Conservation of cofitness between PP_3376 and PP_1063 in Pseudomonas putida KT2440

40 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_3376 putative phosphonate dehydrogenase 1.0 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding 0.50 4
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_26885 phosphogluconate 2-dehydrogenase KguD (EC 1.1.1.43) (from data) 0.95 AO353_16210 XRE family transcriptional regulator low > 101
Pseudomonas fluorescens GW456-L13 0.74 PfGW456L13_2948 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.95 PfGW456L13_4778 Transcriptional activator MetR low > 87
Pseudomonas sp. RS175 0.73 PFR28_01596 Glyoxylate/hydroxypyruvate reductase B 0.96 PFR28_03478 HTH-type transcriptional regulator MetR low > 88
Pseudomonas fluorescens FW300-N1B4 0.73 Pf1N1B4_4763 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.95 Pf1N1B4_784 Transcriptional activator MetR low > 87
Pseudomonas simiae WCS417 0.73 PS417_12555 phosphogluconate 2-dehydrogenase KguD (EC 1.1.1.43) (from data) 0.94 PS417_05455 XRE family transcriptional regulator low > 88
Pseudomonas fluorescens FW300-N2E2 0.72 Pf6N2E2_627 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.95 Pf6N2E2_5471 Transcriptional activator MetR low > 103
Pseudomonas fluorescens SBW25-INTG 0.72 PFLU_RS13240 D-glycerate dehydrogenase 0.95 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.72 PFLU_RS13240 D-glycerate dehydrogenase 0.95 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens FW300-N2C3 0.70 AO356_24675 bifunctional glyoxylate/hydroxypyruvate reductase B 0.95 AO356_17735 XRE family transcriptional regulator low > 104
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS11290 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) (from data) 0.46 BPHYT_RS26650 LysR family transcriptional regulator — —
Enterobacter sp. TBS_079 0.54 MPMX20_00177 Glyoxylate/hydroxypyruvate reductase B 0.46 MPMX20_04452 HTH-type transcriptional regulator MetR low > 85
Klebsiella michiganensis M5al 0.54 BWI76_RS26960 bifunctional glyoxylate/hydroxypyruvate reductase B 0.42 BWI76_RS01275 LysR family transcriptional regulator low > 92
Pantoea sp. MT58 0.54 IAI47_00110 glyoxylate/hydroxypyruvate reductase GhrB 0.43 IAI47_18315 HTH-type transcriptional regulator MetR low > 76
Rahnella sp. WP5 0.53 EX31_RS05925 glyoxylate/hydroxypyruvate reductase GhrB 0.43 EX31_RS25370 HTH-type transcriptional regulator MetR low > 89
Escherichia coli Nissle 1917 0.53 ECOLIN_RS20330 glyoxylate/hydroxypyruvate reductase GhrB 0.45 ECOLIN_RS30005 HTH-type transcriptional regulator MetR — —
Escherichia fergusonii Becca 0.52 EFB2_00254 Glyoxylate/hydroxypyruvate reductase B 0.45 EFB2_04809 HTH-type transcriptional regulator MetR low > 86
Escherichia coli ECRC101 0.52 OKFHMN_16020 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 OKFHMN_14330 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC102 0.52 NIAGMN_13780 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 NIAGMN_12085 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECOR27 0.52 NOLOHH_07965 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 NOLOHH_06460 metR HTH-type transcriptional regulator MetR low > 57
Escherichia coli ECRC99 0.52 KEDOAH_12130 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 KEDOAH_13820 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC62 0.52 BNILDI_03580 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 BNILDI_05070 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECRC101 0.52 MCAODC_06535 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 MCAODC_04835 metR HTH-type transcriptional regulator MetR — —
Escherichia coli BL21 0.52 ECD_03403 glyoxylate/hydroxypyruvate reductase B 0.45 ECD_03707 methionine biosynthesis regulon transcriptional regulator low > 60
Escherichia coli ECRC98 0.52 JDDGAC_19650 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 JDDGAC_17955 metR HTH-type transcriptional regulator MetR — —
Escherichia coli ECOR38 0.52 HEPCGN_14910 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.45 HEPCGN_13030 metR HTH-type transcriptional regulator MetR low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.52 GFF458 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 0.44 GFF253 Transcriptional activator MetR low > 78
Escherichia coli HS(pFamp)R (ATCC 700891) 0.52 OHPLBJKB_00153 Glyoxylate/hydroxypyruvate reductase B 0.45 OHPLBJKB_04223 HTH-type transcriptional regulator MetR low > 73
Escherichia coli BW25113 0.52 b3553 yiaE putative dehydrogenase (VIMSS) 0.45 b3828 metR DNA-binding transcriptional activator, homocysteine-binding (NCBI) low > 76
Serratia liquefaciens MT49 0.51 IAI46_00085 glyoxylate/hydroxypyruvate reductase GhrB 0.44 IAI46_01030 HTH-type transcriptional regulator MetR low > 86
Cupriavidus basilensis FW507-4G11 0.51 RR42_RS09465 bifunctional glyoxylate/hydroxypyruvate reductase B 0.46 RR42_RS30655 LysR family transcriptional regulator low > 128
Enterobacter asburiae PDN3 0.50 EX28DRAFT_3817 Lactate dehydrogenase and related dehydrogenases 0.45 EX28DRAFT_4493 Transcriptional regulator low > 76
Castellaniella sp019104865 MT123 0.48 ABCV34_RS08615 D-glycerate dehydrogenase 0.56 ABCV34_RS04450 LysR substrate-binding domain-containing protein low > 48
Dickeya dianthicola ME23 0.48 DZA65_RS00195 glyoxylate/hydroxypyruvate reductase GhrB 0.43 DZA65_RS00870 HTH-type transcriptional regulator MetR low > 75
Variovorax sp. OAS795 0.47 ABID97_RS20025 D-glycerate dehydrogenase 0.47 ABID97_RS19400 LysR family transcriptional regulator — —
Ralstonia solanacearum GMI1000 0.41 RS_RS21645 D-glycerate dehydrogenase 0.46 RS_RS20365 LysR family transcriptional regulator low > 80
Acidovorax sp. GW101-3H11 0.41 Ac3H11_2599 Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 0.51 Ac3H11_2344 Transcriptional activator MetR low > 79
Ralstonia solanacearum PSI07 0.40 RPSI07_RS02805 D-glycerate dehydrogenase 0.47 RPSI07_RS02550 LysR family transcriptional regulator low > 81
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS14340 D-glycerate dehydrogenase 0.47 RALBFv3_RS20315 LysR family transcriptional regulator low > 76
Ralstonia solanacearum UW163 0.35 UW163_RS11805 D-glycerate dehydrogenase 0.47 UW163_RS18860 LysR family transcriptional regulator — —
Pseudomonas stutzeri RCH2 0.29 Psest_0431 Lactate dehydrogenase and related dehydrogenases 0.90 Psest_1450 Transcriptional regulator — —

Not shown: 14 genomes with orthologs for PP_3376 only; 12 genomes with orthologs for PP_1063 only