMN_04195 | ybiV | sugar-phosphatase YbiV | insig. | 32 | 28 |
| Escherichia coli ECRC62 | BNILDI_20775 | ybiV | sugar-phosphatase YbiV | insig. | 32 | 28 |
| Escherichia coli ECRC98 | JDDGAC_09785 | ybiV | sugar-phosphatase YbiV | no data | 32 | 28 |
| Escherichia coli ECRC99 | KEDOAH_21760 | ybiV | sugar-phosphatase YbiV | no data | 32 | 28 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02890 | | Sugar phosphatase YbiV | insig. | 32 | 28 |
| Escherichia coli BW25113 | b0822 | ybiV | predicted hydrolase (NCBI) | insig. | 32 | 28 |
| Klebsiella michiganensis M5al | BWI76_RS08660 | | pyridoxal phosphatase | insig. | 43 | 20 |
| Klebsiella michiganensis M5al | BWI76_RS09065 | | sugar phosphatase SupH | sig. | 33 | 28 |
| Escherichia coli ECRC101 | OKFHMN_06680 | ybhA | bifunctional pyridoxal phosphate/fructose-1,6-bisphosphate phosphatase | insig. | 24 | 94 |
| Escherichia coli ECRC101 | MCAODC_25900 | ybhA | bifunctional pyridoxal phosphate/fructose-1,6-bisphosphate phosphatase | insig. | 24 | 94 |
| Escherichia coli ECRC102 | NIAGMN_04730 | ybhA | bifunctional pyridoxal phosphate/fructose-1,6-bisphosphate phosphatase | insig. | 24 | 94 |
| Escherichia coli ECRC98 | JDDGAC_10335 | ybhA | bifunctional pyridoxal phosphate/fructose-1,6-bisphosphate phosphatase | no data | 24 | 94 |